Other Ly9 entries

IMGT RPI entry from gene to protein for Homo sapiens Ly9

Citing IMGT RPI entry for Ly9

Duprat, E. et al. IMGT standardization for alleles and mutations of the V-LIKE-DOMAINs and C-LIKE-DOMAINs of the immunoglobulin superfamily, Recent Research Developments in Human Genetics, 2, 111-136 (2004) pdf with permission from Research Signpost

IMGT gene name and definition

Chromosomal localization

Gene exon/intron organization

Ly9 Gene exon/intron organization

Legend:

Number of alleles: 4

IMGT reference alleles

Allele names Gene functionality IMGT reference sequences
Exons Accession numbers Molecule type
Ly9*01 F EX1-10 AL121985 gDNA
Ly9*02 F EX1-10 AF244129[1] cDNA (1)
Ly9*03 F EX1-10 L42621[2] cDNA (2) partial
Ly9*04 F EX3-4,6-10 BC121049 cDNA (3) splicing B

IMGT reference sequences (in FASTA format) for the allele(s): Ly9*01 to Ly9*04

Other sequences from the literature

Allele names Gene functionality IMGT reference sequences
Exons Accession numbers Molecule type
Ly9*01 F EX1-2, EX11 BC064485 cDNA (4) splicing C
NM_001033667 cDNA splicing C
Ly9*02 F EX1-10 AY007142 cDNA
NM_002348 cDNA
EX3-4,6-10 BC027920 cDNA splicing B

Corresponding protein database accession numbers

Allele Name Accession numbers Number of amino acids Protein isoform
Nucleotide databases Protein databases
Ly9*01 AL121985 Q9HBG7 655 aa 1
NM_001033667 NP_001028839 193 aa 3
Ly9*02 AF244129 Tr: Q0VAI0 654 aa 1
NM_002348 NP_002339 654 aa 1
Ly9*03 L42621 610 aa 1
Ly9*04 BC121049 405 aa 2
IMGT notes:
  1. (1) In EX3[D2], codon 46-48(cct)>#del; S16>#del, numbering according to IMGT unique numbering for C-DOMAIN and C-LIKE-DOMAIN. In EX8 a189>g; a307>g, M103>V. In EX9 the 3' splice site is shifted to one codon upstream.
  2. (2) Partial EX1. In EX8 a189>g; a307>g, M103>V. In EX9 the 3' splice site is shifted to one codon upstream.
  3. (3) Uses alternative start codon 'atg' in EX3. In EX3 c151>g, R51>G. No EX5. In EX9 the 3' splice site is shifted to one codon upstream.
  4. (4) Splicing C (193 aa). No EX3-10. EX2 do not have the splice site and extends 41 codons beyond the normal splice site.
IMGT references:
  1. [1] Tovar V. et al., Immunogenetics 51, 788-793 (2000). PMID:10970093
  2. [2] Sandrin M.S. et al., Immunogenetics 43, 13-19 (1996). PMID:8537117

Genomic sequence

Coding region sequence

The coding region (CODING-REGION) sequence starts from INIT-CODON (or its encoded amino acid) to STOP-CODON (not included).
The nucleotide sequence is extracted from cDNA (c) sequences and/or is built by artificial exon joining from genomic DNA (g) sequences. The amino acid sequence is the translation of the nucleotide sequence.

Ly9*01: AL121985(g)

