Other B7 Family entries

IMGT RPI entry from gene to protein for Mus musculus B7A1

Citing IMGT RPI entry for B7A1

Duprat, E. et al. IMGT standardization for alleles and mutations of the V-LIKE-DOMAINs and C-LIKE-DOMAINs of the immunoglobulin superfamily, Recent Research Developments in Human Genetics, 2, 111-136 (2004) pdf with permission from Research Signpost

IMGT gene name and definition

Chromosomal localization

Gene exon/intron organization

B7A1 Gene exon/intron organization

Legend:

Number of alleles: 3

IMGT reference alleles

Allele names Gene functionality Strains IMGT reference sequences
Exons Accession numbers Molecule type
B7A1*01 F EX1 L12585 [1] gDNA splicing A
EX2 L12586
EX3 L12587
EX4 L12588
EX5 L12589
B7A1*02 F A/J EX1-5 AF065893 cDNA splicing B (2)
B7A1*03 F C57BL/6CrSlc EX1-2, EX4-5 D16220 [3] cDNA splicing C (3)

IMGT reference sequences (in FASTA format) for the allele(s): B7A1*01 to B7A1*03

Other sequences from the literature

Allele names Gene functionality Strains IMGT reference sequences
Exons Accession numbers Molecule type
B7A1*01 F NOD EX1-EX5 AK154329[2] cDNA splicing B
C57BL/6J EX1-EX5 AF065894
B10.S/J EX1-EX5 AF065895
SJL/J EX1-EX5 AF065896
EX1-EX5 AJ278965
EX1-EX5 AY278186
EX1-EX5 X60958
EX1-EX5 NM_009855

Corresponding protein database accession numbers

Allele names Accession numbers Number of amino acids Protein isoform
Nucleotide databases Protein databases
B7A1*01 L12585 Q00609 309 aa 1
L12586 309 aa 1
L12587 309 aa 1
L12588 309 aa 1
L12589 309 aa 1
NM_005191 NP_005182 306 aa 2
B7A1*02 AF065893 Tr:Q9R1Z9 306 aa 2
B7A1*03 D16220 212 aa 3
IMGT notes:
  1. (1) Splicing B (306 aa). EX5 utilize the alternate splice site present 3 codons after the usual 5' splice site and the new amino acid G4>R is encoded by the alternative splicing. In EX3 [D2] a50>g, D17>G numbering according to unique numbering for C-LIKE-DOMAIN.
  2. (2) Splicing B (307 aa). EX5 utilize the alternate splice site present 3 codons after the usual 5' splice site and the new amino acid G4>R is encoded by the alternative splicing. In EX5 an insertion of a codon (aga) at position (49^>ins^aga, 7^>ins^R).
  3. (3) No EX3.
IMGT references:
  1. [1] Selvakumar.A, et al. Immunogenetics 36, 175-181 (1992). PMID:7686531
  2. [2] Carninci.P and Hayashizaki.Y., Meth. Enzymol. 303, 19-44 (1999). PMID:10349636
  3. [3] Inobe. M, et al. Biochem. Biophys. Res. Commun. 200, 443-449 (1994). PMID:7513163

Genomic sequence

Coding region sequence

The coding region (CODING-REGION) sequence starts from INIT-CODON (or its encoded amino acid) to STOP-CODON (not included).
The nucleotide sequence is extracted from cDNA (c) sequences and/or is built by artificial exon joining from genomic DNA (g) sequences. The amino acid sequence is the translation of the nucleotide sequence.

B7A1*01: L12585(g) L12586(g) L12587(g) L12588(g) L12589(g)

Nucleotide sequence

1        atggcttgca attgtcagtt gatgcaggat acaccactcc tcaagtttcc atgtccaagg

61       ctcattcttc tctttgtgct gctgattcgt ctttcacaag tgtcttcaga tgttgatgaa

121      caactgtcca agtcagtgaa agataaggta ttgctgcctt gccgttacaa ctctcctcat

181      gaagatgagt ctgaagaccg aatctactgg caaaaacatg acaaagtggt gctgtctgtc

241      attgctggga aactaaaagt gtggcccgag tataagaacc ggactttata tgacaacact

301      acctactctc ttatcatcct gggcctggtc ctttcagacc ggggcacata cagctgtgtc

361      gttcaaaaga aggaaagagg aacgtatgaa gttaaacact tggctttagt aaagttgtcc

421      atcaaagctg acttctctac ccccaacata actgagtctg gaaacccatc tgcagacact

481      aaaaggatta cctgctttgc ttccgggggt ttcccaaagc ctcgcttctc ttggttggaa

541      aatggaagag aattacctgg catcaatacg acaatttccc aggatcctga atctgaattg

601      tacaccatta gtagccaact agatttcaat acgactcgca accacaccat taagtgtctc

661      attaaatatg gagatgctca cgtgtcagag gacttcacct gggaaaaacc cccagaagac

721      cctcctgata gcaagaacac acttgtgctc tttggggcag gattcggcgc agtaataaca

781      gtcgtcgtca tcgttgtcat catcaaatgc ttctgtaagc acaatcttca aggaagctgt

841      ttcagaagaa atgaggcaag cagagaaaca aacaacagcc ttaccttcgg gcctgaagaa

901      gcattagctg aacagaccgt cttcctttag
Nucleotide sequence in FASTA format (without gaps) B7A1*01

Amino acid sequence

1        MACNCQLMQD TPLLKFPCPR LILLFVLLIR LSQVSSDVDE QLSKSVKDKV LLPCRYNSPH

61       EDESEDRIYW QKHDKVVLSV IAGKLKVWPE YKNRTLYDNT TYSLIILGLV LSDRGTYSCV

121      VQKKERGTYE VKHLALVKLS IKADFSTPNI TESGNPSADT KRITCFASGG FPKPRFSWLE

181      NGRELPGINT TISQDPESEL YTISSQLDFN TTRNHTIKCL IKYGDAHVSE DFTWEKPPED

241      PPDSKNTLVL FGAGFGAVIT VVVIVVIIKC FCKHNLQGSC FRRNEASRET NNSLTFGPEE

301      ALAEQTVFL*
Amino acid sequence in FASTA format (without gap) B7A1*01

Legend: