IMGT Repertoire (IG and TR)

Fct: FUNCTIONALITY
- F: Functional
- P: Pseudogene
- ORF: Open Reading Frame
T: Transcribed
Pr: Translated into protein

"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

Click on:

IMGT gene name to get the corresponding IMGT/GENE-DB entry,
IMGT allele name to see the corresponding Alignments of alleles,
accession number to get the corresponding IMGT/LIGM-DB entry.

TRGC1, TRGC2 and TRGC6 are localized in the TRG2 locus on ovine chromosome 4 at 4q2.2.
TRGC5, TRGC3 and TRGC4 are localized in the TRG1 locus on ovine chomosome 4 at 4q3.1.

To take into account the similitude between the organization of the ovine and bovine TRG loci, the ovine C6, C1 and C4 genes, described in [3] have been officially named as TRGC1, TRGC4 and TRGC6, respectively (20/04/2006).

IMGT gene name	IMGT allele name	Fct	T	Pr	Positions in the locus	IMGT/LIGM-DB reference sequences						IMGT/LIGM-DB sequences from the literature
IMGT gene name	IMGT allele name	Fct	T	Pr	Positions in the locus	Breed	Clone names	Exons	Accession numbers	Positions in the sequence	Secondary accession numbers	Breed			Clone names	Accession numbers	Positions in the sequence
	TRGC1	TRGC1*01	F						Altamurana	C6 (lambda17A5)	EX1	AF312559	[3]
											EX2A	AF312560	[3]
											EX3	AF312561	[3]
	TRGC2	TRGC2*01	F						White Alpine	C2a	EX1	Z12965	[1]	#c
											EX2A	Z12965	[1]	#c
											EX2B	Z12965	[1]	#c
											EX2C	Z12965	[1]	#c
											EX3	Z12965	[1]	#c
		TRGC2*02	F						Altamurana	C2b (lambda12A6)	EX1	AF312555	[3]
											EX2A	AF312556	[3]
											EX2B	AF312556	[3]
											EX2C	AF312557	[3]
											EX3	AF312558	[3]
	TRGC3	TRGC3*01	F						White Alpine		EX1	Z12966	[2]	#c
											EX2A	Z12966	[2]	#c
											EX2C	Z12966	[2]	#c
											EX3	Z12966	[2]	#c
		TRGC3*02	F						Altamurana	C3 (lambda3U3)	EX1	AF234763	[3]
											EX2A	AF234764	[3]
											EX2C	AF234764	[3]
											EX3	AF234764	[3]
	TRGC4	TRGC4*01	F						White Alpine	C1	EX1	Z12964	[1]	#c			Altamurana	gamma1 (lambda 16A3)	AF047015	[3]
											EX2A	Z12964	[1]	#c
											EX2B	Z12964	[1]	#c
											EX2C	Z12964	[1]	#c
											EX3	Z12964	[1]	#c
	TRGC5	TRGC5*01	F						White Alpine		EX1	Z13986	[2]	#c
											EX2A	Z13986	[2]	#c
											EX3	Z13986	[2]	#c
	TRGC6	TRGC6*01	F						Altamurana	C4 (lambda4P1, lambda4R1)	EX1	AF241307	[3]				White Alpine		Z12967	[2]	#c
											EX2A	AF241308	[3]				White Alpine		Z12967	[2]	#c
											EX2B	AF241308	[3]				White Alpine		Z12967	[2]	#c
											EX2C	AF241308	[3]				White Alpine		Z12967	[2]	#c
											EX3	AF241309	[3]				White Alpine		Z12967	[2]	#c

#c: rearranged cDNA

IMGT references:

[1] Hein W.R. et al., Eur. J. Immunol., 20, 1795-1804 (1990). PMID:2145166
[2] Hein W.R. and Dudler L., EMBO J., 12, 712-724 (1993). PMID:8440261
[3] Miccoli M. C. et al., J. Mol. Evol., 57, 52-62 (2003). PMID:12962306
[4] Vaccarelli G. et al., BMC Genomics, 9, 81 (2008). PMID:18282289

See also (IMGT Scientific chart):

Created:: 11/06/2001
Last updated:: 22/09/2023
Authors:: Christèle Martinez-Jean, Yan Wu and Marie-Paule Lefranc

IMGT Repertoire (IG and TR)

Gene table: sheep (Ovis aries) TRGC