Nucleotide sequence

1        atggtggcac caaagagtca cacagatgac tgggctcctg ggcctttctc cagtaagcca

61       cagaggagtc agctgcaaat attctcttct gttctacaga cctctctcct cttcctgctc

121      atgggactaa gagcctctgg aaaggactca gccccaacag tggtgtcagg gatcctaggg

181      ggttccgtga ctctccccct aaacatctca gtagacacag agattgagaa cgtcatctgg

241      attggtccca aaaatgctct tgctttcgca cgtcccaaag aaaatgtaac cattatggtc

301      aaaagctacc tgggccgact agacatcacc aagtggagtt actccctgtg catcagcaat

361      ctgactctga atgatgcagg atcctacaaa gcccagataa accaaaggaa ttttgaagtc

421      accactgagg aggaattcac cctgttcgtc tatgagcagc tgcaggagcc ccaagtcacc

481      atgaagtctg tgaaggtgtc tgagaacttc tcctgtaaca tcactctaat gtgctccgtg

541      aagggggcag agaaaagtgt tctgtacagc tggaccccaa gggaacccca tgcttctgag

601      tccaatggag gctccattct taccgtctcc cgaacaccat gtgacccaga cctgccatac

661      atctgcacag cccagaaccc cgtcagccag agaagctccc tccctgtcca tgttgggcag

721      ttctgtacag atccaggagc ctccagagga ggaacaacgg gggagactgt ggtaggggtc

781      ctgggagagc cagtcaccct gccacttgca ctcccagcct gccgggacac agagaaggtt

841      gtctggttgt ttaacacatc catcattagc aaagagaggg aagaagcagc aacggcagat

901      ccactcatta aatccaggga tccttacaag aacagggtgt gggtctccag ccaggactgc

961      tccctgaaga tcagccagct gaagatagag gacgccggcc cctaccatgc ctacgtgtgc

1021     tcagaggcct ccagcgtcac cagcatgaca catgtcaccc tgctcatcta ccgcaggctg

1081     aggaagccca aaatcacgtg gagcctcagg cacagtgagg atggcatctg caggatcagc

1141     ctgacctgct ccgtggagga cgggggaaac actgtcatgt acacatggac cccgctgcag

1201     aaggaagctg ttgtgtccca aggggaatca cacctcaatg tctcatggag aagcagtgaa

1261     aatcacccca acctcacatg cacagccagc aaccctgtca gcaggagttc ccaccagttt

1321     ctttctgaga acatctgttc aggacctgag agaaacacaa agctttggat tgggttgttc

1381     ctgatggttt gccttctgtg cgttgggatc ttcagctggt gcatttggaa gcgaaaagga

1441     cggtgttcag tcccagcctt ctgttccagc caagctgagg ccccagcgga tacaccagaa

1501     cccacagctg gccacacgct atactctgtg ctctcccaag gatatgagaa gctggacact

1561     cccctcaggc ctgccaggca acagcctaca cccacctcag acagcagctc tgacagcaac

1621     ctcacaactg aggaggatga ggacaggcct gaggtgcaca agcccatcag tggaagatat

1681     gaggtatttg accaggtcac tcaggagggc gctggacatg acccagcccc tgagggccaa

1741     gcagactatg atcccgtcac tccatatgtc acggaagttg agtctgtggt tggagagaac

1801     accatgtatg cacaagtgtt caacttacag ggaaagaccc cagtttctca gaaggaagag

1861     agctcagcca caatctactg ctccatacgg aaacctcagg tggtggtgcc accaccacaa

1921     cagaatgatc ttgagattcc tgaaagtcct acctatgaaa atttcacctg a
Nucleotide sequence in FASTA format (without gaps) Ly9*01

Amino acid sequence

1        MVAPKSHTDD WAPGPFSSKP QRSQLQIFSS VLQTSLLFLL MGLRASGKDS APTVVSGILG

61       GSVTLPLNIS VDTEIENVIW IGPKNALAFA RPKENVTIMV KSYLGRLDIT KWSYSLCISN

121      LTLNDAGSYK AQINQRNFEV TTEEEFTLFV YEQLQEPQVT MKSVKVSENF SCNITLMCSV

181      KGAEKSVLYS WTPREPHASE SNGGSILTVS RTPCDPDLPY ICTAQNPVSQ RSSLPVHVGQ

241      FCTDPGASRG GTTGETVVGV LGEPVTLPLA LPACRDTEKV VWLFNTSIIS KEREEAATAD

301      PLIKSRDPYK NRVWVSSQDC SLKISQLKIE DAGPYHAYVC SEASSVTSMT HVTLLIYRRL

361      RKPKITWSLR HSEDGICRIS LTCSVEDGGN TVMYTWTPLQ KEAVVSQGES HLNVSWRSSE

421      NHPNLTCTAS NPVSRSSHQF LSENICSGPE RNTKLWIGLF LMVCLLCVGI FSWCIWKRKG

481      RCSVPAFCSS QAEAPADTPE PTAGHTLYSV LSQGYEKLDT PLRPARQQPT PTSDSSSDSN

541      LTTEEDEDRP EVHKPISGRY EVFDQVTQEG AGHDPAPEGQ ADYDPVTPYV TEVESVVGEN

601      TMYAQVFNLQ GKTPVSQKEE SSATIYCSIR KPQVVVPPPQ QNDLEIPESP TYENFT*
Amino acid sequence in FASTA format (without gap) Ly9*01

Legend: