IMGT Repertoire (IG and TR)

Fct: FUNCTIONALITY
- F: Functional
- P: Pseudogene
- ORF: Open Reading Frame
R: Rearranged
T: Transcribed
Pr: Translated into protein

"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) rearranged (R), transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

Click on:

IMGT gene name to get the corresponding IMGT/GENE-DB entry,
IMGT allele name to see the corresponding Alignments of alleles,
accession number to get the corresponding IMGT/LIGM-DB entry.

The Sandbar shark (Carcharhinus plumbeus) IGHV genes and allele have a temporary designation based on the IMGT gene name nomenclature rules for the unmapped genes, the incomplete loci, or the cDNAs in the absence of germline genes.
Sandbar shark (Carcharhinus plumbeus) genes are designated by a number for the subgroup followed by the letter S and a number.

IMGT subgroup	IMGT gene name	IMGT allele name	Fct	R	T	Pr	Positions in the locus	IMGT/LIGM-DB reference sequences							IMGT/LIGM-DB sequences from the literature
IMGT subgroup	IMGT gene name	IMGT allele name	Fct	R	T	Pr	Positions in the locus	Strain	Clone names	Accession numbers	Positions in the sequence	Secondary accession numbers			Strain	Clone names	Accession numbers	Positions in the sequence
IGHV1	IGHV1S1	IGHV1S1*01	(F)		+	+				4 RACE		U40560	[1]	#c
	IGHV1S2	IGHV1S2*01	(F)		+	+				6 spleen		U50604	[1]	#c
	IGHV1S3	IGHV1S3*01	(F)		+	+				8 RACE		U50605	[1]	#c
	IGHV1S4	IGHV1S4*01	(F)		+	+				1 RACE		U50606	[1]	#c
	IGHV1S5	IGHV1S5*01	(F)		+	+				2 spleen		U50607	[1]	#c
	IGHV1S6	IGHV1S6*01	(F)		+	+				7 spleen		U50608	[1]	#c
	IGHV1S7	IGHV1S7*01	(F)		+	+				1 spleen		U50609	[1]	#c
	IGHV1S8	IGHV1S8*01	(F)		+	+				7 RACE		U50610	[1]	#c

#c: rearranged cDNA.

IMGT references:

[1] Bernstein R.M. et al., Proc. Natl. Acad. Sci. U.S.A., 93, 3289-3293 (1996). PMID:8622930
[2] Roman T. et al., Immunogenetics, 43, 325-326 (1996). PMID:9110939

See also (IMGT Scientific chart):

Created:: 06/07/2000
Last updated:: 22/09/2023
Authors:: Lorena Betancourt, Dominique Scaviner

IMGT Repertoire (IG and TR)

Gene table: sandbar shark (Carcharhinus plumbeus) IGHV