Citing IMGT unique numbering for G-DOMAIN and G-LIKE-DOMAIN:
Lefranc, M.-P. et al., Dev. Comp. Immunol., 29, 917-938 (2005)
PMID: 15936075 with permission from Elsevier
G-ALPHA1 [D1] (MH1)
A AB B BC C CD D helix
(1-14) (18-28) (31-38) (42-49) (50-92B)
——————————————> ——————————> ———————> ———————> ———————————————————————————————————————————————————
1 7 10 14 18 21 28 31 38 42 45 49 50 54 61 68 72 74 80 92
0987654321 | .....|A..|...| ... |..|......| .. |......| ... |..|...|1234567 |...|ABC......|AB......|...|A.|.....|...........|AB
Homsap MH1-A (HLA-A*0201) (G)SHSMRY.FFTSVSR PGR GEPRFIAVGYV DD TQFVRFDS DAA SQRMEPRA....... PWIEQ...EGPEYWD..GETRKVKAHSQ.THRVDLGTLRGYYNQSEA....
Homsap MH1-A (HLA-A*0201) (G)SHSMRY.FFTSVSR PGR GEPRFIAVGYV DD TQFVRFDS DAA SQRMEPRA....... PWIEQ...EGPEYWD..GETRKVKAHSQ.THRVDLGTLRGYYNQSEA....
Homsap MH1-B (HLA-B*0702) (G)SHSMRY.FYTSVSR PGR GEPRFISVGYV DD TQFVRFDS DAA SPREEPRA....... PWIEQ...EGPEYWD..RNTQIYKAQAQ.TDRESLRNLRGYYNQSEA....
Homsap MH1-C (HLA-C*0701) (C)SHSMRY.FDTAVSR PGR GEPRFISVGYV DD TQFVRFDS DAA SPRGEPRA....... PWVEQ...EGPEYWD..RETQNYKRQAQ.ADRVSLRNLRGYYNQSED....
Homsap MH1-E (HLA-E*01) (G)SHSLKY.FHTSVSR PGR GEPRFISVGYV DD TQFVRFDN DAA SPRMVPRA....... PWMEQ...EGSEYWD..RETRSARDTAQ.IFRVNLRTLRGYYNQSEA....
Homsap MH1-F (HLA-F*01) (G)SHSLRY.FSTAVSR PGR GEPRYIAVEYV DD TQFLRFDS DAA IPRMEPRE....... PWVEQ...EGPQYWE..WTTGYAKANAQ.TDRVALRNLLRRYNQSEA....
Homsap MH1-G (HLA-G*01) (G)SHSMRY.FSAAVSR PGR GEPRFIAMGYV DD TQFVRFDS DSA CPRMEPRA....... PWVEQ...EGPEYWE..EETRNTKAHAQ.TDRMNLQTLRGYYNQSEA....
Musmus MH1-D1 (H2-D1*02) (G)PHSMRY.FETAVSR PGL EEPRYISVGYV DN KEFVRFDS DAE NPRYEPRA....... PWMEQ...EGPEYWE..RETQKAKGQEQ.WFRVSLRNLLGYYNQSAG....
Musmus MH1-K1 (MH1-K1*01) (G)PHSLRY.FVTAVSR PGL GEPRYMEVGYV DD TEFVRFDS DAE NPRYEPRA....... RWMEQ...EGPEYWE..RETQKAKGNEQ.SFRVDLRTLLGYYNQSKG....
Musmus MH1-L (H2-L*02) (G)PHSMRY.FETAVSR PGL GEPRYISVGYV DN KEFVRFDS DAE NPRYEPQA....... PWMEQ...EGPEYWE..RITQIAKGQEQ.WFRVNLRTLLGYYNQSAG....
Musmus MH1-M5 (H2-M5*02) (G)IHSLQF.FATTMTQ PGL REHSFIFVVFV DA TQFLCYNN KGK NQRMEPRP....... LWVKQ...MGPEYWE..QQTRTVKVIEK.IALVNLQEAMDIYNHSKD....
Musmus MH1-Q7 (H2-Q7*02) (G)QHSLQY.FHTAVSR PGL GEPWFISVGYV DD TQFVRFDS DAE NPRMEPRA....... RWMEQ...EGPEYWE..RETQIAKGHEQ.SFRGSLRTAQSYYNQSKG....
Musmus MH1-T3 (H2-T3*01) (G)SHSLRY.FYTALSR PAI SEPWYIAVGYL DD TQFVRFNS SGE TATYKLSA....... PWVEQ...EGPEYWA..RETEIVTSNAQ.FFRENLQTMLDYYNLSQN....
Ratnor MH1-A (RT1-A*01) (G)SHSLRY.FYTAVSR PGL GEPRFIAVGYV DD TEFVRFDS DAE NPRMEPRA....... RWMER...EGPEYWE..QQTRIAKEWEQ.IYRVDLRTLRGYYNQSEG....
Ambmex MH1-A (AMME-IA) (G)SHSFRG.FYSSLSE EVP GVPRFSAVGFV DD VPIEGYSS D.. TRRWEPRA....... PWMRKI..EDPQYWE..RETERARGTEP.VERANVGIVMERLNQTR.....
