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"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

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M1 and M2 exons are not shown if not yet isolated.

IMGT gene name IMGT allele name Fct T Pr Positions in the locus IMGT/LIGM-DB reference sequences IMGT/LIGM-DB sequences from the literature
Strain Clone names Exons Accession numbers Positions in the sequence Secondary accession numbers Strain Clone names Accession numbers Positions in the sequence
IGHM1 IGHM1*01 F 3050 CH1 X07781 [1] 3050 M17186 [2] (1)
CH2 X07781 [1]
CH3 X07781 [1]
CH4(including CHS) X07781 [1]
M1 X07781 [1]
M2 X07781 [1]
IGHM2 IGHM2*01 F 6121 CH1 X07782 [1] c (s)
CH2 X07782 [1] c (s)
CH3 X07782 [1] c (s)
CH4(including CHS) X07782 [1] c (s)
IGHM3 IGHM3*01 F 6125 CH1 X07783 [1] c (s)
CH2 X07783 [1] c (s)
CH3 X07783 [1] c (s)
CH4(including CHS) X07783 [1] c (s)
IGHM4 IGHM4*01 F 12022 CH1 X07784 [1] c (s)
CH2 X07784 [1] c (s)
CH3 X07784 [1] c (s)
CH4(including CHS) X07784 [1] c (s)
IGHM5 IGHM5*01 F 3047 CH1 M17184 [2] (1)
CH2
CH3
CH4(including CHS)
IGHM6 IGHM6*01 F 801 CH1 M17187 [2] (1)
CH2
CH3
CH4(including CHS)
IGHM7 IGHM7*01 F 3083 CH1 M17185 [2] (1)
CH2
CH3
CH4(including CHS)
IGHM8 IGHM8*01 F 3089 CH1 M17188 [2] (1)
CH2
CH3
CH4(including CHS)
IGHM9 IGHM9*01 F CH1
CH2
5301TM CH3 X07785 [1] (1) c (m)
CH4(including M) X07785 [1] (1) c (m)

c: cDNA sequence.
(s): transcript of a secreted chain.
(m): transcript of a membrane chain.

IMGT notes:
  1. (1) Partial C-REGION.
IMGT references:
  1. [1] Kokubu F. et al., EMBO J., 7, 1979-1988 (1988). PMID:3138109
  2. [2] Kokubu F. et al., Proc. Natl. Acad. Sci. USA, 84, 5868-5872 (1987). PMID:3475706
Created:
31/01/2002
Last updated:
22/09/2023
Authors:
Dominique Scaviner