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"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) rearranged (R), transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

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The Horn shark (Heterodontus francisci) IGIJ genes and alleles have a temporary designation based on the IMGT gene name nomenclature rules for the unmapped genes, the incomplete loci, or the cDNAs in the absence of germline genes.

IMGT gene name IMGT allele name Fct R T Pr Positions in the locus IMGT/LIGM-DB reference sequences IMGT/LIGM-DB sequences from the literature
Strain Clone names Accession numbers Positions in the sequence Secondary accession numbers Strain Clone names Accession numbers Positions in the sequence
IGIJ1S1 IGIJ1S1*01 F λ141 X15315 [1]
IGIJ1S2 IGIJ1S2*01 F λ122 X15316 [1]
IGIJ1S3 IGIJ1S3*01 (F) + + 1501 M24368 [2] #c
IGIJ1S4 IGIJ1S4*01 (F) + + 1301 M64307 [2] #c
IGIJ2S1 IGIJ2S1*01 (F) + + HfrK4 L25561 [3] #c
IGIJ2S2 IGIJ2S2*01 (F) + + HfrK5 L25562 [3] #c
IGIJ2S3 IGIJ2S3*01 (F) + + HfrK6 L25563 [3] #c
IGIJ3S1 IGIJ3S1*01 (F) + + Hfr1A1 L25558 [3] ~VJ
IGIJ3S2 IGIJ3S2*01 (F) + + Hfr1B1 L25560 [3] ~VJ

#c: rearranged cDNA.
~VJ: VJ genomic DNA rearranged in the cassette.

IMGT references:
  1. [1] Shamblott M.J. et al., EMBO J., 8, 3733-3739 (1989). PMID:2511000
  2. [2] Shamblott M.J. et al., Proc. Natl. Acad. Sci. USA, 86, 4684-4688 (1989). PMID:2499889
  3. [3] Rast J.P. et al., Immunogenetics, 40, 83-99 (1994). PMID:8026868
Created:
07/10/2003
Last updated:
29/06/2011
Authors:
Dominique Scaviner