IMGT Repertoire (IG and TR)

Fct: FUNCTIONALITY
- F: Functional
- P: Pseudogene
- ORF: Open Reading Frame
R: Rearranged
T: Transcribed
Pr: Translated into protein

"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) rearranged (R), transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

Click on:

IMGT gene name to get the corresponding IMGT/GENE-DB entry,
IMGT allele name to see the corresponding Alignments of alleles,
accession number to get the corresponding IMGT/LIGM-DB entry.

The Horn shark (Heterodontus francisci) IGIV genes and alleles have a temporary designation based on the IMGT gene name nomenclature rules for the unmapped genes, the incomplete loci, or the cDNAs in the absence of germline genes.

IMGT subgroup	IMGT gene name	IMGT allele name	Fct	R	T	Pr	Positions in the locus	IMGT/LIGM-DB reference sequences							IMGT/LIGM-DB sequences from the literature
IMGT subgroup	IMGT gene name	IMGT allele name	Fct	R	T	Pr	Positions in the locus	Strain	Clone names	Accession numbers	Positions in the sequence	Secondary accession numbers			Strain	Clone names	Accession numbers	Positions in the sequence
IGIV1	IGIV1S1	IGIV1S1*01	F							λ141		X15315	[1]
	IGIV1S2	IGIV1S2*01	F							λ122		X15316	[1]
	IGIV1S3	IGIV1S3*01	(F)		+	+				1501		M24368	[2]	#c
	IGIV1S4	IGIV1S4*01	(F)		+	+				1301		M64307	[2]	#c
IGIV2	IGIV2S1	IGIV2S1*01	(F)		+	+				HfrK4		L25561	[3]	#c
	IGIV2S2	IGIV2S2*01	(F)		+	+				HfrK5		L25562	[3]	#c
	IGIV2S3	IGIV2S3*01	(F)		+	+				HfrK6		L25563	[3]	#c
IGIV3	IGIV3S1	IGIV3S1*01	(F)		+	+				Hfr1A1		L25558	[3]	~VJ
IGIV3	IGIV3S2	IGIV3S2*01	(F)		+	+				Hfr1B1		L25560	[3]	~VJ

#c: rearranged cDNA.
~VJ: VJ genomic DNA rearranged in the cassette.

IMGT references:

[1] Shamblott M.J. et al., EMBO J., 8, 3733-3739 (1989). PMID:2511000
[2] Shamblott M.J. et al., Proc. Natl. Acad. Sci. USA, 86, 4684-4688 (1989). PMID:2499889
[3] Rast J.P. et al., Immunogenetics, 40, 83-99 (1994). PMID:8026868

See also (IMGT Scientific chart):

Created:: 25/09/2003
Last updated:: 22/09/2023
Authors:: Dominique Scaviner

IMGT Repertoire (IG and TR)

Gene table: horn shark (Heterodontus francisci) IGIV