By homology with the IG and TR V-DOMAINs, the limits of the putative CDR3-IMGT are shown.
___________________________________________________________________________________________________________________________________ Accession Allele number name ___________________________________________________________________________________________________________________________________ 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 Q P M V H Q P P L A S S S L G A T I R X05557 , VPREB1*01 CAG CCC ATG GTG CAT CAG CCA CCA TTA ... GCA TCT TCT TCC CTT GGA GCC ACC ATC CGC X05556 , VPREB1*01 (cDNA) --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- ___________________CDR1-IMGT____________________ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 L S C T L S N D H N I G I Y S I Y X05557 , VPREB1*01 CTC TCC TGT ACC CTG AGC AAC GAC CAT AAC ATT GGC ATT TAC AGC ... ... ... ATT TAC X05556 , VPREB1*01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... --- --- _______________CDR2- 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 W Y Q Q R P G H P P R F L L R Y F S H S X05557 , VPREB1*01 TGG TAC CAG CAG AGG CCG GGC CAC CCT CCC AGG TTC CTG CTG AGA TAC TTC TCA CAC TCA X05556 , VPREB1*01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- IMGT________________ 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 D K H Q G P D I P P R F S G S K X05557 , VPREB1*01 GAC AAG ... ... ... CAC CAG GGT CCC GAT ATC CCA ... CCT CGC TTC TCC GGG TCC AAA X05556 , VPREB1*01 --- --- ... ... ... --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 D T T R N L G Y L S I S E L Q P E D E A X05557 , VPREB1*01 GAT ACG ACC AGG AAC CTG GGG TAT CTG AGC ATC TCT GAA CTG CAG CCT GAG GAC GAG GCT X05556 , VPREB1*01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- _______________________CDR3-IMGT_______________________ 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 V Y Y C A V G L R S Q E K K R M E R E W X05557 , VPREB1*01 GTG TAT TAC TGT GCC GTG GGG CTC CGG AGC CAG GAA AAG AAG AGG ATG GAG AGG GAG TGG X05556 , VPREB1*01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- 121 122 123 124 125 126 127 128 129 130 131 E G E K S Y T D L G S * X05557 , VPREB1*01 GAA GGA GAA AAG TCG TAT ACA GAT TTG GGA TCT X05556 , VPREB1*01 --- --- --- --- --- --- --- --- --- --- ---