Citing IMGT dynamic tools: Sanou G., Zeitoun G. et al. IMGT® at scale: FAIR, Dynamic and Automated Tools for Immune Locus Analysis, Nucleic Acids Research. 2025;,gkaf1024. doi: 10.1093/nar/gkaf1024 (Free Article) PMID: 41091930.
Program version: v. 

Add information about removed genes/alleles.
May 15th, 2025.

Add the possibility to obtain a gene table per strain (for mouse now and for other species later) and allotypes/isotypes for human.
September 25th, 2024.

Bibliographical references in alphabetic order, small design changes and addition of "NL" for non-localized gene.
June 14th, 2024.

Addition of 'Score for IMGT allele confirmation' as well as NCBI TPA accession numbers.
September 20th, 2023.

Implementation of the dynamic gene table.

Gene table legend:

"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) rearranged (R), transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene, when the data have been confirmed by several studies.

Functionality is shown in parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.

IMGT allele confirmation: A scoring system is employed to indicate the number of IMGT/LIGM-DB reference sequences and other sequences from the literature in which an IG or TR gene allele has been identified and annotated.

Removed genes/alleles
If a gene/allele existence or name has to be changed, the old name or gene/allele would be deleted and its name won't be reused. They are kept in the gene table for historical reasons.
A single star ()
indicates that an IG or TR gene allele is annotated in the reference sequence only.
Two stars ()
indicate that an IG or TR gene allele is annotated in its reference sequence and in one sequence from the literature.
Three stars ()
indicate that an IG or TR gene allele is annotated in its reference sequence and in at least two sequences from the literature.
In the Excel file, the stars are represented by the plus symbol (+).

