IMGT Repertoire (RPI)

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Other B7 Family entries

Homo sapiens: B7A1, B7A2, B7H1, B7DC, B7H2, B7H3, B7H4
Mus musculus: B7A1, B7A2, B7H1, B7H2, B7H3, B7H4

IMGT RPI entry from gene to protein for Mus musculus B7DC

Citing IMGT RPI entry for B7DC

Duprat, E. et al. IMGT standardization for alleles and mutations of the V-LIKE-DOMAINs and C-LIKE-DOMAINs of the immunoglobulin superfamily, Recent Research Developments in Human Genetics, 2, 111-136 (2004)

with permission from Research Signpost

IMGT gene name and definition

IMGT gene name: Mus musculus B7DC
IMGT gene definition: programmed cell death 1 ligand 2

Chromosomal localization

Chromosome: 19
Chromosomal localization: 19 C2-C3

Gene exon/intron organization

Legend:

Length of the exons and introns are in base pairs.
Colors are according to IMGT Color menu for regions and domains

Number of alleles: 1

IMGT reference alleles

Allele names	Gene functionality	Strain	IMGT reference sequences
Allele names	Gene functionality	Strain	Exons	Accession numbers	Molecule type
B7DC*01	F	BALB/c	EX1-4	AF142780[1]	cDNA

IMGT reference sequences (in FASTA format) for the allele(s): B7DC*01

Nucleotide sequence in FASTA format with gaps according to the IMGT unique numbering
Amino acid sequence in FASTA format with gaps according to the IMGT unique numbering
Nucleotide sequence in FASTA format without gaps
Amino acid sequence in FASTA format without gaps

Other sequences from the literature

Allele names	Gene functionality	Strain	Clones	IMGT reference sequences
Allele names	Gene functionality	Strain	Clones	Exons	Accession numbers	Molecule type
B7DC*01	F	C57BL/6j	F730015O22	EX1-4	AK089369	cDNA
		C57BL/6j	C230055L10	EX1-4	AK141111	cDNA
		NOD	F630115H21	EX1-4	AK155002	cDNA
			MGC:124039	EX1-4	BC104138	cDNA
			MGC:124040	EX1-4	BC104139	cDNA
				EX1-4	NM_021396	cDNA

Corresponding protein database accession numbers

Allele names	Accession numbers		Number of amino acids	Protein isoform
Allele names	Nucleotide databases	Protein databases	Number of amino acids	Protein isoform
B7DC*01	AL162253	Q9WUL5	247 aa	1
B7DC*01	NM_021396	NP_067371	247 aa	1

IMGT references:

[1] Tseng S.Y, et al. J. Exp. Med. 193, 839-846 (2001). PMID:11283156

Genomic sequence

Coding region sequence

The coding region (CODING-REGION) sequence starts from INIT-CODON (or its encoded amino acid) to STOP-CODON (not included).
The nucleotide sequence is extracted from cDNA (c) sequences and/or is built by artificial exon joining from genomic DNA (g) sequences. The amino acid sequence is the translation of the nucleotide sequence.

B7DC*01: AF142780(c)

Nucleotide sequence

1        atgctgctcc tgctgccgat actgaacctg agcttacaac ttcatcctgt agcagcttta

61       ttcaccgtga cagcccctaa agaagtgtac accgtagacg tcggcagcag tgtgagcctg

121      gagtgcgatt ttgaccgcag agaatgcact gaactggaag ggataagagc cagtttgcag

181      aaggtagaaa atgatacgtc tctgcaaagt gaaagagcca ccctgctgga ggagcagctg

241      cccctgggaa aggctttgtt ccacatccct agtgtccaag tgagagattc cgggcagtac

301      cgttgcctgg tcatctgcgg ggccgcctgg gactacaagt acctgacggt gaaagtcaaa

361      gcttcttaca tgaggataga cactaggatc ctggaggttc caggtacagg ggaggtgcag

421      cttacctgcc aggctagagg ttatccccta gcagaagtgt cctggcaaaa tgtcagtgtt

481      cctgccaaca ccagccacat caggaccccc gaaggcctct accaggtcac cagtgttctg

541      cgcctcaagc ctcagcctag cagaaacttc agctgcatgt tctggaatgc tcacatgaag

601      gagctgactt cagccatcat tgaccctctg agtcggatgg aacccaaagt ccccagaacg

661      tggccacttc atgttttcat cccggcctgc accatcgctt tgatcttcct ggccatagtg

721      ataatccaga gaaagaggat ctag

Nucleotide sequence in FASTA format (without gaps) B7DC*01

Amino acid sequence

1        MLLLLPILNL SLQLHPVAAL FTVTAPKEVY TVDVGSSVSL ECDFDRRECT ELEGIRASLQ

61       KVENDTSLQS ERATLLEEQL PLGKALFHIP SVQVRDSGQY RCLVICGAAW DYKYLTVKVK

121      ASYMRIDTRI LEVPGTGEVQ LTCQARGYPL AEVSWQNVSV PANTSHIRTP EGLYQVTSVL

181      RLKPQPSRNF SCMFWNAHMK ELTSAIIDPL SRMEPKVPRT WPLHVFIPAC TIALIFLAIV

241      IIQRKRI*

Amino acid sequence in FASTA format (without gap) B7DC*01

Legend:

Colors are according to IMGT Color menu for regions and domains
Nucleotide and amino acid letters (in bold) in purple, green or blue are according to IMGT Color menu for splicing types.

IMGT links

IMGT Repertoire

Chromosomal localization:
Alignment of alleles:
Protein displays:
IMGT Collier de perles: V-LIKE-DOMAIN, C-LIKE-DOMAIN

External links

Nomenclature

HGNC:

Genome databases

Entrez Gene: 58205
MGI: 1930125
GENATLAS:
GeneCards:
GDB:
OMIM:

Sequence database

EMBL: AF142780, AK089369, AK141111, AK155002, BC104138, BC104139
GenBank: AF142780, AK089369, AK141111, AK155002, BC104138, BC104139
DDBJ: AF142780, AK089369, AK141111, AK155002, BC104138, BC104139
Swiss-Prot:
TrEMBL: Q3U304, Q7TQB5, Q9WUL5
NCBI: NM_021396, NP_067371

Structure database

PDB: