IMGT Repertoire (IG and TR)

pseudogene no INIT-CODON: aag instead of atg, DELETION of 12 nt in CDR1-IMGT, STOP-CODON in FR2-IMGT at codon 45 and INSERTION of 6 nt in CDR2-IMGT, no CONSERVED-TRP
frameshifts in V-REGION: several insertions and deletions
pseudogene because DELETION of 12 nt in CDR1-IMGT, STOP-CODON in FR2-IMGT at codon 45 and INSERTION of 6 nt in CDR2-IMGT
frameshifts in V-REGION: several insertions and deletions, frameshift in L-PART1: insertion of 1 nt causing defectuous DONOR-SPLICE
Pseudogene because of STOP-CODONs and frameshifts in FR1-IMGT and FR3-IMGT
Pseudogene because of STOP_CODON at position 84B in FR3-IMGT
STOP-CODON in V-REGION: position 83
functional however there is an INSERTION of 12 nucleotides CCCAGCTGGAGG in FR3-IMGT (between positions 293 and 294 in IMGT unique numbering). This INSERTION is a duplication of positions 280-293 and may represent a sequencing error.
pfunctional however there is an INSERTION of 12 nucleotides CCCAGCTGGAGG in FR3-IMGT (between positions 293 and 294 in IMGT unique numbering). This INSERTION is a duplication of positions 280-293 and may represent a sequencing error.
pseudogene because no L-PART1 and STOP_CODONs at position 58 in CDR2-IMGT and at position 99 in FR3-IMGT
several STOP-CODON in V-REGION, no CONSERVED-TRP: STOP-CODON instead of Trp, no L-PART1
pseudogene because no L-PART1, STOP_CODONs at position 58 in CDR2-IMGT and at position 100 in FR3-IMGT, and 2nd_CYS replaced by a STOP_CODON
several STOP-CODON in V-REGION, no 2nd-CYS: STOP-CODON instead of Cys, no L-PART1
pseudogene because no L-PART1, In frame STOP-CODONs at codon 58 in CDR2-IMGT (positions 172-174 in IMGT unique numbering), at codons 99 and 104 in FR3-IMGT (positions 295-297 and 310-312), the 2nd-CYS is not conserved and no V-NONAMER.
pseudogene because DELETIONs leading to frameshift in FR1-IMGT and FR3-IMGT, no CONSERVED_TRP and no L-PART1
No L-PART1, in frame STOP-CODON at codon 5 in FR1-IMGT (positions 13-15 in IMGT unique numbering) and DELETION of 1 nucleotide in FR1-IMGT (position 42), DELETION of 6 nucleotides in frame (positions 229-234) and of 16 nucleotides in FR3-IMGT (position 262-277), STOP-CODON at codon 99 in FR3-IMGT (positions 295-297).
no L-PART2, truncated pseudogene, frameshifts in V-REGION: several insertions and deletions
Frameshift in V-REGION
because unusual V-HEPTAMER: cacactg instead of cacagtg
between Np and Tcrd
between p and Hbb
pseudogene because DELETION of one nucleotide between position 83/84 at codon 28 in CDR1-IMGT leading to a frameshift
no INIT-CODON: Leu instead of Met
Frameshift in FR3-IMGT
spliced
Pseudogene because DELETION of 1 nucleotide between position 299/300 at codon 100 in FR3-IMGT leading to a frameshift
noncanonical V-NONAMER: acactgacc instead of acaaaaact
10 AA missing in CDR2-IMGT and FR3-IMGT
pseudogene because insertion of one nucleotide in position 7 leads to a frameshift in L-PART1
Unusual V-HEPTAMER sequence: cacactg instead of cacagtg, functional because it has been found rearranged
noncanonical V-HEPTAMER: caccatg instead of cacagtg
STOP-CODON in V-REGION: position 25
because unusual V-HEPTAMER: cacagcg instead of cacagtg
pseudogene because no L-PART1, no L-PART2, STOP_CODON at position 40 in FR2-IMGT and DELETION of 9 nt leading to a frameshift in FR3-IMGT
V-REGION is partial: AA 1 to 4 are missing (partial FR1-IMGT), in frame STOP-CODON at codon 40 (positions 118-120 in IMGT unique numbering) and DELETION of 1 nucleotide in FR2-IMGT (position 149).
STOP-CODON in V-REGION: position 40, no L-PART2, truncated pseudogene