Saltru MH1-A (A)TNTLLY.YYTGTSG IP. NFPEFITVGIV NG HQIDHYDS I.. TKRAIQKA....... EWISGA..VDPDYWK..RNTQIYAANEP.FFKAGIDILKSRFNQTE.....
Onckis MH1-A (A)PHSLHR.HCIATQG T.. LYPKNIQLVMI DD VIVYYYNS S.. AEQEAIVP....... EWLNHP..EGIEFWQ..EVHRNLKFNRY.VMDTAVRVTSEHYNHS......
Oncmyk MH1-A*01 AB162342 (A)THSLRY.VYTATSG VP. DFPEFVSLGIV DG MQIDYYDS N.. TKRVVPKQ....... DWMAKT..EGSDYWE..RQTQNSIGDEQ.TFKANIDVAKQRFNQTG.....
Oncmyk MH1-B*01 AF091779 (A)PHSLHR.HCIATQG T.. LYPKNIQLVMI DD VIVYYYNS S.. AEQEAVVP....... EWLNHP..EGIEFWQ..EVHRNLKFNRY.VMDTAVRVTSEHYNHSH.....
Oncmyk MH1-C*01 AB162343 (V)THSLTH.FYTASSE VY. NFPEFMVVGMV DG VQMVHYDS N.. SQKAVPEQ....... DWMKQ...TDAEFWE..KERENFFYSQQ.SFKAEVATLKQHFNQSG.....
Oncmyk MH1-D*01 AY523666 (V)THSLTH.FYTASSD IP. NFPEFVFVGMV DG VQMVHYDS N.. IQKVVPEQ....... DWMKQ...TDAEFCE..KESENLFYSQQ.SFKAEVTTLKQHFNQSG.....
Oncmyk MH1-E AY525774 (D)HHSLKY.LYTAVSG DT. DFPEFTVVGLL DD QQFVHFGS N.. TKTLVNDA....... EWMNK...TGKYYND..LYKEPLINQYE.GFKNLITFAKKQFNQTQSK...
Oncmyk MH1-G AY253140 HSLRY.FYTTSSE IP. AFPEFVDMGMV ND QVISHYDS I.. TKRKVPKQ....... SWMETF..FDQQYWD..STTENLKSAES.IFKTNIQIAQKRFNQTG
Oncmyk MH1-H DQ091782 FYTVLPQ ST. GLPEFSAVTYL DE EPIYFYDS S.. TKEVVARQ....... EWVKEA..VDPDFWR..RNTQILKETEK.VLKNNMATARDRFNQT
G-ALPHA1-LIKE [D1] (RPI-MH1Like)
A AB B BC C CD D helix
(1-14) (18-28) (31-38) (42-49) (50-92B)
——————————————> ——————————> ———————> ———————> ———————————————————————————————————————————————————
1 7 10 14 18 21 28 31 38 42 45 49 50 54 61 68 72 74 80 92
0987654321 | .....|A..|...| ... |..|......| .. |......| ... |..|...|1234567 |...|ABC......|AB......|...|A.|.....|...........|AB
Homsap AZGP1 (AZGP1*01) (G)RYSLTY.IYTGLSK HVE DVPAFQALGSL ND LQFFRYNS K.. DRKSQPMG....... LWRQV...EGMEDWK..QDSQLQKARED.IFMETLKDIVEYYNDSN.....
Musmus AZGP1 (AZGP1*01) (G)SYSLTF.LYTGLSR PSK GFPRFQATAFL ND QAFFHYNS N.. SGKAEPVG....... PWSQV...EGMEDWE..KESQLQRAREE.IFLVTLKDIMDYYKDTT.....
Ratnor AZGP1 (AZGP1*01) (G)SYSLIF.LYTGLSR PSK GLPRFQATAFL ND QAFFHYNS N.. SGKAEPVE....... PWSHV...EGMEDWE..KESQLQRAREE.IFLVTLKDIMDYYEDST.....
Homsap CD1A (CD1A*01) (K)E PLSFHV.IWIASFY NH. SWKQNLVSGWL SD LQTHTWDS N.. SSTIVFLW....... PWSRGN..FSNEEWK..ELETLFRIRTI.RSFEGIRRYAHELQFE......
Homsap CD1B (CD1B*01) (Q)G PTSFHV.IQTSSFT NS. TWAQTQGSGWL DD LQIHGWDS D.. SGTAIFLK....... PWSKGN..FSDKEVA..ELEEIFRVYIF.GFAREVQDFAGDFQMK......
Homsap CD1C (CD1C*01) (Q)E HVSFHV.IQIFSFV NQ. SWARGQGSGWL DE LQTHGWDS E.. SGTIIFLH....... NWSKGN..FSNEELS..DLELLFRFYLF.GLTREIQDHASQDYSK......
Homsap CD1D L38817 (V)PQ R LFPLRC.LQISSFA NS. SWTRTDGLAWL GE LQTHSWSN D.. SDTVRSLK....... PWSQGT..FSDQQWE..TLQHIFRVYRS.SFTRDVKEFAKMLRLS......
Musmus CD1D (CD1D*01) (A)QQ K NYTFRC.LQMSSFA NR. SWSRTDSVVWL GD LQTHRWSN D.. SATISFTK....... PWSQGK..LSNQQWE..KLQHMFQVYRV.SFTRDIQELVKMMSPKED....
