IMGT Repertoire (RPI)

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Other CD3 entries

Homo sapiens: CD3D, CD3E, CD3G
Mus musculus: CD3D, CD3G

IMGT RPI entry from gene to protein for Mus musculus CD3E

Citing IMGT RPI entry for CD3E

Duprat, E. et al. IMGT standardization for alleles and mutations of the V-LIKE-DOMAINs and C-LIKE-DOMAINs of the immunoglobulin superfamily, Recent Research Developments in Human Genetics, 2, 111-136 (2004)

with permission from Research Signpost

IMGT gene name and definition

IMGT gene name: Mus musculus CD3E
IMGT gene definition: CD3E antigen, epsilon polypeptide (TiT3 complex)

Chromosomal localization

Chromosome: 9
Chromosomal localization: 9 26.0cM

Gene exon/intron organization

Legend:

Length of the exons and introns are in base pairs.
Colors are according to IMGT Color menu for regions and domains

Number of alleles: 1

IMGT reference alleles

Allele names	Gene functionality	IMGT reference sequences
Allele names	Gene functionality	Exons	Accession numbers	Molecule type
CD3E*01	F	EX1	M23370	gDNA
		EX2	M23371	gDNA
		EX3	M23372	gDNA
		EX4	M23373	gDNA
		EX5	M23374	gDNA
		EX6	M23375	gDNA
		EX7	M23376	gDNA

IMGT reference sequences (in FASTA format) for the allele(s): CD3E*01

Nucleotide sequence in FASTA format with gaps according to the IMGT unique numbering
Amino acid sequence in FASTA format with gaps according to the IMGT unique numbering
Nucleotide sequence in FASTA format without gaps
Amino acid sequence in FASTA format without gaps

Other sequences from the literature

Allele names	Gene functionality	IMGT reference sequences
Allele names	Gene functionality	Exons	Accession numbers	Molecule type
CD3E*01	F	EX1-7	J02990	cDNA
CD3E*01	F	EX1-7	NM_007648	cDNA

Corresponding protein database accession numbers

CD3E	Accession numbers		Number of amino acids	Protein isoform
CD3E	Nucleotide databases	Protein databases	Number of amino acids	Protein isoform
CD3E*01	M23370	P22646	189 aa	1
	M23371		189 aa	1
	M23372		189 aa	1
	M23373		189 aa	1
	M23374		189 aa	1
	M23375		189 aa	1
	M23376		189 aa	1
	NM_007648	NP_031674	189 aa	1

IMGT references:

[1] Clevers H. et all, Proc. Natl. Acad. Sci. U.S.A. 85, 8623-8627 (1988). PMID:2973066

Genomic sequence

Coding region sequence

The coding region (CODING-REGION) sequence starts from INIT-CODON (or its encoded amino acid) to STOP-CODON (not included).
The nucleotide sequence is extracted from cDNA (c) sequences and/or is built by artificial exon joining from genomic DNA (g) sequences. The amino acid sequence is the translation of the nucleotide sequence.

CD3E*01: M23370(g) M23371(g) M23372(g) M23373(g) M23374(g) M23375(g) M23376(g)

Nucleotide sequence

1        atgcggtgga acactttctg gggcatcctg tgcctcagcc tcctagctgt tggcacttgc

61       caggacgatg ccgagaacat tgaatacaaa gtctccatct caggaaccag tgtagagttg

121      acgtgccctc tagacagtga cgagaactta aaatgggaaa aaaatggcca agagctgcct

181      cagaagcatg ataagcacct ggtgctccag gatttctcgg aagtcgagga cagtggctac

241      tacgtctgct acacaccagc ctcaaataaa aacacgtact tgtacctgaa agctcgagtg

301      tgtgagtact gtgtggaggt ggacctgaca gcagtagcca taatcatcat tgttgacatc

361      tgtatcactc tgggcttgct gatggtcatt tattactgga gcaagaatag gaaggccaag

421      gccaagcctg tgacccgagg aaccggtgct ggtagcaggc ccagagggca aaacaaggag

481      cggccaccac ctgttcccaa cccagactat gagcccatcc gcaaaggcca gcgggacctg

541      tattctggcc tgaatcagag agcagtctga

Nucleotide sequence in FASTA format (without gaps) CD3E*01

Amino acid sequence

1        MRWNTFWGIL CLSLLAVGTC QDDAENIEYK VSISGTSVEL TCPLDSDENL KWEKNGQELP

61       QKHDKHLVLQ DFSEVEDSGY YVCYTPASNK NTYLYLKARV CEYCVEVDLT AVAIIIIVDI

121      CITLGLLMVI YYWSKNRKAK AKPVTRGTGA GSRPRGQNKE RPPPVPNPDY EPIRKGQRDL

181      YSGLNQRAV*

Amino acid sequence in FASTA format (without gap) CD3E*01

Legend:

Colors are according to IMGT Color menu for regions and domains
Nucleotide and amino acid letters (in bold) in purple, green or blue are according to IMGT Color menu for splicing types.

IMGT links

IMGT Repertoire

Chromosomal localization:
Alignment of alleles:
Protein displays:
IMGT Collier de perles: C-LIKE-DOMAIN

IMGT databases

IMGT/3Dstructure-DB: Ijbj, 1xmw

External links

Nomenclature

HGNC:

Genome database

Entrez Gene: 12501
MGI: 88332
GENATLAS:
GeneCards:
GDB:
OMIM:

Sequence database

EMBL: M23370, M23371, M23372, M23373, M23374, M23375, M23376, J02990
GenBank: M23370, M23371, M23372, M23373, M23374, M23375, M23376, J02990
DDBJ: M23370, M23371, M23372, M23373, M23374, M23375, M23376, J02990
Swiss-Prot: P22646
TrEMBL:
NCBI: NM_007648, NP_031674

Structure database

PDB: 1JBJ, 1XMW