Click on:
  • IMGT gene name to get the corresponding IMGT/GENE-DB entry (link).
  • IMGT allele name to see the corresponding Alignments of alleles (link).
  • Accession number to get the corresponding IMGT/LIGM-DB entry (link).
  • MAP: mapped sequences. Click to access GENE-DB «LOCALIZATION IN GENOME ASSEMBLIES» (link).
  • [number] to access the corresponding IMGT reference (popover).
  • (number) to see the corresponding IMGT note (popover).
Options:
  • You can show/hide columns (), download data () or put the table in fullscreen () using buttons.
See also (IMGT Scientific chart):
Select a species and a IMGT group to get the gene table:
Only IMGT available species/group are shown in the drop-down list.
The gene table can take several seconds to appear, please be patient.
Gene table of human (Homo sapiens) TRBC IMGT group:
IMGT gene nameIMGT allele nameScore for
IMGT allele
confirmation		FctChromosomosal
localization		ExonsR T PrIMGT/LIGM-DB reference sequencesIMGT/LIGM-DB sequences from the literature
Clone namesAccession
numbers		Positions
in the sequence		Secondary
accession
numbers		Clone namesAccession
numbers		Positions
in the sequence
TRBC1 TRBC1*01 F 7q34 EX1
RTPr
++
 Cbeta1 M12887 [12] ° 213-599 CM092208.1 IMGT000287 [6] 543163-543549
Cbeta1 M14157 [11] ° 171-557
TRBC1 TRBC1*01 F 7q34 EX2
RTPr
++
 Cbeta1 M12887 [12] ° 1041-1058 CM092208.1 IMGT000287 [6] 543991-544008
Cbeta1 M14157 [11] ° 999-1016
TRBC1 TRBC1*01 F 7q34 EX3
RTPr
++
 Cbeta1 M12887 [12] ° 1211-1317 CM092208.1 IMGT000287 [6] 544161-544267
Cbeta1 M14157 [11] ° 1169-1275
TRBC1 TRBC1*01 F 7q34 EX4
RTPr
++
 Cbeta1 M12887 [12] ° 1640-1657 CM092208.1 IMGT000287 [6] 544590-544607
Cbeta1 M14157 [11] ° 1598-1615
TRBC1 TRBC1*02 F 7q34 EX1 Cbeta1 L36092 [7-10] (1) 645749-646135 U66061 [7-9]
TRBC1 TRBC1*02 F 7q34 EX2 Cbeta1 L36092 [7-10] (1) 646577-646594 U66061 [7-9]
TRBC1 TRBC1*02 F 7q34 EX3 Cbeta1 L36092 [7-10] (1) 646747-646853 U66061 [7-9]
TRBC1 TRBC1*02 F 7q34 EX4 Cbeta1 L36092 [7-10] (1) 647176-647193 U66061 [7-9]
TRBC1 TRBC1*03 F 7q34 EX1 CM000669.2 IMGT000021 [4,5] MAP 560349-560735 GWHGEYC00000007.1 IMGT000303 [1-3] 563656-564042
TRBC1 TRBC1*03 F 7q34 EX2 CM000669.2 IMGT000021 [4,5] MAP 561177-561194 GWHGEYC00000007.1 IMGT000303 [1-3] 564484-564501
TRBC1 TRBC1*03 F 7q34 EX3 CM000669.2 IMGT000021 [4,5] MAP 561347-561453 GWHGEYC00000007.1 IMGT000303 [1-3] 564654-564760
TRBC1 TRBC1*03 F 7q34 EX4 CM000669.2 IMGT000021 [4,5] MAP 561776-561793 GWHGEYC00000007.1 IMGT000303 [1-3] 565083-565100
TRBC2 TRBC2*01 F 7q34 EX1
RTPr
++
 Cbeta2 M12888 [12] ° MAP 154-540 Cbeta2 M12510 [11] ° 783-1169
TRBC2 TRBC2*01 F 7q34 EX2
RTPr
++
 Cbeta2 M12888 [12] ° MAP 1057-1074 Cbeta2 M12510 [11] ° 1686-1703
TRBC2 TRBC2*01 F 7q34 EX3
RTPr
++
 Cbeta2 M12888 [12] ° MAP 1218-1324 Cbeta2 M12510 [11] ° 1847-1953
TRBC2 TRBC2*01 F 7q34 EX4
RTPr
++
 Cbeta2 M12888 [12] ° MAP 1616-1639 Cbeta2 M12510 [11] ° 2245-2268
TRBC2 TRBC2*02 F 7q34 EX1
RTPr
++
 Cbeta2 L36092 [7-10] (1) 655095-655481 U66061 [7-9] GWHGEYC00000007.1 IMGT000303 [1-3] 573003-573389
TRBC2 TRBC2*02 F 7q34 EX2
RTPr
++
 Cbeta2 L36092 [7-10] (1) 655998-656015 U66061 [7-9] GWHGEYC00000007.1 IMGT000303 [1-3] 573906-573923
TRBC2 TRBC2*02 F 7q34 EX3
RTPr
++
 Cbeta2 L36092 [7-10] (1) 656159-656265 U66061 [7-9] GWHGEYC00000007.1 IMGT000303 [1-3] 574067-574173
TRBC2 TRBC2*02 F 7q34 EX4
RTPr
++
 Cbeta2 L36092 [7-10] (1) 656557-656580 U66061 [7-9] GWHGEYC00000007.1 IMGT000303 [1-3] 574465-574488
TRBC2 TRBC2*03 F 7q34 EX1 CM000669.2 IMGT000021 [4,5] MAP 569696-570082
TRBC2 TRBC2*03 F 7q34 EX2 CM000669.2 IMGT000021 [4,5] MAP 570599-570616
TRBC2 TRBC2*03 F 7q34 EX3 CM000669.2 IMGT000021 [4,5] MAP 570760-570866
TRBC2 TRBC2*03 F 7q34 EX4 CM000669.2 IMGT000021 [4,5] MAP 571158-571181
TRBC2 TRBC2*04 F 7q34 EX1 CM092208.1 IMGT000287 [6] 552511-552897
TRBC2 TRBC2*04 F 7q34 EX2 CM092208.1 IMGT000287 [6] 553414-553431
TRBC2 TRBC2*04 F 7q34 EX3 CM092208.1 IMGT000287 [6] 553575-553681
TRBC2 TRBC2*04 F 7q34 EX4 CM092208.1 IMGT000287 [6] 553973-553996
IMGT notes: ↑
  1. The original L36092 sequence (684973 bp) has been split in EMBL into three sequences of 267156 bp (U66059), 215422 bp (U66060) and 232650 bp (U66061), L36092 has become secondary accession number of U66059, U66060 and U66061. In IMGT, the original sequence L36092 which is fully annotated has also been kept as primary accession number, in addition to U66059, U66060 and U66061.
IMGT references: ↑
  1. Chu et al., Approaching an Error-Free Diploid Human Genome Assembly of East Asian Origin, (misc) bioRxivorg, 2025, DOI: 10.1101/2025.08.01.667781
  2. Chu et al., Direct Submission, Computational Biology, Beijing Institute of Genomics, Chinese Academy of Sciences / China National Center for Bioinformation. Submitted (16-AUG-2025). NGDC, Beijing, 100101, China.
  3. He et al., T2T YAO: A Telomere to telomere Assembled Diploid Reference Genome for Han Chinese, Genomics Proteomics & Bioinformatics 21(6): 1085–1100 (2023), DOI: 10.1016/j.gpb.2023.08.001
  4. Hillier L.W. et al., The DNA sequence of human chromosome 7, Nature, vol. 424, no. 6945, 2003, pp. 157-164. PUBMED: 12853948
  5. Lander,E.S. et al., Initial sequencing and analysis of the human genome, Nature, vol. 409, no. 6822, 2001, pp. 860-921. PUBMED: 11237011
  6. Liao W.W. et al., A draft human pangenome reference, Nature, vol. 617, no. 7960, 2023, pp. 312-324. PUBMED: 37165242
  7. Rowen L. et al., Sequence determination of the human T cell receptor beta locus: Strategy and error analysis, Unpublished.
  8. Rowen L. et al., Sequence variation among several haplotypes in the human T cell receptor beta locus, Unpublished.
  9. Rowen L. et al., The complete 685-kilobase DNA sequence of the human beta T cell receptor locus, Science, vol. 272, no. 5269, 1996, pp. 1755-1762. DOI: 10.1126/science.272.5269.1755
  10. Slightom J.L. et al., Nucleotide sequence analysis of 77.7 kb of the human V beta T-cell receptor gene locus: direct primer-walking using cosmid template DNAs, Genomics, vol. 20, no. 2, 1994, pp. 149-168. DOI: 10.1006/geno.1994.1149
  11. Toyonaga B. et al., Organization and sequences of the diversity, joining, and constant region genes of the human T-cell receptor beta chain, Proc. Natl. Acad. Sci. U.S.A, vol. 82, no. 24, 1985, pp. 8624-8628. PUBMED: 3866244
  12. Tunnacliffe A. et al., Sequence and evolution of the human T-cell antigen receptor beta-chain genes, Proc. Natl. Acad. Sci. U.S.A, vol. 82, no. 15, 1985, pp. 5068-5072. PUBMED: 3860845