IMGT Repertoire (IG and TR)

Fct: FUNCTIONALITY
- F: Functional
- P: Pseudogene
- ORF: Open Reading Frame
T: Transcribed
Pr: Translated into protein

"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

Click on:

IMGT gene name to get the corresponding IMGT/GENE-DB entry,
IMGT allele name to see the corresponding Alignments of alleles,
accession number to get the corresponding IMGT/LIGM-DB entry.

IMGT gene name	IMGT allele name	Fct	Chromosomal localization	T	Pr	IMGT/LIGM-DB locus reference sequences						IMGT/LIGM-DB sequences from the literature
IMGT gene name	IMGT allele name	Fct	Chromosomal localization	T	Pr	Breed	Clone names	Exons	Accession numbers	Positions in the sequence	Secondary accession numbers	Breed				Clone names	Accession numbers	Positions in the sequence
	TRBC1	TRBC1*01	F			16	+		Boxer	CM000016.3	EX1	IMGT000005	[3]		MAP	248958-249344		Boxer	AAEX02035465	[1]		complement(45089-45475)
											EX2	IMGT000005	[3]		MAP	250045-250062		Boxer	AAEX02035465	[1]		complement(44371-44388)
											EX3	IMGT000005	[3]	(1)	MAP	250220-250326		Boxer	AAEX02035465	[1]	(1)	complement(44107-44213)
											EX4	IMGT000005	[3]	(1)	MAP	250621-250638		Boxer	AAEX02035465	[1]	(1)	complement(43795-43812)
		TRBC1*02	F								EX1	HE653929	[2]	(2)		2468-2854
											EX2	HE653929	[2]	(2)		3552-3569
											EX3	HE653929	[2]	(1,2)		3727-3833
											EX4	HE653929	[2]	(1,2)		4157-4174
	TRBC2	TRBC2*01	F				+	-			EX1	HE653929	[2]	(2)		11730-12116
											EX2	HE653929	[2]	(2)		12817-12834
											EX3	HE653929	[2]	(1,2)		12992-13098
											EX4	HE653929	[2]	(1,2)		13394-13411

MAP: Mapped reference sequences.

IMGT notes:

(1) Functional but have a splicing frame 0 (sf0) between EX3 and EX4
(2) Sequence not in locus reference sequence (assembly CanFam3.1)

IMGT references:

[1] Lindblad-Toh K. et al., Nature, 438, 803-819 (2005). PMID:16341006
[2] Mineccia M. et al., Dev Comp Immunol., 37, 279-293 (2012). PMID:22465586
[3] Martin J. et al. Immunogenetics 2018 Apr;70(4):223-236 (2018). doi: 10.1007/s00251-017-1028-0. Epub 2017 Sep 19.. PMID:28924718

More information:

See also (IMGT Scientific chart):

Created:: 30/11/2009
Last updated:: 22/09/2023
Authors:: Giovanna Linguiti, Emilie Carillon, Amandine Lacan, Perrine Pégorier

IMGT Repertoire (IG and TR)

Gene table: dog (Canis lupus familiaris) TRBC