IMGT Repertoire (IG and TR)

Fct: FUNCTIONALITY
- F: Functional
- P: Pseudogene
- ORF: Open Reading Frame
R: Rearranged
T: Transcribed
Pr: Translated into protein

"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) rearranged (R), transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

Click on:

IMGT gene name to get the corresponding IMGT/GENE-DB entry,
IMGT allele name to see the corresponding Alignments of alleles,
accession number to get the corresponding IMGT/LIGM-DB entry.

The Goldfish (Carassius auratus) IGHV genes have a temporary designation based on the IMGT gene name nomenclature rules for the unmapped genes, the incomplete loci, or the cDNAs in the absence of germline genes.

IMGT subgroup	IMGT gene name	IMGT allele name	Fct		R	T	Pr	Positions in the locus	IMGT/LIGM-DB reference sequences						IMGT/LIGM-DB sequences from the literature
IMGT subgroup	IMGT gene name	IMGT allele name	Fct		R	T	Pr	Positions in the locus	Strain	Clone names	Accession numbers	Positions in the sequence	Secondary accession numbers		Strain	Clone names	Accession numbers	Positions in the sequence
IGHV1	IGHV1S1	IGHV1S1*01	F								V3		J03616	[1,2]
IGHV2	IGHV2S1	IGHV2S1*01	ORF	(1)							99A		X61312	[3]
IGHV2	IGHV2S2	IGHV2S2*01	P	(2)							6X		X65266	[3]
IGHV3	IGHV3S1	IGHV3S1*01	P	(3)							99B		X61313	[3]

IMGT notes:

(1) Non canonical V-HEPTAMER: CACTGTT instead of CACAGTG.
(2) In frame STOP-CODONs in FR1-IMGT.
(3) In frame STOP-CODONs in FR1-IMGT and in CDR1-IMGT.
(4) J03617 originally assigned to Carassius auratus has been showed to be a human sequence (see [1] and [2]).

IMGT references:

[1] Wilson M.R. et al., Proc. Natl. Acad. Sci. U.S.A., 85, 1566-1570 (1988). PMID:3125551
[2] Erratum - Wilson M.R. et al., Proc. Natl. Acad. Sci. U.S.A., 86, 3276 (1989). PMID:3125551
[3] Wilson M.R. et al., Mol. Immunol., 28, 449-457 (1991). PMID:1905783

See also (IMGT Scientific chart):

Created:: 08/09/1999
Last updated:: 22/09/2023
Authors:: Sylvaine Artero

IMGT Repertoire (IG and TR)

Gene table: goldfish (Carassius auratus) IGHV