IMGT Repertoire (IG and TR)

Fct: FUNCTIONALITY
- F: Functional
- P: Pseudogene
- ORF: Open Reading Frame
R: Rearranged
T: Transcribed
Pr: Translated into protein

"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) rearranged (R), transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

Click on:

IMGT gene name to get the corresponding IMGT/GENE-DB entry,
IMGT allele name to see the corresponding Alignments of alleles,
accession number to get the corresponding IMGT/LIGM-DB entry.

The sequenced Spotted wobbegong (Orectolobus maculatus) IGHV genes are rearranged to IGHJ associated to IGHN in different cassettes. The cassettes are of the type 2, described for the Nurse shark (Ginglymostoma cirratum) cassettes, as they are characterized by a V-GENE having an amino acid other than Cys in 40 and a J-GENE having an amino acid other than Cys in 118.

cDNAs have been included in this table as they are informative for the gene content of the corresponding genomic cassettes.
M1 and M2 exons are not shown if not yet isolated.

Cassette		Cassette type	Clone name	Gene name	Exon	Accession numbers
Cassette		Cassette type	Clone name	Gene name	Exon	Accession numbers
1	#c		7E-23	IGHV2S1		AF336087
				IGHD1		AF336087
				IGHJ1		AF336087
				IGHN1	CH1	AF336087
					CH2
					CH3
					CH4
					CH5
2	#c		7E-51	IGHV2S2		AF336088
				IGHD2		AF336088
				IGHJ2		AF336088
				IGHN2	CH1	AF336088
					CH2
					CH3
					CH4
					CH5
3	#c		7E-54	IGHV2S3		AF336089
				IGHD3		AF336089
				IGHJ3		AF336089
				IGHN3	CH1	AF336089
					CH2
					CH3
					CH4
					CH5
4	#c		7E-60	IGHV2S4		AF336090
				IGHD4		AF336090
				IGHJ4		AF336090
				IGHN4	CH1	AF336090
					CH2
					CH3
					CH4
					CH5
5	#c		7E-68	IGHV2S5		AF336091
				IGHD5		AF336091
				IGHJ5		AF336091
				IGHN5	CH1	AF336091
					CH2
					CH3
					CH4
					CH5
6	#c		7E-80	IGHV2S6		AF336092
				IGHD6		AF336092
				IGHJ6		AF336092
				IGHN6	CH1	AF336092
					CH2
					CH3
					CH4
					CH5
7	#c		7E-93	IGHV2S7		AF336093
				IGHD7		AF336093
				IGHJ7		AF336093
				IGHN7	CH1	AF336093
					CH2
					CH3
					CH4
					CH5
8	#c		7R-1	IGHV2S8		AF336094
				IGHD8		AF336094
				IGHJ8		AF336094
				IGHN8	CH1
					CH2
					CH3
					CH4
					CH5

#c: rearranged cDNA.

See also (IMGT Scientific chart):

Created:: 28/01/2002
Last updated:: 22/09/2023
Authors:: Dominique Scaviner

IMGT Repertoire (IG and TR)

Gene table - Cassette gene content: spotted wobbegong (Orectolobus maculatus) IGH