IMGT Repertoire (RPI)

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Other CD2 Family entries

Homo sapiens: CD2, CD58, CD48, CD84, CD244, SLAMF1, SLAMF6, Ly9
Mus musculus: CD2, CD48, CD84, CD244, SLAMF1, Ly9

IMGT RPI entry from gene to protein for Mus musculus SLAMF6

Citing IMGT RPI entry for SLAMF6

Duprat, E. et al. IMGT standardization for alleles and mutations of the V-LIKE-DOMAINs and C-LIKE-DOMAINs of the immunoglobulin superfamily, Recent Research Developments in Human Genetics, 2, 111-136 (2004)

with permission from Research Signpost

IMGT gene name and definition

IMGT gene name: Mus musculus SLAMF6
IMGT gene definition: SLAM Family Member 6

Chromosomal localization

Chromosome: 1
Chromosomal localization: 1 H3|1 89.5 cM

Gene exon/intron organization

Legend:

Length of the exons and introns are in base pairs.
Colors are according to IMGT Color menu for regions and domains

Number of alleles: 3

IMGT reference alleles

Allele names	Gene functionality	Strains	IMGT reference sequences
Allele names	Gene functionality	Strains	Exons	Accession numbers	Molecule type
SLAMF6*01	F	C57BL/6J	EX1-8	AF248636 [1]	cDNA
SLAMF6*02	F	NZB/BINJ	EX1-8	BC030031	cDNA (1)
SLAMF6*03	F	C57BL/6J	EX1-8	AB196809	cDNA (2)

IMGT reference sequences (in FASTA format) for the allele(s): SLAMF6*01 to SLAMF6*03

Nucleotide sequence in FASTA format with gaps according to the IMGT unique numbering
Amino acid sequence in FASTA format with gaps according to the IMGT unique numbering
Nucleotide sequence in FASTA format without gaps
Amino acid sequence in FASTA format without gaps

Other sequences from the literature

Allele names	Gene functionality	Strains	IMGT reference sequences
Allele names	Gene functionality	Strains	Exons	Accession numbers	Molecule type
SLAMF6*01	F	BXSB/MpJ	EX1-8	AB196811	cDNA
		NZW/LacJ	EX1-8	AB196810
		MRL/MpJ	EX1-7,9	AB196808
		C57BL/6	EX1-7,9	AF248635	cDNA splicing B (3)
		C57BL/6	EX1-7,9	AB196836	cDNA splicing B
			EX1-7,9	NM_030710	cDNA splicing B

Corresponding protein database accession numbers

Allele names	Accession numbers		Number of amino acids	Protein isoform
Allele names	Nucleotide databases	Protein databases	Number of amino acids	Protein isoform
SLAMF6*01	AF248636	Tr:Q9ET39	351aa	1
SLAMF6*02	BC030031	Tr:Q9ET39	351aa	1
SLAMF6*03	AB196809	Tr:Q18PJ2	351aa	1
SLAMF6*01	AB196836	Tr:Q18PG5	331aa	2
SLAMF6*01	NM_030710	NP_109635	331aa	2

IMGT notes:

(1) In EX3 [D2] 6t>c, numbering according to IMGT unique numbering for C-LIKE-DOMAIN and in EX4 65a>t.
(2) In EX2 [D1] 320c>t, 107T>I, numbering according to IMGT unique numbering for V-LIKE-DOMAIN and in EX3 [D2] 6t>c and 364g>a, numbering according to IMGT unique numbering for C-LIKE-DOMAIN.
(3) Splicing B (331 aa). No EX8 and utilize a novel exon (EX9) of 15 bases.

IMGT references:

[1] Peck S.R. and Ruley H.E, Immunogenetics 52, 63-72 (2000). PMID:11132158

Genomic sequence

Coding region sequence

The coding region (CODING-REGION) sequence starts from INIT-CODON (or its encoded amino acid) to STOP-CODON (not included).
The nucleotide sequence is extracted from cDNA (c) sequences and/or is built by artificial exon joining from genomic DNA (g) sequences. The amino acid sequence is the translation of the nucleotide sequence.