Ratnor CD1D (CD1D*01) (V)QQ . NYTFGC.LQISSFA NR. SWSRTDSVVWL GD LQTHRWSN D.. SDTISFTK....... PWSQGK..FSNQQWE..KLQHMFQVYRT.SFTRDIKEIVKMMSPKED....
Homsap CD1E (CD1E*01) (A)AE E QLSVRM.LQTSSFA NH. SWAHSEGSGWL GD LQTHGWDT V.. LGTIRFLK....... PWSHGN..FSKQELK..NLQSLFQLYFH.SFIQIVQASAGQFQLE......
Homsap EPCR (EPCR*01) (G)LQRCHM.LQISYFR DP. YHVWYQGNASL GG HLTHVLEG PDT NTTIIQLQ....... PL......QEPESWA..RTQSGLQSYLL.QFHGLVRLVHQERTLA......
Musmus EPCR (EPCR*01) (G)SQSLHM.LQISYFQ DH. HHVRHQGNASL GK LLTHTLEG PSQ NVTILQLQ....... PW......QDPESWE..RTESGLQIYLT.QFESLVKLVYRERKENVF....
Bostau EPCR (EPCR*01) D G PWDLHM.TQVSYFR NP. SQVWHRGNATL GG VLTHVLEG PGR NVSIQQLQ....... PL......QEPDSWA..LTKIYLNRYLE.EFVGLVQVVHQERGVT......
Homsap FCGRT (FCGRT*01) (E)S HLSLLY.HLTAVSS PAP GTPAFWVSGWL GP QQYLSYNS L.. RGEAEPCG....... AWVWEN..QVSWYWE..KETTDLRIKEK.LFLEAFKALGGK..........
Musmus FCGRT (FCGRT*01) (E)T RPPLMY.HLTAVSN PST GLPSFWATGWL GP QQYLTYNS L.. RQEADPCG....... AWVWEN..QVSWYWE..KETTDLKSKEQ.LFLEALKTLEKILN........
Ratnor FCGRT (FCGRT*01) (E)P RLPLMY.HLAAVSD LST GLPSFWATGWL GA QQYLTYNN L.. RQEADPCG....... AWIWEN..QVSWYWE..KETTDLKSKEQ.LFLEAIRTLENQIN........
Bostau FCGRT (FCGRT*01) (E)N YRSLQY.HFTAVSA PAA GTPAFWVSGWL GP QQYLSYNN L.. RAQAEPYG....... AWVWES..QVSWYWE..KETMDLRNQET.LFLEALQALGE...........
Homsap HFE (HFE*01) (R)SHSLHY.LFMGASE QDL GLSLFEALGYV DD QLFVFYDH E.. SRRVEPRT....... PWVSSR..ISSQMWL..QLSQSLKGWDH.MFTVDFWTIMENHNHSK.....
Musmus HFE (HFE*01) (R)SHSLRY.LFMGASE PDL GLPLFEARGYV DD QLFVSYNH E.. SRRAEPRA....... PWILEQ..TSSQLWL..HLSQSLKGWDY.MFIVDFWTIMGNYNHSK.....
Ratnor HFE (HFE*01) (G)SHSLRY.LFMGASK PDL GLPFFEALGYV DD QLFVSYNH E.. SRRAEPRA....... PWILGQ..TSSQLWL..QLSQSLKGWDY.MFIVDFWTIMGNYNHSK.....
Homsap MICA AL845443 (E)PHSLRY.NLTVLSW DGS VQSGFLTEVHL DG QPFLRCDR Q.. KCRAKPQG....... QWAEDV..LGNKTWD..RETRDLTGNGK.DLRMTLAHIKDQKE........
Homsap MICB AL663061 (E)PHSLRY.NLMVLSQ DGS VQSGFLAEGHL DG QPFLRYDR Q.. KRRAKPQG....... QWAENV..LGAKTWD..TETEDLTENGQ.DLRRTLTHIKDQKG........
Homsap MR1 (MR1*01) (R)THSLRY.FRLGVSD PIH GVPEFISVGYV DS HPITTYDS V.. TRQKEPRA....... PWMAEN..LAPDHWE..RYTQLLRGWQQ.MFKVELKRLQRHYNHS......
Musmus MR1 (MR1*01) (R)THSLRY.FRLAVSD PGP VVPEFISVGYV DS HPITTYDS V.. TRQKEPKA....... PWMAEN..LAPDHWE..RYTQLLRGWQQ.TFKAELRHLQRHYNHS......
Ratnor MR1 (MR1*01) (G)THSLRY.FRLAISD PGP GVPEFISVGYV DS HPITTYDS V.. TRQKEPRA....... PWMAEN..LAPDHWE..RYTQLLRGWQR.TFQTELRHLQRHYNHS......
Musmus RAE1B (RAE1B*01) (D)AHSLRC.NLTIKDP TPA DPLWYEAKCFV GE ILILHLSN I.. NKTMTSGD....... PGETA...NATEVKK..CLTQPLKNLCQ.KLRNKVSNTKVDTHKTN.....
Ratnor RAE1B (RAE1B*01) (D)IDSLRC.NLIVKSA IKP GQPWYEGPCSM NG KTLFQVTS L.. GKLTKE......... E.......NGTQACL..ILPQSLKNILE.LMRDHLLNMESEQIKTM.....
