IMGT Web resources

 Here you are: IMGT Web resources > IMGT Education > Tutorials > Immunoglobulins and B cells

Papain digested immunoglobulin: 2 Fab and 1 Fc

IgG1 proteolytic cleavage by the papain gives two Fab fragments and a Fc fragment.

Fab Fab
 
Fc

VH corresponds to the V-D-J-REGION (in green (V), orange (DJ)) of the heavy chain.
VL corresponds to the V-J-REGION (in green (V) and yellow (J)) of the light chain.

The corresponding PDB (Protein Data Bank) format file is from Mike's immunoglobulin structure function site (http://www.umass.edu/microbio/rasmol/padlan.htm).


Created: 28/06/2001
Last updated: Monday, 20-Jan-2020 21:00:17 CET
Author: Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr
Editors: Elodie Foulquier, Chantal Ginestoux