IMGT Repertoire (IG and TR)

Correspondence between nomenclatures: human (Homo sapiens) IGHD

Citing this page: Ruiz, M. et al., Exp. Clin. Immunogenet., 16, 173-184 (1999) PMID: 10394055 pdf

Correspondence between IMGT gene names and clone names is available in Gene tables: human (Homo sapiens)

All the IMGT human IG and TR gene name have been approved by the HUGO Nomenclature Commitee in 1999 and entered in the Genome Database and into Entrez Gene at NCBI, USA.

Human IGHD segments are listed from 5' (top of the table) to 3' (bottom of the table).

IMGT gene name [7,8] Other designations from the literature
Siebenlist et al. [1] Ravetch et al. [2] Buluwela et al. [3] Matsuda et al. [5] Ichihara et al. [4]
IGHD1-1 M4
IGHD2-2 D4 LR4
IGHD3-3 23/7 XP4
IGHD4-4 A4
IGHD5-5 K4
IGHD6-6 N4
IGHD1-7 M1
IGHD2-8 D1 LR1
IGHD3-9 21/0,5 XP1
IGHD3-10 21/7 XP'1
IGHD4-11 A1
IGHD5-12 K1
IGHD6-13 N1
IGHD1-14 M2
IGHD2-15 D2 LR2
IGHD3-16 21/10 XP2
IGHD4-17 A2
IGHD5-18 K2
IGHD6-19 N2
IGHD1-20 M3
IGHD2-21 D3 LR3
IGHD3-22 21/9 XP3
IGHD4-23 A3
IGHD5-24 K3
IGHD6-25 N3
IGHD1-26 M'3
IGHD7-27 DHQ52

IGHD segments are designated by a number for the subgroup followed by an hyphen and a number for the localization from 5' to 3' in the locus [6].

IMGT references:
  1. [1] Siebenlist, U. et al., Nature, 294, 631-635 (1981). PMID:7312051
  2. [2] Ravetch, J.V. et al., Cell, 27, 583-591 (1981). PMID:6101209
  3. [3] Buluwela, L. et al., EMBO J., 7, 2003-2010 (1988). PMID:3138112
  4. [4] Ichihara, Y. et al., EMBO J., 7, 4141-4150 (1988). PMID:3243276
  5. [5] Matsuda F. et al., J. Exp. Med., 188, 2151-2162 (1998). PMID:9841928
  6. [6] Corbett, S. et al., J. Mol. Biol., 270, 587-597 (1997). PMID:9245589
  7. [7] Lefranc, M.-P., Exp. Clin. Immunogenet., 18, 100-116 (2001). PMID:11340299
  8. [8] Lefranc, M.-P. and Lefranc, G., The Immunoglobulin FactsBook, Academic Press, Harcourt, 458 pages (2001). 012441351X
Last updated:
Manuel Ruiz, Elodie Foulquier