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"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

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M1 and M2 exons are not shown if not yet isolated.

IMGT gene name IMGT allele name Fct T Pr Positions in the locus IMGT/LIGM-DB reference sequences IMGT/LIGM-DB sequences from the literature
Strain Clone names Exons Accession numbers Positions in the sequence Secondary accession numbers Strain Clone names Accession numbers Positions in the sequence
IGHM1 IGHM1*01 CH1
CH2
CH3
CH4
IGHW1 IGHW1*01 F 4RACE CH1 U40560 [1] c(s)
CH2 U40560 [1] c(s)
CH3 U40560 [1] c(s)
CH4 U40560 [1] c(s)
CH5 U40560 [1] c(s)
CH6 (including CHS) U40560 [1] c(s)
IGHW2 IGHW2*01 F 2spleen CH1 U50605 [1] (1) c
CH2
CH3
CH4
CH5
CH6 (including CHS)

c: cDNA sequence.
(s): transcript of secreted chain.

IMGT notes:
  1. (1) C-REGION is partial: CH1 is partial in 3'.
IMGT references:
  1. [1] Bernstein R.M. et al., Proc. Natl. Acad. Sci. U.S.A., 93, 3289-3293 (1996). PMID:8622930
Created:
31/01/2002
Last updated:
22/09/2023
Authors:
Dominique Scaviner