SLAMF6*01: AF248636(c)

Nucleotide sequence

1        atggctgtct caagggctcc agcacccgac tccgcctgtc agaggatggt ctggctcttt

61       ccacttgtct tctgcctcgg ctcagggagt gaagtttcac agagcagctc agacccccag

121      ctaatgaatg gcgttctagg agagtctgca gttcttcctc taaagcttcc tgcagggaag

181      atagccaata tcatcatctg gaattatgaa tgggaagcgt cacaagtcac tgccctcgtt

241      atcaacctaa gtaatcctga aagtccacaa atcatgaaca ctgatgtaaa gaagagactg

301      aacatcaccc agtcctactc cctgcaaatc agcaacctta ccatggcaga cacaggatca

361      tacactgcgc agataaccac aaaggactct gaagtgatca ccttcaaata tattctgagg

421      gtctttgaac gattgggtaa cttagaaact accaactata ctctcctgct agagaatggg

481      acctgccaga tacacctggc ctgtgttttg aagaatcaaa gtcaaactgt ctcagttgag

541      tggcaagcca caggaaacat ctctttagga ggaccaaatg tcactatctt ttgggacccg

601      aggaattctg gtgaccagac ttacgtctgc agagccaaga atgctgtcag caatttgtca

661      gtctctgttt cgacccagag tctctgcaaa ggggttctaa ctaatccacc ctggaatgca

721      gtatggttta tgactacaat ttcaataatc agtgcagtca tactcatctt tgtgtgctgg

781      agcatacatg tttggaagag aagaggttct cttcctttga ctagccaaca tccagagtcc

841      tcccagagca cagatggccc aggctctcca gggaacactg tgtatgcaca agtcactcgt

901      ccaatgcagg aaatgaaaat cccaaaacct atcaaaaatg actccatgac aatttactcc

961      atagttaatc attccagaga ggaaacagtg gctttaaccg gctataacca acccattacc

1021     ctgaaggtta acactttaat caactataac tcctga

Nucleotide sequence in FASTA format (without gaps) SLAMF6*01

Amino acid sequence

1        MAVSRAPAPD SACQRMVWLF PLVFCLGSGS EVSQSSSDPQ LMNGVLGESA VLPLKLPAGK

61       IANIIIWNYE WEASQVTALV INLSNPESPQ IMNTDVKKRL NITQSYSLQI SNLTMADTGS

121      YTAQITTKDS EVITFKYILR VFERLGNLET TNYTLLLENG TCQIHLACVL KNQSQTVSVE

181      WQATGNISLG GPNVTIFWDP RNSGDQTYVC RAKNAVSNLS VSVSTQSLCK GVLTNPPWNA

241      VWFMTTISII SAVILIFVCW SIHVWKRRGS LPLTSQHPES SQSTDGPGSP GNTVYAQVTR

301      PMQEMKIPKP IKNDSMTIYS IVNHSREETV ALTGYNQPIT LKVNTLINYN S*

Amino acid sequence in FASTA format (without gap) SLAMF6*01

Legend:

Colors are according to IMGT Color menu for regions and domains
Nucleotide and amino acid letters (in bold) in purple, green or blue are according to IMGT Color menu for splicing types.

IMGT links

IMGT RepertoireChromosomal localization

Alignment of alleles:
Protein displays:
IMGT Collier de perles: V-LIKE-DOMAIN, C-LIKE-DOMAIN

External links

Nomenclature

HGNC:

Genome databases

Entrez Gene: 30925
MGI: 1353620
GENATLAS:
GeneCards:
GDB:
OMIM:

Seauence databases

EMBL: AF248636, BC030031, AB196809, AB196811, AB196810, AB196808, AF248635, AB196836
GenBank: AF248636, BC030031, AB196809, AB196811, AB196810, AB196808, AF248635, AB196836
DDBJ: AF248636, BC030031, AB196809, AB196811, AB196810, AB196808, AF248635, AB196836
Swiss-Prot:
TrEMBL: Q9ET39, Q9ET39, Q18PJ2, Q18PG5
NCBI: NM_030710, NP_109635

Struture database

PDB: