IMGT Repertoire (IG and TR)

Fct: FUNCTIONALITY
- F: Functional
- P: Pseudogene
- ORF: Open Reading Frame
R: Rearranged
T: Transcribed
Pr: Translated into protein

"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) rearranged (R), transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

Click on:

IMGT gene name to get the corresponding IMGT/GENE-DB entry,
IMGT allele name to see the corresponding Alignments of alleles,
accession number to get the corresponding IMGT/LIGM-DB entry.

Haplotypes have been described in Mattila, P.S et al., Eur. J. Immunol., 25, 2578-2582 (1995).

IMGT gene name	IMGT allele name	Fct	Chromosomal localization		R	T	Pr	Positions in the locus	IMGT/LIGM-DB reference sequences				IMGT/LIGM-DB sequences from the literature
IMGT gene name	IMGT allele name	Fct	Chromosomal localization		R	T	Pr	Positions in the locus	Clone names	Accession numbers	Positions in the sequence (J-GENE-UNIT)	Secondary accession numbers	Clone names			Accession numbers	Positions in the sequence (J-GENE-UNIT)
	IGHJ1	IGHJ1*01	F	(8)	14q32.33						J1		J00256	[1]	(1)	686-774				X86355	[3]	(2)	247-336
																				X86356	[3]	(2)
																				X86357	[3]	(2)
																				X86358	[3]	(2)
																				X86359	[3]	(2)
																				X97051	[4]
	IGHJ1P	IGHJ1P*01	P		14q32.33						J1P		J00256	[1]	(1)	467-557				X86355	[3]	(2)	30-120
																				X86356	[3]	(2)
																				X86357	[3]	(2)
																				X86358	[3]	(2)
																				X86359	[3]	(2)
																				X97051	[4]
		IGHJ1P*02	P		14q32.33						CM000676.2		IMGT000035		(1)(6)	1014131-1014221
	IGHJ2	IGHJ2*01	F		14q32.33						J2		J00256	[1]	(1)	893-984				X86355	[3]	(2)	454-544
																				X86356	[3]	(2)
																				X86357	[3]	(2)
																				X86358	[3]	(2)
																				X86359	[3]	(2)
																				X97051	[4]
	IGHJ2P	IGHJ2P*01	P		14q32.33						J2P		J00256	[1]	(1)	1284-1380				X86355	[3]	(2)	853-952
																				X86356	[3]	(2)
																				X86357	[3]	(2)
																				X86358	[3]	(2)
																				X86359	[3]	(2)
																				X97051	[4]
		IGHJ2P*02	P		14q32.33						CM000676.2		IMGT000035		(1)(6)	1014955-1015054
	IGHJ3	IGHJ3*01	F		14q32.33						J3		J00256	[1]	(1)	1537-1586				M25625	[2]		31-119
		IGHJ3*02	F		14q32.33						J3		X86355	[3]	(2)	1068-1156				X97051	[4]
																				X86356	[3]	(2)
																				X86357	[3]	(2)
																				X86358	[3]	(2)
																				X86359	[3]	(2)
	IGHJ4	IGHJ4*01	F		14q32.33						J4		J00256	[1]	(1)	1873-1959
		IGHJ4*02	F		14q32.33						J4		X86355	[3]	(2)	1441-1527				X97051	[4]
																				X86356	[3]	(2)
																				X86357	[3]	(2)
																				X86358	[3]	(2)
																				X86359	[3]	(2)
		IGHJ4*03	F		14q32.33						J4		M25625	[2]	(5)	407-493
	IGHJ5	IGHJ5*01	F		14q32.33						J5		J00256	[1]	(1)	2317-2404	M25625	[2]
		IGHJ5*02	F		14q32.33						J5		X86355	[3]	(2)	1840-1928				X97051	[3]
																				X86356	[3]	(2)
																				X86357	[3]	(2)
																				X86358	[3]	(2)
																				X86359	[3]	(2)
	IGHJ3P	IGHJ3P*01	P		14q32.33						J3P		J00256	[1]	(1)	2709-2797	M25625	[2]
		IGHJ3P*02	P		14q32.33						J3P		X86355	[3]	(2)	2239-2326				X97051	[3]	(2)
																				X86356	[3]	(2)
																				X86357	[3]	(2)
																				X86358	[3]	(2)
																				X86359	[3]	(2)
	IGHJ6	IGHJ6*01	F		14q32.33						J6		J00256	[1]	(1)	2909-3009
		IGHJ6*02	F		14q32.33						J6		M25625	[2]	(5)	1442-1542				X86355	[3]	(3)
																				M63031	[5]	(7)
																				X86357	[3]	(3)
																				X86358	[3]	(3)
																				X97051	[4]
																				BK063800			1026639-1026739
																				BK063801			972316-972416
																				IMGT000147			1048895-1048995
		IGHJ6*03	F		14q32.33						J6		M63030	[5]	(7)	20-120				X86359	[3]	(4)
																				X86356	[3]	(4)
																			CM000676.2	IMGT000035			1016547-1016647	(7)
		IGHJ6*04	F		14q32.33						J6		AJ879487	[6]		1-101

IMGT notes:

(1) Sequenced in haplotype a.
(2) Sequenced in haplotypes b1, b1c, b2, b3 and c, respectively.
(3) Sequenced in haplotypes b1, b2 and b3, respectively.
(4) Sequenced in haplotypes b1c and c, respectively.
(5) Sequenced in haplotype d.
(6) No DONOR-SPLICE: ncc instead of ngt.
(7) Has a complete J-REGION.
(8) This allele is known to be associated to different functionalities (IMGT000110).

IMGT references:

[1] Ravetch J.V. et al., Cell, 27, 583-591 (1981). PMID:6101209
[2] Rabbitts T.H., Biochem. Soc. Trans., 11, 119-126 (1983). PMID:6420211
[3] Mattila P.S. et al., Eur. J. Immunol., 25, 2578-2582 (1995). PMID:7589129
[4] Corbett S. et al., J. Mol. Biol. 270, 587-597 (1997). PMID:9245589
[5] Nottenburg C. and Hasenstab, D., Unpublished.
[6] Ohm-Laursen L. et al., Immunogenetics, 57, 621-627 (2005). PMID:16133446

See also (IMGT Scientific chart):

Created:: 18/04/1997
Last updated:: 21/03/2024
Authors:: Nathalie Pallarès, Joumana Jabado Michaloud

IMGT Repertoire (IG and TR)

Gene table: human (Homo sapiens) IGHJ