Musmus RAE1G (RAE1G*01) (D)AHSLRC.NLTIKAP TPA DPLWYEAKCLV DE ILILHLSN I.. NKTMTSGD....... PGETA...NATEVGE..CLTQPVNDLCQ.KLRDKVSNTKVDTHKTN.....
Ratnor RAE1G (RAE1G*01) (D)VHSLSC.NLIIRSP TKA EPLWYEGQCSM DG IDFLSSNN V.. NKTMPLGN....... QEKMA...NATEVWT..CLTQWIDRWKQ.ELRDKVSEIKVHTTKTS.....
Homsap RAET1E (RAET1E*01) (G)GHSLCF.NFTIKSL SRP GQPWCEAQVFL NK NLFLQYNS D.. NNMVKPLG....... LLGKKV..YATSTWG..ELTQTLGEVGR.DLRMLLCDIKPQIKTS......
Homsap RAET1H (RAET1H*01) (D)PHSLCY.DITVIPK FRP GPRWCAVQGQV DE KTFLHYDC G.. NKTVTPVS....... PLGKKL..NVTTAWK..AQNPVLREVVD.ILTEQLRDIQLENYTPK.....
Homsap RAET1I (RAET1I*01) (D)THCLCY.DFIITPK SRP EPQWCEVQGLV DE RPFLHYDC V.. NHKAKAFA....... SLGKKV..NVTKTWE..EQTETLRDVVD.FLKGQLLDIQVENLIPI.....
Homsap RAET1L (RAET1L*01) (D)PHSLCY.DITVIPK FRP GPRWCAVQGQV DE KTFLHYDC G.. NKTVTPVS....... PLGKKL..NVTMAWK..AQNPVLREVVD.ILTEQLLDIQLENYTPK.....
Homsap RAET1N (RAET1N*01) (D)AHSLWY.NFTIIHL PRH GQQWCEVQSQV DQ KNFLSYDC G.. SDKVLSMG....... HLEEQL..YATDAWG..KQLEMLREVGQ.RLRLELADTELEDFTPSG....
G-ALPHA [D1] (MH2)
A AB B BC C CD D helix
(1-14) (18-28) (31-38) (42-49) (50-92B)
——————————————> ——————————> ———————> ———————> ———————————————————————————————————————————————————
1 7 10 14 18 21 28 31 38 42 45 49 50 54 61 68 72 74 80 92
0987654321 | .....|A..|...| ... |..|......| .. |......| ... |..|...|1234567 |...|ABC......|AB......|...|A.|.....|...........|AB
Homsap MH2-PA1 (HLA-DPA1*0103) IK(A)DHVSTY.AAFVQTH ... .RPTGEFMFEF DE DEMFYVDL D.. KKETVWHL....... EEFGQ.......AFS..FEAQGGLANIA.ILNNNLNTLIQRSNHTQATN..
Homsap MH2-QA1 (HLA-DQA1*0501) IV(A)DHVASYGVNLYQSY ... .GPSGQYTHEF DG DEQFYVDL G.. RKETVWCL....... PVLRQ.......FR...FDPQFALTNIA.VLKHNLNSLIKRSNSTAATN..
Homsap MH2-RA (HLA-DRA*0101) IK(E)EHVIIQ.AEFYLNP ... .DQSGEFMFDF DG DEIFHVDM A.. KKETVWRL....... EEFGR.......FAS..FEAQGALANIA.VDKANLEIMTKRSNYTPITN..
Homsap MH2-MA (HLA-DMA*01) (A)PTPMWPDDL Q NHTFLH.TVYCQDG ... .SPSVGLSEAY DE DQLFFFDF S.. QNTRVPRL....... PEFAD.......WAQEQGDAPAILFDKE.FCEWMIQQIGPKLDGKIPVSR.
Homsap MH2-OA (HLA-DOA*01) TK(A)DHMGSYGPAFYQSY ... .GASGQFTHEF DE EQLFSVDL K.. KSEAVWRL....... PEFGD.......FAR..FDPQGGLAGIA.AIKAHLDILVERSNRSRAIN..
Musmus MH2-AA (H2-AA*01) (A)DHVGTYGISVYQSP ... .GDIGQYTFEF DG DELFYVDL D.. KKETVWML....... PEFGQ.......LAS..FDPQGGLQNIA.VVKHNLGVLTKRSNSTPATN..
Musmus MH2-EA (H2-EA*02) IK(E)EHTIIQ.AEFYLLP ... .DKRGEFMFDF DG DEIFHVDI E.. KSETIWRL....... EEFAK.......FAS..FEAQGALANIA.VDKANLDVMKERSNNTPDAN..
Musmus MH2-MA (H2-DMA*01) (A)STPVFWDDP Q NHTFRH.TLFCQDG ... .IPNIGLSETY DE DELFSFDF S.. QNTRVPRL....... PDFAE.......WAQGQGDASAIAFDKS.FCEMLMREVSPKLEGQIPVSR.
Musmus MH2-OA (H2-DOA*01) IK(A)DHMGSYGPAFYQSY ... .DASGQFTHEF DG EQIFSVDL K.. NEEVVWRL....... PEFGD.......FAH..SDFQSGLMSIS.MIKAHLDILVERSNRTRAVS..
