1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 Q P V L H Q P P A M S S A L G T T I R S74019 VPREB1*01 F V-LIKE gDNA cag ccg gtg ctg cat cag ccg ccg gcc ... atg tcc tcg gcc ctt gga acc aca atc cgc D86992 VPREB1*01 F V-LIKE gDNA --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- D88270 VPREB1*01 F V-LIKE gDNA --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- M34927 VPREB1*02 F V-LIKE gDNA --- --- --- --a --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- ____________________BC-LOOP_____________________ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 L T C T L R N D H D I G V Y S V Y S74019 VPREB1*01 F V-LIKE gDNA ctc acc tgc acc ctg agg aac gac cat gac atc ... ... ... ggt gtg tac agc gtc tac D86992 VPREB1*01 F V-LIKE gDNA --- --- --- --- --- --- --- --- --- --- --- ... ... ... --- --- --- --- --- --- D88270 VPREB1*01 F V-LIKE gDNA --- --- --- --- --- --- --- --- --- --- --- ... ... ... --- --- --- --- --- --- M34927 VPREB1*02 F V-LIKE gDNA --- --- --- --- --- --- --- --- --- --- --- ... ... ... --- --- --- --- --- --- _______________C'C"- 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 W Y Q Q R P G H P P R F L L R Y F S Q S74019 VPREB1*01 F V-LIKE gDNA tgg tac cag cag agg ccg ggc cac cct ccc agg ttc ctg ctg aga tat ttc tca caa ... D86992 VPREB1*01 F V-LIKE gDNA --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... D88270 VPREB1*01 F V-LIKE gDNA --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... M34927 VPREB1*02 F V-LIKE gDNA --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... LOOP________________ 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 S D K S Q G P Q V P P R F S G S K S74019 VPREB1*01 F V-LIKE gDNA ... ... tca gac aag agc cag ggc ccc cag gtc ccc ... cct cgc ttc tct gga tcc aaa D86992 VPREB1*01 F V-LIKE gDNA ... ... --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- D88270 VPREB1*01 F V-LIKE gDNA ... ... --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- M34927 VPREB1*02 F V-LIKE gDNA ... ... --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 D V A R N R G Y L S I S E L Q P E D E A S74019 VPREB1*01 F V-LIKE gDNA gat gtg gcc agg aac agg ggg tat ttg agc atc tct gag ctg cag cct gag gac gag gct D86992 VPREB1*01 F V-LIKE gDNA --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- D88270 VPREB1*01 F V-LIKE gDNA --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- M34927 VPREB1*02 F V-LIKE gDNA --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ______________________FG-STRAND_______________________ 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 M Y Y C A M G A R S S E K E E R E R E W S74019 VPREB1*01 F V-LIKE gDNA atg tat tac tgt gct atg ggg gcc cgc agc tcg gag aag gag gag agg gag agg gag tgg D86992 VPREB1*01 F V-LIKE gDNA --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- D88270 VPREB1*01 F V-LIKE gDNA --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- M34927 VPREB1*02 F V-LIKE gDNA --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- 121 122 123 124 125 126 127 128 129 130 131 132 133 134 E E E M E P T A A R T R V P S74019 VPREB1*01 F V-LIKE gDNA gag gaa gaa atg gaa ccc act gca gcc agg aca cgt gtc cct D86992 VPREB1*01 F V-LIKE gDNA --- --- --- --- --- --- --- --- --- --- --- --- --- --- D88270 VPREB1*01 F V-LIKE gDNA --- --- --- --- --- --- --- --- --- --- --- --- --- --- M34927 VPREB1*02 F V-LIKE gDNA --- --- --- --- --- --- --- ---