Other B7 Family entries

IMGT RPI entry from gene to protein for Mus musculus B7H4

Citing IMGT RPI entry for B7H4

Duprat, E. et al. IMGT standardization for alleles and mutations of the V-LIKE-DOMAINs and C-LIKE-DOMAINs of the immunoglobulin superfamily, Recent Research Developments in Human Genetics, 2, 111-136 (2004) pdf with permission from Research Signpost

IMGT gene name and definition

Chromosomal localization

Gene exon/intron organization

B7H4 Gene exon/intron organization

Legend:

Number of alleles: 3

IMGT reference alleles

Allele names Gene functionality IMGT reference sequences
Exons Accession numbers Molecule type
B7H4*01 F EX1-5 AY322147 [1] cDNA
B7H4*02 F EX1-5 AK143276 cDNA (1)
B7H4*03 F EX1-5 BC032925 cDNA (2)

IMGT reference sequences (in FASTA format) for the allele(s): B7H4*01 to B7H4*03

Other sequences from the literature

Allele names Gene functionality IMGT reference sequences
Exons Accession numbers Molecule type
B7H4*01 F EX1-5 AK145664 cDNA
AY280973 cDNA
AY346099 cDNA
NM_178594 cDNA

Corresponding protein database accession numbers

Allele name Accession numbers Number of amino acids Protein isoform
Nucleotide databases Protein databases
B7H4*01 AY322147 Tr:Q7TSP5 283 aa 1
B7H4*02 AK143276 283 aa 1
B7H4*03 BC032925 Tr:Q8K091 283 aa 1
NM_178594 NP_848709 283 aa 1
IMGT notes:
  1. (1) In EX5 g20>a, c36>t, c41>g, c47>t, c79>t; A27>V and g92>a.
  2. (2) In EX2 [D1], a322>t, T108>S and a336>g, positions according to IMGT unique numbering for V-DOMIAN and V-LIKE-DOMAIN. In EX3 [D2] c135>t and t237>c, positions according to IMGT unique numbering for C-DOMIAN and C-LIKE-DOMAIN. In EX5 c33>t, c38>g, c44>t, t64>c; F22>S, c79>t; A27>V and g92>a.
IMGT references:
  1. [1] Prasad D.V. et al. Immunity 18, 863-873 (2003). PMID:12818166

Genomic sequence

Coding region sequence

The coding region (CODING-REGION) sequence starts from INIT-CODON (or its encoded amino acid) to STOP-CODON (not included).
The nucleotide sequence is extracted from cDNA (c) sequences and/or is built by artificial exon joining from genomic DNA (g) sequences. The amino acid sequence is the translation of the nucleotide sequence.

B7H4*01: AY322147(c)

Nucleotide sequence

1        atggcttcct tggggcagat catcttttgg agtattatta acatcatcat catcctggct

61       ggggccatcg cactcatcat tggctttggc atttcaggca agcacttcat cacggtcacg

121      accttcacct cagctggaaa cattggagag gacgggaccc tgagctgcac ttttgaacct

181      gacatcaaac tcaacggcat cgtcatccag tggctgaaag aaggcatcaa aggtttggtc

241      cacgagttca aagaaggcaa agacgacctc tcacagcagc atgagatgtt cagaggccgc

301      acagcagtgt ttgctgatca ggtggtagtt ggcaatgctt ccctgagact gaaaaacgtg

361      cagctcacgg atgctggcac ctacacatgt tacatccgca cctcaaaagg caaagggaat

421      gcaaaccttg agtataagac cggagccttc agtatgccag agataaatgt ggactataat

481      gccagttcag agagtttacg ctgcgaggct cctcggtggt tcccccagcc cacagtggcc

541      tgggcatctc aagtcgacca aggagccaat ttctcagaag tctccaacac cagctttgag

601      ttgaactctg agaatgtgac catgaaggtc gtatctgtgc tctacaatgt cacaatcaac

661      aacacatact cctgtatgat tgaaaacgac attgccaaag ccaccgggga catcaaagtg

721      acagattcag aggtcaaaag gcggagtcag ctgcagctgc tcaactccgg gccttccccg

781      tgtgtttttt cttctgcctt tgcggctggc tgggcgctcc tatctctctc ctgttgcctg

841      atgctaagat ga
Nucleotide sequence in FASTA format (without gaps) B7H4*01

Amino acid sequence

1        MASLGQIIFW SIINIIIILA GAIALIIGFG ISGKHFITVT TFTSAGNIGE DGTLSCTFEP

61       DIKLNGIVIQ WLKEGIKGLV HEFKEGKDDL SQQHEMFRGR TAVFADQVVV GNASLRLKNV

121      QLTDAGTYTC YIRTSKGKGN ANLEYKTGAF SMPEINVDYN ASSESLRCEA PRWFPQPTVA

181      WASQVDQGAN FSEVSNTSFE LNSENVTMKV VSVLYNVTIN NTYSCMIEND IAKATGDIKV

241      TDSEVKRRSQ LQLLNSGPSP CVFSSAFAAG WALLSLSCCL MLR*
Amino acid sequence in FASTA format (without gap) B7H4*01

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