Oncmyk MH2-DA*01 AJ251433 (E)DKVLHIDLAITGCS ... .DSDGVDMYGL DG EELWYADF N.. KKEGVMAL....... PPFAD.......QMT..FPGFYEQAVGN.LGICKANLAVAIKASKNPP...
G-ALPHA2 [D2] (MH1)
A AB B BC C CD D helix
(1-14) (18-28) (31-38) (42-49) (50-92B)
——————————————> ——————————> ———————> ———————> ———————————————————————————————————————————————————
1 7 10 14 18 21 28 31 38 42 45 49 50 54 61 68 72 74 80 92
0987654321 | .....|A..|...| ... |..|......| .. |......| ... |..|...|1234567 |...|ABC......|AB......|...|A.|.....|...........|AB
Homsap MH1-A (HLA-A*0201) (G)SHTVQR.MYGCDVG SDW RFLRGYHQYAY DG KDYIALKE D.. LRSWTAAD....... MAAQT...TKHKWEAA.HVAEQLRAYLEGTCVEWLRRYLENGKETLQRT..
Homsap MH1-B (HLA-B*0702) (G)SHTLQS.MYGCDVG PDG RLLRGHDQYAY DG KDYIALNE D.. lRSWTAAD....... TAAQI...TQRKWEAA.REAEQRRAYLEGECVEWLRRYLENGKDKLERA..
Homsap MH1-C (HLA-C*0701) (G)SHTLQR.MYGCDLG PDG RLLRGYDQSAY DG KDYIALNE D.. LRSWTAAD....... TAAQI...TQRKLEAA.RAAEQLRAYLEGTCVEWLRRYLENGKETLQRA..
Homsap MH1-E (HLA-E*01) (G)SHTLQW.MHGCELG PDR RFLRGYEQFAY DG KDYLTLNE D.. LRSWTAVD....... TAAQI...SEQKSNDA.SEAEHQRAYLEDTCVEWLHKYLEKGKETLLHL..
Homsap MH1-F (HLA-F*01) (G)SHTLQG.MNGCDMG PDG RLLRGYHQHAY DG KDYISLNE D.. LRSWTAAD....... TVAQI...TQRFYEAE.EYAEEFRTYLEGECLELLRRYLENGKETLQRA..
Homsap MH1-G (HLA-G*01) (S)SHTLQW.MIGCDLG SDG RLLRGYEQYAY DG KDYLALNE D.. LRSWTAAD....... TAAQI...SKRKCEAA.NVAEQRRAYLEGTCVEWLHRYLENGKEMLQRA..
Musmus MH1-D1 (H2-D1*02) (G)SHTLQQ.MSGCDLG SDW RLLRGYLQFAY EG RDYIALNE D.. LKTWTAAD....... MAAQI...TRRKWEQS.GAAEHYKAYLEGECVEWLHRYLKNGNATLLRT..
Musmus MH1-K1 (MH1-K1*01) (G)SHTIQV.ISGCEVG SDG RLLRGYQQYAY DG CDYIALNE D.. LKTWTAAD....... MAALI...TKHKWEQA.GEAERLRAYLEGTCVEWLRRYLKNGNATLLRT..
Musmus MH1-L (H2-L*02) (G)THTLQW.MYGCDVG SDG RLLRGYEQFAY DG RDYIALNE D.. LKTWTAAD....... MAAQI...TRRKWEQA.GAAEYYRAYLEGECVEWLHRYLKNGNATLLRT..
Musmus MH1-M5 (H2-M5*02) (G)SHVFQC.VYGCEVG PDG LFLRGHEKHAY DG RDYLTLSP D.. LHSWVAGD....... TAAQI...TLRRWEKS.GVSEQRQSFLKGECVDSLRTYLEIRKETLLRT..
Musmus MH1-Q7 (H2-Q7*02) (G)SHTLQW.MYGCDMG SDG RLLRGYLQFAY EG RDYIALNE D.. LKTWTAVD....... MAAQI...TRRKWEQA.GIAEKDQAYLEGTCMQSLRRYLQLGKETLLRT..
Musmus MH1-T3 (H2-T3*01) (G)SHTIQV.MYGCEVE FFG SLFRAYEQHGY DG RDYIALNE D.. LKTWTAAD....... TAAEI...TRSKWEQA.GYTELRRTYLEGPCKDSLLRYLENRKKTQECT..
Ratnor MH1-A (RT1-A) (G)SHTIQE.MYGCDVG SDG SLLRGYRQDAY DG RDYIALNE D.. LKTWTAAD....... FAAQI...TRNKWERA.RYAERLRAYLEGTCVEWLSRYLELGKETLLRS..
Ambmex MH1-A (AMME-IA) (G)LHTVQQ.MYGCELR GD. GSIGGFMQYAY DG GDFLSFDK D.. RMRYIATA....... PPAQV...SVDRLNSEKIQAQRQKAYLEGECIEWLQKYLQYGEETLLRR..
Saltru MH1-A (G)VHTWVN.MYGCEWD EDT GVTGGFMQYGY DG EDFVAFDL D.. TKTWIAPT....... PQSFI...TKQKWERDITLNEQNKHYLTQTCIEWLKKYLDYGKSTLMRT..
