This table lists reagents monoclonal antibodies, specific for the T cell Receptor Beta Variable (TRBV) regions, which are commercially available. The reactivities of the reagents monoclonal antibodies for different variable regions are shown between parentheses in the 'Clone name and Specificity' column. The reactivities as described in this table are not exhaustive. For more information on the products and their reactivity, please contact the companies: BD BioSciences Pharmingen, CEDARLANE laboratories Ltd.
Only functional TRBV genes are listed.
IMGT subgroup | IMGT gene name | Reagents monoclonal antibodies | ||||
---|---|---|---|---|---|---|
Clone name and Specificity | Company product | Species and Isotype | Strain host | Immunogen | ||
TRBV1 | TRBV1 | B20.6(TRBV1) | BD Pharmingen Vβ2 | Rat IgG2a,κ | LOU/W1 | Mouse cytotoxic T cell clone CW3/1.1 |
TRBV2 | TRBV2 | KT4(TRBV2) | BD Pharmingen Vβ4 | Rat IgG2b,κ | Sprague-Dawley | B10.D2 mouse T cell clone I3 |
TRBV2 | CTVB4(TRBV2) | CEDARLANE Vβ4 | Rat IgG2a | |||
TRBV3 | TRBV3 | |||||
TRBV4 | TRBV4 | B21.5(TRBV4) | BD Pharmingen Vβ10 | Rat IgG2a,λ | LOU/W1 | Soluble TR αβ from mouse cytotoxic T cell clone |
TRBV4 | CTVB10b(TRBV4) | CEDARLANE Vβ10 | Rat IgG2b | |||
TRBV5 | TRBV5 | |||||
TRBV6 | TRBV6 | |||||
TRBV7 | TRBV7 | |||||
TRBV8 | TRBV8 | |||||
TRBV9 | TRBV9 | |||||
TRBV10 | TRBV10 | |||||
TRBV11 | TRBV11 | |||||
TRBV12 | TRBV12-1 | MR9-4(TRBV12-1, TRBV12-2) | BD Pharmingen Vβ5.1/5.2 | Mouse IgG1,κ | SWR | Mouse T cell hybridoma 2HB51.8 |
TRBV12-2 | MR9-4(TRBV12-1, TRBV12-2) | BD Pharmingen Vβ5.1/5.2 | Mouse IgG1,κ | SWR | Mouse T cell hybridoma 2HB51.8 | |
TRBV12-3 | ||||||
TRBV13 | TRBV13-1 | F23.1(TRBV13-1,TRBV13-2,TRBV13-3) | BD Pharmingen Vβ8.1/8.2/8.3 | Mouse IgG2a,κ | C57L/J | BALB.B mouse lymph node and spleen T cells |
TRBV13-1 | 1B3.3(TRBV13-1) | BD Pharmingen Vβ8.3 | Armenian hamster IgG3,λ1 | Mouse Th1 clone 3.L2 | ||
TRBV13-1 | CT-8C1, CT8C1, KT-8C1(TRBV13-1) | CEDARLANE Vβ8.3 | Mouse IgG2a | |||
TRBV13-1 | CT-8E, CT8E, KT-8E(TRBV13-1,TRBV13-2) | CEDARLANE Vβ8.2/8.3 | Mouse IgG2a | |||
TRBV13-2 | F23.1(TRBV13-1,TRBV13-2,TRBV13-3) | BD Pharmingen Vβ8.1/8.2/8.3 | Mouse IgG2a,κ | C57L/J | BALB.B mouse lymph node and spleen T cells | |
TRBV13-2 | MR5-2(TRBV13-2, TRBV13-3) | BD Pharmingen Vβ8.1/8.2 | Mouse IgG2a,κ | C57L | C57BL/6 mouse helper T cell clone OI6 | |
TRBV13-2 | KJ16(TRBV13-2, TRBV13-3) | CEDARLANE Vβ8.1/8.2 | Rat IgG1 | |||
TRBV13-2 | CT-8E(TRBV13-1,TRBV13-2) | CEDARLANE Vβ8.2/8.3 | Mouse IgG2a | |||
TRBV13-3 | F23.1(TRBV13-1,TRBV13-2,TRBV13-3) | Pharmingen Vβ8.1/8.2/8.3 | Mouse IgG2a,κ | C57L/J | BALB.B mouse lymph node and spleen T cells | |
TRBV13-3 | MR5-2(TRBV13-2, TRBV13-3) | BD Pharmingen Vβ8.1/8.2 | Mouse IgG2a,κ | C57L | C57BL/6 mouse helper T cell clone OI6 | |
TRBV13-3 | KJ16(TRBV13-2, TRBV13-3) | CEDARLANE Vβ8.1/8.2 | Rat IgG1 | |||
TRBV14 | TRBV14 | MR12-3(TRBV14) | BD Pharmingen Vβ13 | Mouse IgG1,κ | C57BR | |
TRBV15 | TRBV15 | MR11-1(TRBV15) | BD Pharmingen Vβ12 | Mouse IgG1,κ | ||
TRBV15 | CTVB12b(TRBV15) | CEDARLANE Vβ12b | Rat IgG2a | |||
TRBV16 | TRBV16 | RR3-15(TRBV16) | BD Pharmingen Vβ11 | Rat IgG2b,κ | Mouse cytolytic T cell clone OH6 | |
TRBV16 | CTVB11(TRBV16) | CEDARLANE Vβ11 | Rat IgG2b | |||
TRBV17 | TRBV17 | MR10-2(TRBV17) | BD Pharmingen Vβ9 | Mouse IgG1,κ | Mouse T cell hybridoma 2BR18 | |
TRBV18 | TRBV18 | |||||
TRBV19 | TRBV19 | RR4-7(TRBV19) | BD Pharmingen Vβ6 | Rat IgG2b,λ | C57BL/6 mouse helper T cell clone OI1 | |
TRBV20 | TRBV20 | |||||
TRBV21 | TRBV21 | |||||
TRBV22 | TRBV22 | |||||
TRBV23 | TRBV23 | |||||
TRBV24 | TRBV24 | KJ23(TRBV24) | BD Pharmingen Vβ17 | Mouse IgG2a,κ | BALB/c | SWR Mouse T cells |
TRBV25 | TRBV25 | |||||
TRBV26 | TRBV26 | KJ25(TRBV26) | BD Pharmingen Vβ3 | Armenian hamster IgG2,κ | TR αβ purified from mouse T cell hybridoma 2B4.6 | |
TRBV27 | TRBV27 | |||||
TRBV28 | TRBV28 | |||||
TRBV29 | TRBV29 | TR310(TRBV29) | BD Pharmingen Vβ7 | Rat IgG2b,κ | Fischer | AKR/Cum mouse spontaneous T lymphoma cell line TK1 |
TRBV29 | TR310(TRBV29) | CEDARLANE Vβ7 | Rat IgG2b,κ | |||
TRBV30 | TRBV30 | |||||
TRBV31 | TRBV31 | 14-2(TRBV31) | BD Pharmingen Vβ14 | Rat IgM,κ | B10.A mouse helper T cell clone J9.19 |