frameshift in V-REGION: insertion of 2 nt in FR1-IMGT
pseudogene because DELETION in V-REGION: AA 43 to 91 are missing (partial FR2-IMGT, no CDR2-IMGT and partial FR3-IMGT), DELETION of one nt in FR1-IMGT leading to a frameshift
no INIT-CODON: Val instead of Met, frameshifts in V-REGION: several insertions and deletions, truncated pseudogene, no V-RS
Frameshift in V-REGION, deletion AA in FR2-IMGT and FR3-IMGT
pseudogene because DELETION in V-REGION: AA 43 to AA 91 are missing (partial FR2-IMGT, no CDR2-IMGT and partial FR3-IMGT), DELETION of one nt in FR1-IMGT leading to a frameshift
noncanonical V-NONAMER:cccaaaccc instead of acacaaacc
noncanonical V-HEPTAMER: cacggta instead of cacagtg, however this V-GENE has been
pseudogene because STOP_CODON in FR1-IMGT, DELETION of 12 nucleotides in FR2-IMGT leading to a frameshift and 2nd_CYS replaced by a STOP_CODON
noncanonical V-HEPTAMER: cacggta instead of cacagtg, however this V-GENE has been found rearranged
pseudogene because 2 STOP-CODONs in FR1-IMGT
pseudogene because in frame STOP-CODONs at codon 4 and 11 in FR1-IMGT
noncanonical V-NONAMER: caaaatctg instead of acacaaacc
because frameshift in V-REGION
several STOP-CODON in V-REGION, frameshift in L-PART2: deletion of 1 nt
pseudogene because INSERTION of 13 nt in FR3-IMGT leading to a frameshift
frameshift in V-REGION: insertion of 13 nt in FR3-IMGT
B10.A is a congenic strain (see MGD for Strain Nomenclature Guidelines), B10 is the abbreviated symbol of C57BL/10.
Sequence submitted to EMBL by IMGT curators (Bosc, N., 21/04/2001).
INSERTION of 12 nucleotides CCCAGCTGGAGG in FR3-IMGT (between positions 293 and 294 in IMGT unique numbering). This INSERTION is a duplication of positions 280-293 (Bosc, N., IMGT comment, 01/02/2001) and may represent a sequencing error.
No L-PART1, in frame STOP-CODON in V-REGION.
V-REGION is partial: AA 1 to 22 are missing (partial FR1-IMGT).
V-REGION is partial: AA 1 is missing (partial FR1-IMGT).
V-REGION is partial: AA 1 to 15 are missing (partial FR1-IMGT).
V-REGION is partial: AA 1 to 10 are missing (partial FR1-IMGT).
V-REGION is partial: AA 1 to 8 are missing (partial FR1-IMGT).
V-GENE is partial: partial V-SPACER and no V-NONAMER.
Potentiel allele base on the finding of several sequences in cDNA (IMGT Annotation: Yan Wu, Géraldine Folch, Marie-Paule Lefranc 19/01/2009).
V-REGION is partial: AA 1 to 9 are missing (partial FR1-IMGT).
V-REGION is partial: AA 1 to 11 are missing (partial FR1-IMGT).
V-REGION is partial: AA 1 to 44 are missing (no FR1-IMGT, no CDR1-IMGT, partial FR2-IMGT).
V-REGION is partial: AA 1 to 25 are missing (partial FR1-IMGT).
V-REGION is partial: AA 1 to 69 are missing (no FR1-IMGT, no CDR1-IMGT, no FR2-IMGT, no CDR2-IMGT, partial FR3-IMGT).
V-REGION is partial: AA 1 to 19 are missing (partial FR1-IMGT).
V-REGION is partial: AA 1 to 51 are missing (no FR1-IMGT, no CDR1-IMGT and partial FR2-IMGT).
Although the V-HEPTAMER is unusual (CACAGTA instead of CACAGTG), the gene has been found rearranged and is therefore functional.
V-REGION is partial: AA 1 to 56 are missing (no FR1-IMGT, no CDR1-IMGT, no FR2-IMGT and partial CDR2-IMGT).
Sterile transcript
V-REGION is partial: AA 1 to 43 are missing (no FR1-IMGT, no CDR1-IMGT and partial FR2-IMGT).
V-REGION is partial: AA 1 and 2 are missing (partial FR1-IMGT).
V-REGION is partial: AA 1 to 38 are missing (no FR1-IMGT, no CDR1-IMGT and no FR2-IMGT).
Although the V-HEPTAMER is unusual (CACACTG instead of CACAGTG), the gene has been found rearranged and is therefore functional.