Onckis MH1-A (H)DHFYQA.HGRCGWK SD. GTTEAFMSHAY DG KDFVSFDV S.. TRTWTAAV....... SHAVF...YKRKRETDLEDLVRLVIHYESGCIRWLEKLLEFSVTVREPK..
Oncmyk MH1-A*01 AB162342 (G)VHTFQL.MYGCELG DD. GITRGDFQLGY DG ADFLSLDK S.. TLTWTAAN....... QKAVI...TKLKWDATGAEANFQKNYLENTCIEWLKKYVNYGKDTLERK..
Oncmyk MH1-B*01 AF091779 (D)HFYQA.HGRCGWK SD. GTTEAFMSHAY DG KDFVSFDV S.. TRTWTAAV....... SHAVF...YKRKRETDLEDLVRLVIHYESGCIRWLEKLLEFSVTVREPK..
Oncmyk MH1-C*01 AB162343 (G)VHILQY.MYGCSRD DET EQTEGFGQLGY NG ENFLEYDM K.. TLTWKSRK....... QQANF...MQDEWNSDISRLGFWKIYFSQTCIECLKKQVDNGKRTLRRT..
Oncmyk MH1-D*01 AY523666 (G)VHILQY.MYGCSRD DET EQTEGFGQLGY NG ENFLEYDM K.. TLTWKSLK....... QQPNF...MQDEWNSDTSRLLFWKNYFTQTCIECLKKQVDNRKSTLMRT..
Oncmyk MH1-E AY525774 (G)VHTIQN.LYGCEWN DET ELQDYFHHYGY DG EDFISLDM K.. TVRWITSV....... QQADT...IKQKWDDNSKDLHYLKWYFTKECIDTLKKYVDFASSVLKKI..
Oncmyk MH1-G AY253140 (G)IHISQD.MYGCTWD DET GFTEGFHHIGY DG QDLLTFDV K.. TATWIALV....... PQALH...SKMKWEMDLSGIKSKKSYLTQDCIEWLKKYLDYGKTTLQRT..
Oncmyk MH1-H DQ091789 WV EEGATEEQYGY GG EDFLLFDL K.. NERWIAPV....... RQGHI...TKIKWDANVPKLKAKIHYLTHT
G-ALPHA2-LIKE [D2] (RPI-MH1Like)
A AB B BC C CD D helix
(1-14) (18-28) (31-38) (42-49) (50-92B)
——————————————> ——————————> ———————> ———————> ———————————————————————————————————————————————————
1 7 10 14 18 21 28 31 38 42 45 49 50 54 61 68 72 74 80 92
0987654321 | .....|A..|...| ... |..|......| .. |......| ... |..|...|1234567 |...|ABC......|AB......|...|A.|.....|...........|AB
Homsap AZGP1 (AZGP1*01) (G)SHVLQG.RFGCEIE NN. RSSGAFWKYYY DG KDYIEFNK E.. IPAWVPFD....... PAAQI...TKQKWEAEPVYVQRAKAYLEEECPATLRKYLKYSKNILDRQ..
Musmus AZGP1 (AZGP1*01) (G)SHTFQG.MFGCEIT NN. RSSGAVWRYAY DG EDFIEFNK E.. IPAWIPLD....... PAAAN...TKLKWEAEKVYVQRAKAYLEEECPEMLKRYLNYSRSHLDRI..
Ratnor AZGP1 (AZGP1*01) (G)SHTFQG.MFGCEIT NN. RSSGAVWRYAY DG EDFIEFNK E.. IPAWIPLD....... PAAAN...TKLKWEAEKVYVQRAKAYLEEECPTMLKKYLTYSRSHLDRT..
Homsap CD1A (CD1A*01) (Y)PFEIQV.TGGCELH SG. KVSGSFLQLAY QG SDFVSFQN ... .NSWLPYPVAG.... NMAKH...FCKVLNQNQHENDITHNLLSDTCPRFILGLLDAGKAHLQRQ..
Homsap CD1B (CD1B*01) (Y)PFEIQG.IAGCELH SG. GAIVSFLRGAL GG LDFLSVKN ... .ASCVPSPEGG.... SRAQK...FCALIIQYQGIMETVRILLYETCPRYLLGVLNAGKADLQRQ..
Homsap CD1C (CD1C*01) (Y)PFEVQV.KAGCELH SG. KSPEGFFQVAF NG LDLLSFQN ... .TTWVPS........ PLAQS...VCHLLNQYEGVTETVYNLIRSTCPRFLLGLLDAGKMYVHRQ..
Homsap CD1D L38816 (Y)PLELQV.SAGCEVH PG. NASNNFFHVAF QG KDILSFQG ... .TSWEPTQEAP.... LWVNL...AIQVLNQDKWTRETVQWLLNGTCPQFVSGLLESGKSELKKQ..
Musmus CD1D (CD1D*01) (Y)PIEIQL.SAGCEMY PG. NASESFLHVAF QG KYVVRFWG ... .TSWQTVPGAP.... SWLDL...PIKVLNADQGTSATVQMLLNDTCPLFVRGLLEAGKSDLEKQ..
Ratnor CD1D (CD1D*01) (Y)PIEVQL.SAGCEMY PG. NASESFLHVAF QG EYVVRFHG ... .TSWQKV........ PWLDL...PIKMLNADEGTRETVQILLNDTCPQFVRGLLEAGKPDLEKQ..
