Here you are: IMGT Web resources > IMGT Repertoire (IG and TR) > 1. Locus and genes

"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) rearranged (R), transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

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Positions in the sequence: limits from the first nucleotide of D-REGION to the last nucleotide.

IMGT subgroup IMGT gene name IMGT allele name Fct R T Pr Positions in the locus IMGT/LIGM-DB reference sequences IMGT/LIGM-DB sequences from the literature
Strain Clone names Accession numbers Positions in the sequence (D-REGION) Secondary accession numbers Strain Clone names Accession numbers Positions in the sequence (D-REGION)
IGHD1 IGHD1-1 IGHD1-1*01 ORF BAC9_6 DQ400445 [1] (1) 181257-181277
IGHD1-2 IGHD1-2*01 F BAC9_6 DQ400445 [1] 189019-189029
IGHD1-2*02 F + + DH3 AF161289 [2] 69-79
IGHD1-3 IGHD1-3*01 F BAC9_6 DQ400445 [1] 189882-189894
IGHD1-3*02 F + + DH2 AF161288 [2] 69-81
IGHD1-4 IGHD1-4*01 F BAC9_6 DQ400445 [1] 190813-190826
IGHD1-5 IGHD1-5*01 F BAC9_6 DQ400445 [1] 192925-192934
IGHD1-6 IGHD1-6*01 F BAC9_6 DQ400445 [1] 196844-196862
IGHD1-6*02 F + + DH1 AF161287 [2] 69-87
IGHD2 IGHD2-1 IGHD2-1*01 (F) + + DH AF068137 [3] ~VDJ 4029-4040

~VDJ: VDJ genomic DNA rearranged in the locus.

IMGT notes:
  1. (1) ORF because of non canonical RS
IMGT references:
  1. [1] Bengtén E. et al., Immunogenetics., 58, 831-844 (2006). PMID:16941126
  2. [2] Hayman J.R. et al., J. Immunol., 164, 1916-1924 (2000). PMID:10657641
  3. [3] Ghaffari S.H. et al., J. Immunol., 162, 1519-1529 (1999). PMID:9973409
Created:
01/04/2010
Last updated:
08/09/2011
Authors:
Nathalie Bosc & Amandine Lacan