X53732 differs by one undefined nucleotide at codon 7 (position 20 in IMGT unique numbering).
For the TRAV11 subgroup, sequences of the TRAV11D gene cannot be differentiated from those of the TRAV11 gene, when these sequences are not mapped. These unmapped sequences are therefore described as "TRAV11 alleles" and compared to the allele *01 of TRAV11 (AC005240). However it is not excluded that some of these "alleles" belong exclusively to the TRAV11D gene.
Although the V-HEPTAMER is unusual (CACCATG instead of CACAGTG), the gene has been found rearranged and is therefore functional.
It is not known if this sequence is an allele of TRAV11 or of TRAV11D (see note (49)).
V-REGION is partial: AA 1 and 2, 106 and 107 are missing (partial FR1-IMGT and partial CDR3-IMGT). It is not known if this sequence is an allele of TRAV11 or of TRAV11D (see note (49)).
It is not known if this sequence is an allele of TRAV11 or of TRAV11D.
In frame STOP-CODON at codon 25 in FR1-IMGT (positions 73-75 in IMGT unique numbering). It is not known if this sequence is an allele of TRAV11 or of TRAV11D (see note (49)).
ORF because unusual V-HEPTAMER sequence: CACAGCG instead of CACAGTG.
V-REGION is partial: AA 1 to 42 are missing (no FR1-IMGT, no CDR1-IMGT and partial FR3-IMGT), DELETION of 3 nucleotides in frame in FR3-IMGT (positions 279-281 in IMGT unique numbering, S93 is encoded by TCG instead of TCA) .
V-REGION is partial: AA 1 to 3 are missing (partial FR1-IMGT).
V-REGION is partial: AA 1 to 17 are missing (partial FR1-IMGT).
ORF because unusual V-HEPTAMER sequence: GAGGGTG instead of CACAGTG.
Following a question from M. Le Moine, the assignment of L77149 and L77150 was revised. L77149 has been assigned to TRAV14-1*01 (instead of TRAV14D-1*01) and L77150 has been assigned to TRAV14D-1*01 (instead of TRAV14-1*01) (J Jabado-Michaloud and M-P. Lefranc, 12/05/2021).
In frame STOP-CODONs at codon 58 in CDR2-IMGT (positions 172-174 in IMGT unique numbering) and at codon 99 in FR3-IMGT (positions 295-297).
ORF because no CONSERVED-TRP
U04312 and AC005402 have the same V-REGION but L-PART1 and L-PART2 are different.
V-REGION is partial: AA 1 to 27 are missing (no FR1-IMGT and partial CDR1-IMGT).
The V-REGION of allele TRAV14-3*01 is 100% identical to the V-REGION of allele TRAV14D-3/DV8*08.
The V-REGION of allele TRAV14D-3/DV8*01 is 100% identical to the V-REGION of allele TRAV14N-3*01.
V-GENE is partial (no L-PART1, no L-PART2), and V-REGION is partial: AA 1 is absent (FR1-IMGT is partial).
The V-REGION of allele TRAV15D-2/DV6D-2*03 is 100% identical to the V-REGION of allele TRAV15N-2*01.
The V-REGION of allele TRAV16*01 is 100% identical to the V-REGION of allele TRAV16D/DV11*02.
Although the V-HEPTAMER is unusual (CACGGTA instead of CACAGTG), the gene has been found rearranged and therefore is functional.
Several STOP-CODON in V-REGION, frameshift in V-REGION: deletion of 1 nt in FR1-IMGT
pseudogene because INIT-CODON not conserved in L-PART1: atc instead of atg
ORF because the 1st-CYS is not conserved, V-REGION is partial: AA 1 is missing (partial FR1-IMGT).

IMGT references: ↑

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IMGT Repertoire (IG and TR)

Dynamic gene tables per IMGT group and per species (IMGT/GeneTables)

Gene table legend:

IMGT notes: ↑

IMGT references: ↑

IMGT Repertoire (IG and TR)

Dynamic gene tables per IMGT group and per species (IMGT/GeneTables)

Version 1.4

Version 1.3

Version 1.2

Version 1.1

Version 1.0

Gene table legend:

IMGT notes: ↑

IMGT references: ↑