Homsap CD1E (CD1E*01) (Y)PFEIQI.LAGCRMN ... .APQIFLNMAY QG SDFLSFQG ... .ISWEPS........ PRAQN...ICKVLNRYLDIKEILQSLLGHTCPRFLAGLMEAGESELKRK..
Homsap EPCR (EPCR*01) (F)PLTIRC.FLGCELP PEG SRAHVFFEVAV NG SSFVSFRP E.. RALWQADT....... QVVTF...TLQQLNAYNRTRYELREFLEDTCVQYVQKHISAENTK......
Musmus EPCR (EPCR*01) (F)PLTVSC.SLGCELP EEG SEPHVFFDVAV NG SAFVSFRP K.. TAVWVSGS....... .AANF...TLKQLNAYNRTRYELQEFLQDTCVEFLENHITTQNMK......
Bostau EPCR (EPCR*01) (F)PLIIRC.FLGCELP PEG SEAHVFFEVAV NG SSFVNFQP K.. TASWVAEP....... .VVTY...TVDQLNKYNRTRYELREFLQDTCVQYIQKHITTNNLK......
Homsap FCGRT (FCGRT*01) (G)PYTLQG.LLGCELG PD. NTSVPTAKFAL NG EEFMNFDL K.. QGTWGGDW....... PEALA...ISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWK..
Musmus FCGRT (FCGRT*01) (G)TYTLQG.LLGCELA SD. NSSVPTAVFAL NG EEFMKFNP R.. IGNWTGEW....... PETEI...VANLWMKQPDAARKESEFLLNSCPERLLGHLERGRRNLEWK..
Ratnor FCGRT (FCGRT*01) (G)TFTLQG.LLGCELA PD. NSSLPTAVFAL NG EEFMRFNP R.. TGNWSGEW....... PETDI...VGNLWMKQPEAARKESEFLLTSCPERLLGHLERGRQNLEWK..
Bostau FCGRT (FCGRT*01) (G)PFTMQG.LLGCELG PD. NVSVPVAKFAL NG EEFMMFDP K.. LGIWDGDW....... PESRT...VSIKWTQQPEAVNKEKTFLLYSCPHRLLGHLERGRGNLEWK..
Homsap HFE (HFE)*01 (E)SHTLQV.ILGCEMQ ED. NSTEGYWKYGY DG QDHLEFCP D.. TLDWRAAE....... PRAWP...TKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQ..
Musmus HFE (HFE*01) (E)SHILQV.VLGCEVH ED. NSTSGFWRYGY DG QDHLEFCP K.. TLNWSAAE....... PGAWA...TKVEWDEHKIRAKQNRDYLEKDCPEQLKRLLELGRGVLGQQ..
Ratnor HFE (HFE*01) (E)SHILQV.ILGCEVH ED. NSTSGFWKYGY DG QDHLEFCP K.. TLNWSAAE....... PRAWA...TKMEWEEHRIRARQSRDYLQRDCPQQLKQVLELQRGVLGQQ..
Homsap MICA AL845443 (G)LHSLQE.IRVCEIH ED. NSTRSSQHFYY DG ELFLSQNL E.. TKEWTMPQSSRAQ.. TLAMN...VRNFLKEDAMKTKTHYHAMHADCLQELRRYLKSGV.VLRRT..
Homsap MICB AL663061 (G)LHSLQE.IRVCEIH ED. SSTRGSRHFYY DG ELFLSQNL E.. TQESTVPQSSRAQ.. TLAMN...VTNFWKEDAMKTKTHYRAMQADCLQKLQRYLKSGV.AIRRT..
Homsap MR1 (MR1*01) (G)SHTYQR.MIGCELL ED. GSTTGFLQYAY DG QDFLIFNK D.. TLSWLAVD....... NVAHT...IKQAWEANQHELLYQKNWLEEECIAWLKRFLEYGKDTLQRT..
Musmus MR1 (MR1*01) (G)LHTYQR.MIGCELL ED. GSTTGFLQYAY DG QDFIIFNK D.. TLSWLAMD....... YVAHI...TKQAWEANLHELQYQKNWLEEECIAWLKRFLEYGRDTLERT..
Ratnor MR1 (MR1*01) (G)LHTYQR.MIGCELL ED. GSTTGFLQYAY DG QDFIVFDK D.. TLSWLAMD....... NVAHI...TKRAWEANLHELQYQKNWLEEECIAWLKRFLEYGSDALERT..
Musmus RAE1B (RAE1B*01) (G)YPHLQV.TMIYPQS QG. RTPSATWEFNI SD SYFFTFYT E.. NMSWRSAN....... DESGV...IMNKWKDDGEFVKQLKFLIH.ECSQKMDEFLKQSKEKPRST..
Ratnor RAE1B (RAE1B*01) (G)NNTFQV.TMQSQYN KG. QLIDAFCNLTV DG ...LATDG Q.. SSFHYNPT....... KDNWR...GSGQWERNRELKKGLQMMLMGDFGHCYEELLTLSGETPRLS..
Musmus RAE1G (RAE1G*01) (G)YPHLQV.TMIYPQS QG. QTPSATWEFNI SD SYFFTFYT E.. NMSWRSAN....... DESGV...IMNKWNDDGDLVQRLKYFIP.ECRQKIDEFLKQSKEKPRST..
