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"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) rearranged (R), transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

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The Torafugu (Takifugu rubripes) IGHV genes and alleles have a temporary designation based on the IMGT gene name nomenclature rules for the unmapped genes, the incomplete loci, or the cDNAs in the absence of germline genes.

IMGT subgroup IMGT gene name IMGT allele name Fct R T Pr Positions in the locus IMGT/LIGM-DB reference sequences IMGT/LIGM-DB sequences from the literature
Strain Clone names Accession numbers Positions in the sequence Secondary accession numbers Strain Clone names Accession numbers Positions in the sequence
IGHV1 IGHV1S1 IGHV1S1*01 F F-Vh1 AF108421 [1]
IGHV1S2 IGHV1S2*01 F F-Vh3 AF108421 [1]
IGHV1S3 IGHV1S3*01 F F-Vh5 AF108421 [1]
IGHV1S4 IGHV1S4*01 F F-Vh6 AF108422 [1]
IGHV1S5 IGHV1S5*01 F F-Vh7 AF108423 [1]
IGHV2 IGHV2S1 IGHV2S1*01 ORF (1) F-Vh2 AF108421 [1]
IGHV2S2 IGHV2S2*01 ORF (1) F-Vh4 AF108421 [1]
IGHV2S3 IGHV2S3*01 ORF (1) F-Vh8 AF108423 [1]
IGHV2S4 IGHV2S4*01 ORF (1) F-Vh9 AF108422 [1] (2)
IMGT notes:
  1. (1) Non canonical V-HEPTAMER: CACAATA instead of CACAGTG.
  2. (2) Partial V-REGION: AA 1 to 89 are absent (no FR1-IMGT, no CDR1-IMGT, no FR2-IMGT, no CDR2-IMGT, partial FR3-IMGT).
IMGT references:
  1. [1] Peixoto B.R. and Brenner S., Immunogenetics, 51, 443-451 (2000). PMID:10866111
Last updated:
Sylvaine Artero