Proteins with known 3D structures
Overview: Human Immunoglobulins
Overview table  Identification of the genes and alleles involved in the rearrangements and expressed in the variable regions Protein display of the Ig V-D-J and V-J REGIONs

"OVERVIEW" gives information on proteins whose three-dimensional structure has been determined.
"IDENTIFICATION AND COLLIERS DE PERLES" provides
  • the identification of the genes and alleles expressed in the IGH V-DOMAINs (V-D-J-REGIONs) and in the IGK and IGL V-DOMAINs (V-J-REGIONs)
  • the Colliers de Perles of the IGH, IGK and IGL V-DOMAINs.
    "PROTEIN DISPLAY" provides the Protein displays of the IGH, IGK and IGL V-DOMAINs.

    Click here to see: Part 1 - Human immunoglobulin proteins (in alphabetic order)

    Part 2 - Human immunoglobulin proteins (in the PDB code order)
    Reference of this table: Ruiz, M. and Lefranc, M.-P., Immunogenetics, 53, 857-883 (2002) PMID:11862387, LIGM:259

    Updates from 09/05/2001 are available in IMGT/3Dstructure-DB. IMGT/3Dstructure-DB entries (cards) are identified by the PDB code.
    Click on a PDB code to get the corresponding IMGT/3Dstructure-DB card.

    PDB Code
    Protein Name
    Fragment (1) Ligands Experimental Technique Resolution PDB Release Date References
    1a8j
    Mcg
    L2
    Aspartame
    X-ray diffraction
    2.70
    17-jun-98
    25
    1adq
    Rf-An
    Fab
    Autoantigen IgG Fc
    X-ray diffraction
    3.15
    16-sep-98
    21
    1aqk
    B7-15A2
    Fab
     
    X-ray diffraction
    1.84
    04-feb-98
    26
    1ar2
    Rei
    VL
     
    X-ray diffraction
    2.80
    12-nov-97
    24
    1b0w
    Bre
    VL
     
    X-ray diffraction
    1.80
    22-dec-99
    31
    1bjm
    Loc
    L2
     
    X-ray diffraction
    2.20
    07-dec-95
    19
    1bre
    Bre
    VL
     
    X-ray diffraction
    2.00
    15-oct-95
    16
    1bvk
    HULYS11
    Fv
    Lysozyme [hen egg white]
    X-ray diffraction
    2.70
    16-feb-99
    27
    1bvl
    HULYS11
    Fv
     
    X-ray diffraction
    2.87
    16-feb-99
    22
    1bww
    Reiv-T39K
    VL
     
    X-ray diffraction
    1.70
    29-dec-99
    24
    1cd0
    Jto
    (VL)2
     
    X-ray diffraction
    1.90
    06-mar-00
    36
    1cz8
    Fab-12
    Fab
    Vascular endothelial growth factor
    X-ray diffraction
    2.40
    20-mar-00
    33
    1dcl
    Mcg
    L2
     
    X-ray diffraction
    2.30
    15-may-97
    5
    1dee
    IgmRf2A2
    Fab
     
    X-ray diffraction
    2.70
    14-jun-00
    41
    1dfb
    3D6
    Fab
     
    X-ray diffraction
    2.70
    31-oct-93
    10
    1dql
    Mez
    Fv
     
    X-ray diffraction
    2.60
    04-oct-00
    44
    1dl7
    M3C65
    Fv
     
    X-ray diffraction
    2.35
    13-dec-00
    39
    1dx3
    9E
    Fv
     
    theoretical model
     
    15-dec-00
    38
    1e4k
    Undefined
    Fc
    Fc gamma III low affinity receptor (CD16)
    X-ray diffraction
    3.20
    06-aug-00
    45
    1eeq
    M4L/Y(27D)D/T94H Mutant Of Len
    (VL)2
     
    X-ray diffraction
    1.50
    01-feb-01
    51
    1eeu
    M4L/Y(27D)D/Q89D/T94H Mutant Of Len
    (VL)2
     
    X-ray diffraction
    1.60
    03-feb-01
    51
    1efq
    Q38D Mutant Of Len
    VL
     
    X-ray diffraction
    1.60
    09-feb-01
    51
    1ek3
    Rec
    (VL)2
     
    X-ray diffraction
    1.90
    06-mar-01
    51
    1f6a
    Undefined
    Fc
    Fc epsilon RI alpha (high-affinity receptor)
    X-ray diffraction
    3.50
    20-jul-00
    40
    1fc1
    IgG1
    Fc
     
    X-ray diffraction
    2.90
    15-jul-92
    3
    1fc2
    IgG1
    Fc
    Fragment B of protein A [Staphylococcus aureus]
    X-ray diffraction
    2.80
    15-jul-92
    3
    1fh5
    Mak33
    Fab
     
    X-ray diffraction
    2.90
    13-sep-00
    47
    1fp5
    Ige Epsilon-1
    Fc
     
    X-ray diffraction
    2.30
    27-sep-00
    46
    1g84
    IgE Cepsilon2
    CH2
     
    NMR, 15 structures
     
    16-may-01
    48
    1g9n
    17B
    Fab
    HIV-1 gp120 (envelope protein)/CD4
    X-ray diffraction
    2.90
    27-dec-00
    42
    1g9m
    17B
    Fab
    HIV-1 gp120 (envelope protein)/CD4
    X-ray diffraction
    2.20
    27-dec-00
    28
    1gc1
    17B
    Fab
    HIV-1 gp120 (envelope protein)/CD4
    X-ray diffraction
    2.50
    19-aug-98
    28
    1hou
    Undefined
    Fv
     
    theoretical model
     
    23-dec-99
    34
    1iga
    Iga1
    IgA
     
    theoretical model; scattering fitting
     
    15-jun-99
    32
    1igm
    Pot
    Fv
     
    X-ray diffraction
    2.30
    31-oct-93
    9
    1iis
    IgG1
    Fc
    Fc gamma III low affinity receptor
    X-ray diffraction
    3.00
    09-may-01
    49
    1iix
    IgG1
    Fc
    Fc gamma III low affinity receptor
    X-ray diffraction
    3.50
    09-may-01
    49
    1lil
    Cle
    L2
     
    X-ray diffraction
    2.65
    15-may-97
    20
    1lve
    Len
    VL
     
    X-ray diffraction
    1.95
    21-jan-98
    23
    1mcb
    Mcg
    L2
    N-Acetyl-L-Gln-D-Phe-L-His-D-Pro-OH
    X-ray diffraction
    2.70
    31-jan-94
    13
    1mcc
    Mcg
    L2
    N-Acetyl-L-Gln-D-Phe-L-His-D-Pro-NH2
    X-ray diffraction
    2.70
    31-jan-94
    13
    1mcd
    Mcg
    L2
    N-Acetyl-D-Phe-B-Ala-L-His-D-Pro-NH2
    X-ray diffraction
    2.70
    31-jan-94
    12
    1mce
    Mcg
    L2
    N-Acetyl-L-Gln-D-Phe-L-His-D-Pro-B-Ala-OH
    X-ray diffraction
    2.70
    31-jan-94
    13
    1mcf
    Mcg
    L2
    N-Acetyl-L-Gln-D-Phe-L-His-D-Pro-B-Ala-B-Ala-OH
    X-ray diffraction
    2.70
    31-jan-94
    12
    1mch
    Mcg
    L2
    N-Acetyl-L-Gln-D-Phe-L-His-D-Pro-B-Ala-B-Ala-OH
    X-ray diffraction
    2.70
    31-jan-94
    13
    1mci
    Mcg
    L2
    N-Acetyl-D-Phe-L-His-D-Pro-OH
    X-ray diffraction
    2.70
    31-jan-94
    13
    1mcj
    Mcg
    L2
    N-Acetyl-D-Phe-L-His-D-Pro-NH2
    X-ray diffraction
    2.70
    31-jan-94
    13
    1mck
    Mcg
    L2
    N-Acetyl-D-Glu-L-His-D-Pro-NH2
    X-ray diffraction
    2.70
    31-jan-94
    13
    1mcl
    Mcg
    L2
    N-Acetyl-D-His-L-Pro-OH
    X-ray diffraction
    2.70
    31-jan-94
    13
    1mcn
    Mcg
    L2
    N-Acetyl-D-His-L-Pro-NH2
    X-ray diffraction
    2.70
    31-jan-94
    13
    1mco
    Mcg
    Ig with a hinge deletion
     
    X-ray diffraction
    3.20
    31-jan-94
    14
    1mcq
    Mcg
    L2
    N-Acetyl-L-His-D-Pro-NH2
    X-ray diffraction
    2.70
    31-jan-94
    13
    1mcr
    Mcg
    L2
    N-Acetyl-L-His-D-Pro-OH
    X-ray diffraction
    2.70
    31-jan-94
    13
    1mcs
    Mcg
    L2
    N-Acetyl-L-Gln-D-Phe-L-His-D-Pro-OH
    X-ray diffraction
    2.70
    31-jan-94
    13
    1mcw
    Mcg-Weir Hybrid
    L2
     
    X-ray diffraction
    3.50
    15-oct-90
    7
    1obe
    3D6
    Fab
    HIV-1 gp41 synthetic peptide
    theoretical model
     
    15-may-97
    17
    1qac
    Undefined
    (VL)2
     
    X-ray diffraction
    1.80
    23-feb-00
    43
    1qlr
    Kau Cold Agglutinin
    Fab
     
    X-ray diffraction
    2.83
    14-sep-00
    50
    1qp1
    Bre
    (VL)3
     
    X-ray diffraction
    2.06
    28-jun-99
    37
    1rei
    Rei
    (VL)2
     
    X-ray diffraction
    2.00
    17-feb-84
    1
    1vge
    Tr1.9
    Fab
     
    X-ray diffraction, single crystal
    2.00
    10-jun-96
    18
    1wtl
    Wat
    (VL)2
     
    X-ray diffraction
    1.90
    01-nov-94
    15
    2cd0
    Wil
    (VL)2
     
    X-ray diffraction
    1.80
    08-mar-00
    36
    2fb4
    Kol
    Fab
     
    X-ray diffraction
    1.90
    12-jul-89
    6
    2ig2
    Kol
    Fab
     
    X-ray diffraction
    3.00
    12-jul-89
    6
    2loi
    Loi
    (VL)2
     
    theoretical model
     
    29-dec-99
    35
    2lve
    Len
    VL
     
    X-ray diffraction
    2.70
    18-may-99
    29
    2mcg
    Mcg
    L2
     
    X-ray diffraction
    2.00
    15-jul-92
    2
    2rhe
    Rhe
    VL
     
    X-ray diffraction
    1.60
    09-oct-88
    4
    3bjl
    Loc
    L2
     
    X-ray diffraction
    2.30
    07-dec-95
    19
    3lve
    Len (mutant)
    VL
     
    X-ray diffraction
    2.00
    18-may-99
    30
    3mcg
    Mcg
    L2
     
    X-ray diffraction
    2.00
    15-oct-90
    5
    4bjl
    Loc
    L2
     
    X-ray diffraction
    2.40
    07-dec-95
    19
    4lve
    Len (mutant)
    (VL)2
     
    X-ray diffraction
    2.30
    18-may-99
    29
    5lve
    Len
    VL
     
    X-ray diffraction
    2.00
    18-feb-00
    30
    7fab
    Newm (2)
    Fab
     
    X-ray diffraction
    2.00
    31-jan-94
    11
    8fab
    Hil
    Fab
     
    X-ray diffraction
    1.80
    31-oct-93
    8


    IMGT notes:

    (1) Fragment legend :
    VHIg heavy V-DOMAIN.
    VLIg light V-DOMAIN.
    FabFragment antigen-binding. Complete light chain (Ig light V-DOMAIN and C-DOMAIN) disulfide-linked with an Ig heavy V-DOMAIN and CH1 C-DOMAIN.
    FvIg heavy V-DOMAIN (VH) non covalently linked with an Ig light V-DOMAIN (VL).
    FcFragment crystallizable. Two identical disulfide-linked Ig heavy CH2 and CH3 C-DOMAINs.
    (VL)nn Ig light V-DOMAINs non covalently linked.
    L2Dimer of two non covalently linked complete light chains.
    IgAComplete Immunoglobulin A.
    scFvTwo Ig (or by extension T cell receptor) V-DOMAINs covalently linked.
    CH2Ig heavy CH2 C-DOMAIN.

    (2) Click here for "Particularities in protein designations: Human immunoglobulins: New and Newm "


    Created: 26/06/2001
    Last updated: Wednesday, 12-Jun-2024 16:02:20 CEST
    Author: Manuel Ruiz