Ratnor RAE1G (RAE1G*01) (G)HPTLRV.TMLSKHS HE. QIIGASWEFNT SE NYSFILDL K.. TMKWKLIN....... PVPGD...IMKEWKDDETLMKHLNLSIA.ECSKKFNEFLNQHEERTMVQ..
Homsap RAET1E (RAET1E*01) (D)PSTLQV.EMFCQRE AE. RCTGASWQFAT NG EKSLLFDA M.. NMTWTVIN....... HEASK...IKETWKKDRGLEKYFRKLSKGDCDHWLREFLGHWEAMPEPT..
Homsap RAET1H (RAET1H*01) (E)PLTLQA.RMSCEQK AE. GHSSGSWQFSF DG QIFLLFDS E.. KRMWTTVH....... PGARK...MKEKWENDKVVAMSFHYFSMGDCIGWLEDFLMGMDSTLEPSAG
Homsap RAET1I (RAET1I*01) (E)PLTLQA.RMSCEHE AH. GHGRGSWQFLF NG QKFLLFDS N.. NRKWTALH....... PGAKK...MTEKWEKNRDVTMFFQKISLGDCKMWLEEFLMYWEQMLDPT..
Homsap RAET1L (RAET1L*01) (E)PLTLQA.RMSCEQK AE. GHSSGSWQFSI DG QTFLLFDS E.. KRMWTTVH....... PGARK...MKEKWENDKDVAMSFHYISMGDCIGWLEDFLMGMDSTLEPSAG
Homsap RAET1N (RAET1N*01) (G)PLTLQV.RMSCECE AD. GYIRGSWQFSF DG RKFLLFDS N.. NRKWTVVH....... AGARR...MKEKWEKDSGLTTFFKMVSMRDCKSWLRDFLMHRKKRLEPT..
G-BETA [D1] (MH2)
A AB B BC C CD D helix
(1-14) (18-28) (31-38) (42-49) (50-92B)
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1 7 10 14 18 21 28 31 38 42 45 49 50 54 61 68 72 74 80 92
0987654321 | .....|A..|...|A... |..|......| .. |......| ... |..|...|1234567 |...|ABC......|AB......|...|A.|.....|...........|AB
Homsap MH2-PB1 (HLA-DPB1*0401) (E)NYLFQG.RQECYAF NGT Q..RFLERYIY NR EEFARFDS D.. VGEFRAVT....... ELGRP...AAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTLQRR.....
Homsap MH2-QB1 (HLA-DQB1*0301) (E)DFVYQF.KAMCYFT NGT ERVRYVTRYIY NR EEYARFDS D.. VEVYRAVT....... PLGPP...DAEYWNSQKEVLERTRAELDTVCRHNYQLELRTTLQRR.....
Homsap MH2-RB1 (HLA-DRB1*1402) (P)RFLEYS.TSECHFF NGT ERVRFLERYFH NQ EENVRFDS D.. VGEYRAVT....... ELGRP...DAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTVQRR.....
Homsap MH2-MB1 (HLA-DMB1*01) (G)GFVAHV.ESTCLLD DAG TPKDFTYCISF NK DLLTCWDP E.. ENKMAPCEFGVL... NSLAN...VLSQHLNQKDTLMQRLRNGLQNCATHTQPFWGSLTNRT.....
Homsap MH2-OB (HLA-DOB*01) (E)DFVIQA.KADCYFT NGT EKVQFVVRFIF NL EEYVRFDS D.. VGMFVALT....... KLGQP...DAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRK.....
Musmus MH2-AB (H2-AB*02) (R)HFVHQF.QPFCYFT NGT QRIRLVIRYIY NR EEYVRFDS D.. VGEYRAVT....... ELGRP...DAEYWNK..QYLERTRAELDTVCRHNYEKTETPTSLRRL....
Musmus MH2-EB1 (H2-EB1*01) (P)WFLEYC.KSECHFY NGT QRVRLLERYFY NL EENLRFDS D.. VGEFRAVT....... ELGRP...DAENWNSQPEFLEQKRAEVDTVCRHNYEISDKFLVRRR.....
Musmus MH2-MB1 (H2-DMB1*02) (G)GFVAHV.ESTCVLD DAG TPQDFTYCVSF NK DLLACWDP I.. VGKIVPCEFGVL... YPLAE...NFSRILNKEESLLQRLQNGLPDCASHTQPFWNALTHRT.....
Musmus MH2-OB (H2-DOB*01) (E)NFVIQA.KADCYFT NGT EKVHLLVRFIF NL EEYLHFDS D.. LGMFVALT....... ELGEP...DADQWNKRLDLLETSRAAVNMVCRQKYKLGAPFTVERN.....
Oncmyk MH2-DB1*01 U20943 (D)GYFEQV.VRQCRYSSKDL HGIEFIDSYVF NK AEHVRFNS T.. VGRYVGYT....... EHGLK...NAEAWNSDAGILGQEQAELERYCKPSAAIDYSAILDKT.....
Oncmyk MH2-DB2*01 AF115529 (D)GYASDV.VTRCLYSSIDM HGAEFIQSYTF NK VEHLRFNS T.. VGEFVGYT....... ELGLK...NAKRLNRGQEVV.QMRGELERLCKPNADIHYRAILDKT.....