IMGT Repertoire (RPI)

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Other FCGR entries

Homo sapiens: FCGR1A, FCGR1C, FCGR2A, FCGR2B, FCGR3B
Mus musculus: FCGR1

IMGT RPI entry from gene to protein for Homo sapiens FCGR1B

Citing IMGT RPI entry for FCGR1B

Duprat, E. et al. IMGT standardization for alleles and mutations of the V-LIKE-DOMAINs and C-LIKE-DOMAINs of the immunoglobulin superfamily, Recent Research Developments in Human Genetics, 2, 111-136 (2004)

with permission from Research Signpost

IMGT gene name and definition

IMGT gene name: Homo sapiens FCGR1B
IMGT gene definition: Fc fragment of IgG, high affinity Ib, Receptor for(CD64)

Chromosomal localization

Chromosome: 1
Chromosomal localization: 1p12

Gene exon/intron organization

Legend:

Length of the exons and introns are in base pairs.
Colors are according to IMGT Color menu for regions and domains

Number of alleles: 2

IMGT reference alleles

Allele name	Gene functionality	IMGT reference sequences
Allele name	Gene functionality	Clone names	Accession numbers	Molecule type
FCGR1B*01	F		M91646 (1)	gDNA
FCGR1B*02			L03420 (2)	cDNA splicing C 1

IMGT reference sequences (in FASTA format) for the allele(s): FCGR1B*01 to FCGR1B*02

Nucleotide sequence in FASTA format with gaps according to the IMGT unique numbering
Amino acid sequence in FASTA format with gaps according to the IMGT unique numbering
Nucleotide sequence in FASTA format without gaps
Amino acid sequence in FASTA format without gaps

Other sequences from the literature

Allele name	Gene functionality	IMGT reference sequences
Allele name	Gene functionality	Clone names	Accession numbers	Molecule type
FCGR1B*01	F		L03419[2]/TrEMBL: Q92637	cDNA splicing B (2)

Corresponding protein database accession numbers

Allele name	Accession numbers		Number of amino acids	Protein isoform
Allele name	Nucleotide databases	Protein databases	Number of amino acids	Protein isoform
FCGR1B*01	M91646		224 aa
FCGR1B*01	L03419	Tr: Q92637	280 aa
FCGR1B*02	L03420	Tr: Q92638	188 aa

IMGT notes:

(1) No EX2, EX3 and EX5 .
(2) No EX5.
(3) STOP-CODON in EX5[D3](c115>t,Q39>*), according to the IMGT unique numbering for C-DOMAIN and C-LIKE-DOMAIN.

IMGT references:

[1] Ernst, L.K. et al, J. Biol. Chem., 267, 15692-15700 (1992). PMID:1379234
[2] Porges, A.J. et al, J. Clin. Invest., 90, 2102-2109 (1992). PMID:1430234

Genomic sequence

Genomic sequence from M91646

Coding region sequence

The coding region (CODING-REGION) sequence starts from INIT-CODON (or its encoded amino acid) to STOP-CODON (not included).
The nucleotide sequence is extracted from cDNA (c) sequences and/or is built by artificial exon joining from genomic DNA (g) sequences. The amino acid sequence is the translation of the nucleotide sequence.

FCGR1B*01: M91646(g)

Nucleotide sequence

1        atgtggttct tgacaactct gctcctttgg gttccagttg atgggcaagt ggacaccaca

61       aaggcagtga tcactttgca gcctccatgg gtcagcgtgt tccaagagga aaccgtaacc

121      ttgcactgtg aggtgctcca tctgcctggg agcagctcca cacagtggtt tctcaatggc

181      acagccactc agacctcgac ccccagctac agaatcacct ctgccagtgt caatgacagt

241      ggtgaataca ggtgccagag aggtctctca gggcgaagtg accccataca gctggaaatc

301      cacagaggct ggctactact gcaggtctcc agcagagtct tcatggaagg agaacctctg

361      gccttgaggt gtcatgcgtg gaaggataag ctggtgtaca atgtgcttta ctatcgaaat

421      ggcaaagcct ttaagttttt ccactggaat tctaacctca ccattctgaa aaccaacata

481      agtcacaatg gcacctacca ttgctcaggc atgggaaagc atcgctacac atcagcagga

541      atatcacaat acactgtgaa agagctattt ccagctccag tgctgaatgc atctgtgaca

601      tccccactcc tggaggggaa tctggtcacc ctgagctgtg aaacaaagtt gctcttgcag

661      aggcctggtt tgtagcttta cttctccttc tacatgggca gcaagaccct gcgaggcagg

721      aacacatcct ctgaatacca aatactaact gctagaagag aagactctgg gttatactgg

781      tgcgaggctg ccacagagga tggaaatgtc cttaagcaca gccctgagtt ggagcttcaa

841      gtgcttggcc tccagttacc aactcctgtc tggtttcatg tccttttcta tctggcagtg

901      ggaataatgt ttttagtgaa cactgttctc tgggtgacaa tacgtaaaga actgaaaaga

961      aagaaaaagt ggaatttaga aatctctttg gattctggtc atgagaagaa ggtaatttcc

1021     agccttcaag aagacagaca tttagaagaa gagctgaaat gtcaggaaca aaaagaagaa

1081     cagctgcagg aaggggtgca ccggaaggag ccccaggggg ccacgtag

Nucleotide sequence in FASTA format (without gaps) FCGR1B*01

Amino acid sequence

1        MWFLTTLLLW VPVDGQVDTT KAVITLQPPW VSVFQEETVT LHCEVLHLPG SSSTQWFLNG

61       TATQTSTPSY RITSASVNDS GEYRCQRGLS GRSDPIQLEI HRGWLLLQVS SRVFMEGEPL

121      ALRCHAWKDK LVYNVLYYRN GKAFKFFHWN SNLTILKTNI SHNGTYHCSG MGKHRYTSAG

181      ISQYTVKELF PAPVLNASVT SPLLEGNLVT LSCETKLLLQ RPGL*LYFSF YMGSKTLRGR

241      NTSSEYQILT ARREDSGLYW CEAATEDGNV LKHSPELELQ VLGLQLPTPV WFHVLFYLAV

301      GIMFLVNTVL WVTIRKELKR KKKWNLEISL DSGHEKKVIS SLQEDRHLEE ELKCQEQKEE

361      QLQEGVHRKE PQGAT*

Amino acid sequence in FASTA format (without gap) FCGR1B*01

Legend:

Colors are according to IMGT Color menu for regions and domains
Nucleotide and amino acid letters (in bold) in purple, green or blue are according to IMGT Color menu for splicing types.

IMGT links

IMGT Repertoire

Chromosomal localization:
Alignment of alleles:
Protein displays: C-LIKE-DOMAIN
IMGT Collier de perles: C-LIKE-DOMAIN

External links

Genome databases

Entrez Gene: 2210
GENATLAS: 721
GeneCards: FCGR1B
GDB: 135923
OMIM: 601502

Sequence databases

EMBL: M91646
GenBank: M91646
DDBJ: M91646
Swiss-Prot:
TrEMBL: Q92637
NCBI:

Structure database

PDB: