Citing IMGT dynamic tools: Sanou G., Zeitoun G. et al. IMGT® at scale: FAIR, Dynamic and Automated Tools for Immune Locus Analysis, Nucleic Acids Research. 2025;,gkaf1024. doi: 10.1093/nar/gkaf1024 (Free Article) PMID: 41091930.
Program version: v. 

Add information about removed genes/alleles.
May 15th, 2025.

Add the possibility to obtain a gene table per strain (for mouse now and for other species later) and allotypes/isotypes for human.
September 25th, 2024.

Bibliographical references in alphabetic order, small design changes and addition of "NL" for non-localized gene.
June 14th, 2024.

Addition of 'Score for IMGT allele confirmation' as well as NCBI TPA accession numbers.
September 20th, 2023.

Implementation of the dynamic gene table.

Gene table legend:

"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) rearranged (R), transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene, when the data have been confirmed by several studies.

Functionality is shown in parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.

IMGT allele confirmation: A scoring system is employed to indicate the number of IMGT/LIGM-DB reference sequences and other sequences from the literature in which an IG or TR gene allele has been identified and annotated.

Removed genes/alleles
If a gene/allele existence or name has to be changed, the old name or gene/allele would be deleted and its name won't be reused. They are kept in the gene table for historical reasons.
A single star ()
indicates that an IG or TR gene allele is annotated in the reference sequence only.
Two stars ()
indicate that an IG or TR gene allele is annotated in its reference sequence and in one sequence from the literature.
Three stars ()
indicate that an IG or TR gene allele is annotated in its reference sequence and in at least two sequences from the literature.
In the Excel file, the stars are represented by the plus symbol (+).

Click on:
  • IMGT gene name to get the corresponding IMGT/GENE-DB entry (link).
  • IMGT allele name to see the corresponding Alignments of alleles (link).
  • Accession number to get the corresponding IMGT/LIGM-DB entry (link).
  • MAP: mapped sequences. Click to access GENE-DB «LOCALIZATION IN GENOME ASSEMBLIES» (link).
  • [number] to access the corresponding IMGT reference (popover).
  • (number) to see the corresponding IMGT note (popover).
Options:
  • You can show/hide columns (), download data () or put the table in fullscreen () using buttons.
See also (IMGT Scientific chart):
Select a species and a IMGT group to get the gene table:
Only IMGT available species/group are shown in the drop-down list.
The gene table can take several seconds to appear, please be patient.

TRAJ segments are designated by a number according to their localisation from 3' to 5'. Ortholog SEGMENTs in human and mouse have the same numbers.
Invariant TRAV11-TRAJ18 (previously Valpha14-Jalpha281), NK T rearrangements (see Gene table: House mouse (Mus musculus) TRAV).

Gene table of house mouse (Mus musculus) TRAJ IMGT group:
IMGT gene nameIMGT allele nameScore for
IMGT allele
confirmation
FctChromosomosal
localization
R T PrIMGT/LIGM-DB reference sequencesIMGT/LIGM-DB sequences from the literature
Clone namesStrainAccession
numbers
Positions
in the sequence
(J-GENE-UNIT)
or J-REGION (*)
Secondary
accession
numbers
Clone namesStrainAccession
numbers
Positions
in the sequence
(J-GENE-UNIT)
or J-REGION (*)
TRAJ1 TRAJ1*01 (8) 14C2 (19.7 cM)
RTPr
---
J1 B10.D2-H2dm1 (9,10) M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP (10) [18] 84366-84421 (11) AE008686 [19] 129/SvJ AE007512 [19] 1656084-1656139
C57BL/6J IMGT000082 [8,9] 1800820-1800875
TRAJ2 TRAJ2*01 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
J2 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 83390-83483 (11) AE008686 [19] 129/SvJ AE007512 [19] 1655108-1655201
C57BL/6J IMGT000082 [8,9] 1799841-1799934
TRAJ2 TRAJ2*02 F 14C2 (19.7 cM) J-alpha26 B10.A M38103 [16] 36-98 *
TRAJ3 TRAJ3*01 (1) 14C2 (19.7 cM) J3 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 82849-82938 (11) AE008686 [19] 129/SvJ AE007512 [19](12) 1654567-1654656
C57BL/6J IMGT000082 [8,9] 1799297-1799386
TRAJ4 TRAJ4*01 (2) 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
J4 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] [18] 81852-81941 (11) AE008686 [19] 129/SvJ AE007512 [19] 1653570-1653659
TRAJ4 TRAJ4*02 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
C57BL/6J CT030634 MAP 182415-182505 C57BL/6J CT573018 complement(133630-133722)
C57BL/6J IMGT000082 [8,9] 1798296-1798386
TRAJ5 TRAJ5*01 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
J6.19 B10.A M38105 [16] MAP 19-108 (11) AE008686 [19] 129/SvJ AE007512 [19] 1651058-1651147
J5 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] [18] 79340-79429
C57BL/6J IMGT000082 [8,9] 1795782-1795871
TRAJ6 TRAJ6*01 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
J6 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 78252-78341 (11) AE008686 [19] 129/SvJ AE007512 [19] 1649970-1650059
C57BL/6J IMGT000082 [8,9] 1794693-1794782
TRAJ7 TRAJ7*01 ORF (13) 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
+-
J7 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 77036-77122 (11) AE008686 [19] 129/SvJ AE007512 [19] 1648754-1648840
C57BL/6J IMGT000082 [8,9] 1793475-1793561
TRAJ8 TRAJ8*01 (8) 14C2 (19.7 cM) B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] [18] 75480-75543 (11) AE008686 [19] 129/SvJ AE007512 [19] 1647198-1647261
TRAJ8 TRAJ8*02 (3) 14C2 (19.7 cM) C57BL/6J IMGT000082 [8,9] MAP 1791923-1791987
TRAJ9 TRAJ9*01 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
BDFLII BALB/c X03761 [11] 77-134 * (11)
TRAJ9 TRAJ9*02 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
C57BL/6J IMGT000082 [8,9] MAP 1791398-1791483 AE008686 [19] 129/SvJ AE007512 [19] 1646674-1646759 (14)
J8 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] [18] 74956-75041
C57BL/Ka X02933 [2] #c 297-352 *
TRAJ11 TRAJ11*01 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
+-
J9 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 72706-72792 (11) AE008686 [19] 129/SvJ AE007512 [19] 1644424-1644510
C57BL/6J IMGT000082 [8,9] 1789144-1789230
TRAJ12 TRAJ12*01 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
J10 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] [18] 72121-72207 (11) AE008686 [19] 129/SvJ AE007512 [19] 1643839-1643925
TRAJ12 TRAJ12*02 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
C57BL/6J IMGT000082 [8,9] MAP 1788558-1788643
TRAJ13 TRAJ13*01 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
J11 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 71310-71394 (11) AE008686 [19] 129/SvJ AE007512 [19] 1643028-1643112
C57BL/6J IMGT000082 [8,9] 1787746-1787830
TRAJ14 TRAJ14*01 (8) 14C2 (19.7 cM) B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 70680-70741 (11) AE008686 [19] 129/SvJ AE007512 [19] 1642398-1642459
C57BL/6J IMGT000082 [8,9] 1787116-1787177
TRAJ15 TRAJ15*01 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
J12 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 69986-70073 (11) AE008686 [19] 129/SvJ AE007512 [19] 1641704-1641791
C57BL/6J IMGT000082 [8,9] 1786427-1786514
TRAJ16 TRAJ16*01 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
J-alpha84 B10.D2-H2dm1 X03057 [32] MAP 53-141 (11) AE008686 [19] 129/SvJ AE007512 [19] 1640419-1640507
J13 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] [18] 68701-68789
C57BL/6J IMGT000082 [8,9] 1785139-1785227
TRAJ17 TRAJ17*01 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
J14 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 67342-67432 (11) AE008686 [19] 129/SvJ AE007512 [19] 1639060-1639150
C57BL/6J IMGT000082 [8,9] 1783780-1783870
TRAJ18 TRAJ18*01 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
J15 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 66344-66437 (11) AE008686 [19] 129/SvJ AE007512 [19] 1638062-1638155
C57BL/6J IMGT000082 [8,9] 1782782-1782875
TRAJ19 TRAJ19*01 ORF (15) 14C2 (19.7 cM) B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 65960-66043 (11) AE008686 [19] 129/SvJ AE007512 [19] 1637678-1637761
C57BL/6J IMGT000082 [8,9] 1782396-1782479
TRAJ20 TRAJ20*01 (4) 14C2 (19.7 cM) B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 65012-65098 (11) AE008686 [19] 129/SvJ AE007512 [19] 1636730-1636816
C57BL/6J IMGT000082 [8,9] 1781447-1781531
TRAJ21 TRAJ21*01 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
J16 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 64359-64443 (11) AE008686 [19] 129/SvJ AE007512 [19] 1636077-1636161
C57BL/6J IMGT000082 [8,9] 1780795-1780879
TRAJ21 TRAJ21*02 (F) 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
C57BL/10 X52448 [1] #c 363-416 *
TRAJ22 TRAJ22*01 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
J17 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 62825-62912 (11) AE008686 [19] 129/SvJ AE007512 [19] 1634543-1634630
C57BL/6J IMGT000082 [8,9] 1779253-1779340
TRAJ23 TRAJ23*01 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
J18 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 61658-61745 (11) AE008686 [19] 129/SvJ AE007512 [19] 1633376-1633463
C57BL/6J IMGT000082 [8,9] 1778086-1778173
TRAJ24 TRAJ24*01 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
J19 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] [18] 61216-61305 (11) AE008686 [19] 129/SvJ AE007512 [19] 1632934-1633023
TRAJ24 TRAJ24*02 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
C57BL/6J IMGT000082 [8,9] MAP 1777643-1777735
TRAJ25 TRAJ25*01 ORF (16) 14C2 (19.7 cM) B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] [18] 60393-60477 (11) AE008686 [19] 129/SvJ AE007512 [19] 1632111-1632195
TRAJ25 TRAJ25*02 ORF (5) 14C2 (19.7 cM) C57BL/6J IMGT000082 [8,9] MAP 1776820-1776904
TRAJ26 TRAJ26*01 (17) 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
C57BL/6J IMGT000082 [8,9] MAP 1776495-1776584 AE008686 [19] 129/SvJ AE007512 [19] 1631787-1631873
J20 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] [18] 60069-60155
TRAJ27 TRAJ27*01 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
J21 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 57885-57971 (11) AE008686 [19] 129/SvJ AE007512 [19] 1629603-1629689
C57BL/6J IMGT000082 [8,9] 1774308-1774394
TRAJ28 TRAJ28*01 F 14C2 (19.7 cM)
RTPr
+
J1031 Std:ddY X17177 [28] MAP 118-210 (11) AE008686 [19] 129/SvJ AE007512 [19] 1628960-1629052
J22 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] [18] 57242-57334
C57BL/6J IMGT000082 [8,9] 1773666-1773758
TRAJ29 TRAJ29*01 ORF (18) 14C2 (19.7 cM) B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 56526-56613 (11) AE008686 [19] 129/SvJ AE007512 [19] 1628244-1628331
C57BL/6J IMGT000082 [8,9] 1772951-1773038
TRAJ30 TRAJ30*01 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
J23 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 55449-55535 (11) AE008686 [19] 129/SvJ AE007512 [19] 1627167-1627253
C57BL/6J IMGT000082 [8,9] 1771871-1771957
TRAJ31 TRAJ31*01 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
J24 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 53479-53563 (11) AE008686 [19] 129/SvJ AE007512 [19] 1625197-1625281
C57BL/6J IMGT000082 [8,9] 1769900-1769984
TRAJ31 TRAJ31*02 (F) 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
M16677 [24] (19) #c 296-351 * BALB/c AY639036 [5,12] (19) #c 344-399 *
TRAJ32 TRAJ32*01 F 14C2 (19.7 cM)
RTPr
++
J-alphaTT11 B10.D2-H2dm1 X02858 [32] MAP 167-260 (11) AE008686 [19] 129/SvJ AE007512 [19] 1623406-1623499
J25 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] [18] 51688-51781
C57BL/6J IMGT000082 [8,9] 1768106-1768199
TRAJ32 TRAJ32*02 (F) 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
FVB/N BC030392 [25] (19) #c 353-416 * M31647 [14] (19) #c 445-507 *
X01133 [6] (19) #c 358-411 *
BALB/c AY639038 [5,12] (19) #c 347-399 *
TRAJ33 TRAJ33*01 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
J26 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 50950-51034 (11) AE008686 [19] 129/SvJ AE007512 [19] 1622668-1622752
C57BL/6J IMGT000082 [8,9] 1767363-1767447
TRAJ34 TRAJ34*01 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
J1 BALB/c X02862 [13] 38-95 * (11)
TRAJ34 TRAJ34*02 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
J27 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 50291-50376 AE008686 [19] 129/SvJ AE007512 [19] 1622009-1622094
B10.S/9R M20875 [20] #c 331-388 *
C57BL/6J IMGT000082 [8,9] 1766704-1766789
TRAJ35 TRAJ35*01 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
J-alphapHDS58 B10.D2-H2dm1 X03056 [32] MAP 740-832 (11) AE008686 [19] 129/SvJ AE007512 [19] 1621084-1621176
J28 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] [18] 49366-49458
C57BL/6J IMGT000082 [8,9] 1765779-1765871
TRAJ35 TRAJ35*02 (20) 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
J2 BALB/c X02843 [13] 29-91 *
TRAJ36 TRAJ36*01 (21) 14C2 (19.7 cM)
RTPr
---
J29 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 47995-48085 (11) AE008686 [19] 129/SvJ AE007512 [19] 1619713-1619803
C57BL/6J IMGT000082 [8,9] 1764407-1764497
TRAJ37 TRAJ37*01 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
J30 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 47112-47199 (11) AE008686 [19] 129/SvJ AE007512 [19] 1618830-1618917
C57BL/6J IMGT000082 [8,9] 1763523-1763610
TRAJ38 TRAJ38*01 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
J31 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 46168-46257 (11) AE008686 [19] 129/SvJ AE007512 [19] 1617886-1617975
C57BL/6J IMGT000082 [8,9] 1762579-1762668
TRAJ39 TRAJ39*01 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
J32 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 45556-45646 (11) AE008686 [19] 129/SvJ AE007512 [19] 1617274-1617364
C57BL/6J IMGT000082 [8,9] 1761967-1762057
TRAJ40 TRAJ40*01 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
J-alpha19 B10.D2-H2dm1 X03058 [32] MAP 273-361 (11) AE008686 [19] 129/SvJ AE007512 [19] 1615237-1615325
J33 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] [18] 43519-43607
C57BL/6J IMGT000082 [8,9] 1759926-1760014
TRAJ41 TRAJ41*01 ORF (22) 14C2 (19.7 cM) B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 41870-41952 (11) AE008686 [19] 129/SvJ AE007512 [19] 1613588-1613670
C57BL/6J IMGT000082 [8,9] 1758276-1758358
TRAJ42 TRAJ42*01 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
J34 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 41372-41463 (11) AE008686 [19] 129/SvJ AE007512 [19] 1613090-1613181
C57BL/6J IMGT000082 [8,9] 1757778-1757869
TRAJ42 TRAJ42*02 (F) 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
C57BL/6 M16675 [24] #c 343-402 *
TRAJ43 TRAJ43*01 F 14C2 (19.7 cM)
RTPr
+
J35 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 40333-40417 (11) AE008686 [19] 129/SvJ AE007512 [19] 1612051-1612135
C57BL/6J IMGT000082 [8,9] 1756747-1756831
TRAJ43 TRAJ43*02 (F) 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
DBA/2 X55823 [10] #c 209-262 *
TRAJ44 TRAJ44*01 ORF (23) 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
J36 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 39284-39372 (11) AE008686 [19] 129/SvJ AE007512 [19] 1611002-1611090
C57BL/6J IMGT000082 [8,9] 1755695-1755783
TRAJ45 TRAJ45*01 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
J-alpha80 B10.D2-H2dm1 X02859 [32] MAP 242-332 (11) AE008686 [19] 129/SvJ AE007512 [19] 1610140-1610230
J37 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] [18] 38422-38512
C57BL/6J IMGT000082 [8,9] 1754833-1754923
TRAJ45 TRAJ45*02 (F) 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
M34206 [27] (19) #c 279->333 * M55635 [21] (19) #c 302->351 *
TRAJ46 TRAJ46*01 (6) 14C2 (19.7 cM) J38 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] [18] 37930-38021 (11) AE008686 [19] 129/SvJ AE007512 [19] 1609648-1609739
TRAJ46 TRAJ46*02 (4) 14C2 (19.7 cM) C57BL/6J IMGT000082 [8,9] MAP 1754341-1754431
TRAJ47 TRAJ47*01 ORF (24) 14C2 (19.7 cM) J39 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] [18] 37394-37478 (11) AE008686 [19] 129/SvJ AE007512 [19] 1609112-1609196
TRAJ47 TRAJ47*02 F 14C2 (19.7 cM) C57BL/6J IMGT000082 [8,9] MAP 1753805-1753889
TRAJ48 TRAJ48*01 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
J40 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 35408-35496 (11) AE008686 [19] 129/SvJ AE007512 [19] 1607126-1607214
C57BL/6J IMGT000082 [8,9] 1751814-1751901
TRAJ49 TRAJ49*01 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
J-alpha65 B10.D2-H2dm1 X03059 [32] MAP 187-273 (11) AE008686 [19] 129/SvJ AE007512 [19] 1606008-1606094
J41 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] [18] 34290-34376
C57BL/6J IMGT000082 [8,9] 1750691-1750777
TRAJ50 TRAJ50*01 F 14C2 (19.7 cM)
RTPr
++
J42 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 33199-33289 (11) AE008686 [19] 129/SvJ AE007512 [19] 1604917-1605007
C57BL/6J IMGT000082 [8,9] 1749595-1749685
TRAJ51 TRAJ51*01 (8) 14C2 (19.7 cM) B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] [18] 31851-31920 (11) AE008686 [19] 129/SvJ AE007512 [19] 1603569-1603638
TRAJ51 TRAJ51*02 (7) 14C2 (19.7 cM) C57BL/6J IMGT000082 [8,9] MAP 1748244-1748314
TRAJ52 TRAJ52*01 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
J44 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 30928-31021 (11) AE008686 [19] 129/SvJ AE007512 [19] 1602646-1602739
C57BL/6J IMGT000082 [8,9] 1747321-1747414
TRAJ53 TRAJ53*01 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
J45 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 28254-28347 (11) AE008686 [19] 129/SvJ AE007512 [19] 1599972-1600065
C57BL/6J IMGT000082 [8,9] 1744649-1744742
TRAJ54 (26) TRAJ54*01 (21) 14C2 (19.7 cM) J46 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 27604-27691 (11) AE008686 [19] 129/SvJ AE007512 [19] 1599322-1599409
C57BL/6J IMGT000082 [8,9] 1743995-1744082
TRAJ55 TRAJ55*01 (25) 14C2 (19.7 cM)
RTPr
+
B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 27055-27145 (11) AE008686 [19] 129/SvJ AE007512 [19] 1598773-1598863
C57BL/6J IMGT000082 [8,9] 1743444-1743534
TRAJ56 TRAJ56*01 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
J47 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 24879-24969 (11) AE008686 [19] 129/SvJ AE007512 [19] 1596597-1596687
C57BL/6J IMGT000082 [8,9] 1741268-1741358
TRAJ57 TRAJ57*01 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
J48 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 24122-24212 (11) AE008686 [19] 129/SvJ AE007512 [19] 1595840-1595930
C57BL/6J IMGT000082 [8,9] 1740512-1740602
TRAJ58 TRAJ58*01 F 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
++
J49 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 22898-22988 (11) AE008686 [19] 129/SvJ AE007512 [19] 1594616-1594706
C57BL/6J IMGT000082 [8,9] 1739285-1739375
TRAJ59 TRAJ59*01 (4) 14C2 (19.7 cM) B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 21751-21840 (11) AE008686 [19] 129/SvJ AE007512 [19] 1593469-1593558
C57BL/6J IMGT000082 [8,9] 1738138-1738227
TRAJ60 TRAJ60*01 (21) 14C2 (19.7 cM) B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 21552-21632 (11) AE008686 [19] 129/SvJ AE007512 [19] 1593270-1593350
C57BL/6J IMGT000082 [8,9] 1737939-1738019
TRAJ61 TRAJ61*01 (21) 14C2 (19.7 cM)
R αT αPr αR δT δPr δ
---
J50 B10.D2-H2dm1 M64239 [2-4,6,11,13,15,17,22,26,29-31,33] MAP [18] 20624-20723 (11) AE008686 [19] 129/SvJ AE007512 [19] 1592342-1592441
C57BL/6J IMGT000082 [8,9] 1737010-1737109
IMGT notes:
  1. noncanonical J-HEPTAMER: TGGACTG instead of CACTGTG, noncanonical J-NONAMER: GGCTTCTTC instead of GGTTTTTGT, noncanonical DONOR-SPLICE: tat instead of ngt
  2. frameshift in J-REGION:defectuous DONOR-SPLICE 'GT' instead of 'NGT' due to the deletion of one nucleotide g between positions 50 and 51 in J-REGION. The four amino acids in 3? are in a reading frame different from the one expected (?LCAH? instead of ?AVCP?).
  3. no DONOR-SPLICE, no J-MOTIF
  4. frameshift in J-REGION: insertion of 1 nt causing defectuous DONOR-SPLICE
  5. noncanonical J-NONAMER: tggttttga instead of ggtttttgt
  6. Defective DONOR-SPLICE (NNGT instead of NGT, with splicing occurring before G in both cases).
  7. frameshift in J-REGION: deletion of 1 nt causing defectuous DONOR-SPLICE, no DONOR-SPLICE
  8. Pseudogene because germline J-GENE only identified by the presence of the recombination signal upstream of an open reading frame, but without donor splicing site in 5' and without the conserved J-MOTIF Phe (or Trp)-Gly-X-Gly motif.
  9. B10.D2-H2dm1 is a congenic strain, B10 is the abbreviated symbol of C57BL/10 and D2 the abbreviated symbol of DBA/2J
  10. Strain of M64239 is according to [1,18]. The flat file up to March 2000 has no information on the strain. Strain BALB/c was added in EMBL flat file in release 62 (03 March 2000) but without explanation.
  11. These J-GENEs have been identified by Dominique Scaviner (LIGM).
  12. The allele TRAJ3*01 has been declared ORF in annotations. However, it was never found rearranged or transcribed and was therefore considered as a pseudogene.
  13. In coding_start2, the one used by the human TRAJ7 gene, non canonical J-MOTIF: Leu-Gly-X-Gly instead of Phe-Gly-X-Gly. In coding_start1, canonical J-MOTIF: Phe-Gly-X-Gly, but defective DONOR-SPLICE (NNGT instead of NGT, with splicing occurring before G in both cases).
  14. frameshift in J-REGION: deletion of 1 nt causing defectuous DONOR-SPLICE
  15. Non canonical J-HEPTAMER: AAATCTG instead of CACTGTG, and non canonical J-MOTIF: Ser-Gly-X-Glu instead of Phe-Gly-X-Gly.
  16. Non canonical J-HEPTAMER: CACTGTA instead of CACTGTG, and non canonical J-MOTIF: Phe-Gly-X-Trp instead of Phe-Gly-X-Gly.
  17. The deletion of c26 in the TRAJ26 J-REGION, in M64239 and AE007512, is probably due to a sequencing error. The functionality of TRAJ26 was changed (on 19/01/2007) from pseudogene (due to a frameshift) to functional.
  18. Non canonical J-NONAMER: GGGGATGAG instead of GGTTTTTGT, and non canonical J-MOTIF: Leu-Gly-X-Glu instead of Phe-Gly-X-Gly.
  19. Potentiel allele base on the finding of several sequences in cDNA (IMGT Annotation: Yan Wu, Géraldine Folch, Marie-Paule Lefranc 19/01/2009).
  20. INSERTION of one nucleotide G, between positions 6 and 7. This INSERTION may represent a sequencing error. This INSERTION may represent a sequencing error. There is also the possibility that the nucleotide deletion in 5' of the J-REGION, during the V-J rearrangement, deletes the nucleotides up to the extra G included as in the productive cDNA X01134 (N. Bosc and M.-P. Lefranc, 28/01/2002).
  21. STOP-CODON in J-REGION.
  22. Non canonical J-NONAMER: GAGGTTGTG instead of GGTTTTTGT, and non canonical J-MOTIF: Leu-Ala-X-Gly instead of Phe-Gly-X-Gly. Defective DONOR-SPLICE (GTN instead of NGT, with splicing occurring before G in both cases).
  23. Non canonical J-MOTIF: Leu-Gly-X-Gly instead of Phe-Gly-X-Gly.
  24. Non canonical J-MOTIF: Cys-Gly-X-Gly instead of Phe-Gly-X-Gly.
  25. Frameshift in J-REGION.
  26. LIGM annotation based on reference (PMID:1505953 and 1505954).
IMGT references:
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  3. Baer R. et al., Organization of the T-cell receptor alpha-chain gene and rearrangement in human T-cell leukaemias, Mol. Biol. Med, vol. 3, no. 3, 1986, pp. 265-277. PUBMED: 3016457
  4. Becker D.M. et al., Variability and repertoire size of T-cell receptor V alpha gene segments, Nature, vol. 317, no. 6036, 1985, pp. 430-434. DOI: 10.1038/317430a0
  5. Berlo S.E. et al., T Cell Receptor Transgenic Mice Recognize Human Cartilage Proteoglycan Aggrecan, Unpublished.
  6. Chien Y.-H. et al., A third type of murine T-cell receptor gene, Nature, vol. 312, no. 5989, 1984, pp. 31-35. DOI: 10.1038/312031a0
  7. Chien Y.H. et al., A new T-cell receptor gene located within the alpha locus and expressed early in T-cell differentiation, Nature, vol. 327, no. 6124, 1987, pp. 677-682. DOI: 10.1038/327677a0
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  17. Iwashima M. et al., Variable region (V delta) gene segment most frequently utilized in adult thymocytes is 3' of the constant (C delta) region, Proc. Natl. Acad. Sci. U.S.A, vol. 85, no. 21, 1988, pp. 8161-8165. PUBMED: 3263646
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  23. Saito H. et al., A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes, Nature, vol. 312, no. 5989, 1984, pp. 36-40. DOI: 10.1038/312036a0
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