Citing IMGT dynamic tools: Sanou G., Zeitoun G. et al. IMGT® at scale: FAIR, Dynamic and Automated Tools for Immune Locus Analysis, Nucleic Acids Research. 2025;,gkaf1024. doi: 10.1093/nar/gkaf1024 (Free Article) PMID: 41091930.
Program version: v. 

Add information about removed genes/alleles.
May 15th, 2025.

Add the possibility to obtain a gene table per strain (for mouse now and for other species later) and allotypes/isotypes for human.
September 25th, 2024.

Bibliographical references in alphabetic order, small design changes and addition of "NL" for non-localized gene.
June 14th, 2024.

Addition of 'Score for IMGT allele confirmation' as well as NCBI TPA accession numbers.
September 20th, 2023.

Implementation of the dynamic gene table.

Gene table legend:

"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) rearranged (R), transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene, when the data have been confirmed by several studies.

Functionality is shown in parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.

IMGT allele confirmation: A scoring system is employed to indicate the number of IMGT/LIGM-DB reference sequences and other sequences from the literature in which an IG or TR gene allele has been identified and annotated.

Removed genes/alleles
If a gene/allele existence or name has to be changed, the old name or gene/allele would be deleted and its name won't be reused. They are kept in the gene table for historical reasons.
A single star ()
indicates that an IG or TR gene allele is annotated in the reference sequence only.
Two stars ()
indicate that an IG or TR gene allele is annotated in its reference sequence and in one sequence from the literature.
Three stars ()
indicate that an IG or TR gene allele is annotated in its reference sequence and in at least two sequences from the literature.
In the Excel file, the stars are represented by the plus symbol (+).

Click on:
  • IMGT gene name to get the corresponding IMGT/GENE-DB entry (link).
  • IMGT allele name to see the corresponding Alignments of alleles (link).
  • Accession number to get the corresponding IMGT/LIGM-DB entry (link).
  • MAP: mapped sequences. Click to access GENE-DB «LOCALIZATION IN GENOME ASSEMBLIES» (link).
  • [number] to access the corresponding IMGT reference (popover).
  • (number) to see the corresponding IMGT note (popover).
Options:
  • You can show/hide columns (), download data () or put the table in fullscreen () using buttons.
See also (IMGT Scientific chart):
Select a species and a IMGT group to get the gene table:
Only IMGT available species/group are shown in the drop-down list.
The gene table can take several seconds to appear, please be patient.
Gene table of human (Homo sapiens) TRBD IMGT group:
IMGT sub­groupIMGT gene nameIMGT allele nameScore for
IMGT allele
confirmation
FctChromosomosal
localization
R T PrIMGT/LIGM-DB reference sequencesIMGT/LIGM-DB sequences from the literature
Clone namesAccession
numbers
Positions
in the sequence
(D-GENE-UNIT)
or D-REGION (*)
Secondary
accession
numbers
Clone namesAccession
numbers
Positions
in the sequence
(D-GENE-UNIT)
or D-REGION (*)
TRBD1TRBD1 TRBD1*01 F 7q34
RTPr
+++
Dbeta1.1 K02545 [4,12] MAP (1) 54-132 X00936 [3] CM000669.2 IMGT000021 [6,7] 554840-554918
CM092208.1 IMGT000287 [8] 537654-537732
GWHGEYC00000007.1 IMGT000303 [1,5] 558147-558225
Dbeta1.1 L36092 [9-11,13] (2) 640240-640318
Dbeta1.1 M14158 [14] 54-132
Dbeta1.1 U66061 [9-11] (2) 187917-187995
TRBD2TRBD2 TRBD2*01 F 7q34
RTPr
+++
Dbeta2.1 X02987 [15] 112-194 CM092208.1 IMGT000287 [8] 547146-547228
GWHGEYC00000007.1 IMGT000303 [1,5] 567639-567721
TRBD2TRBD2 TRBD2*02 F 7q34
RTPr
+++
Dbeta2.1 M14159 [14] MAP 541-623 CM000669.2 IMGT000021 [6,7] 564332-564414
Dbeta2.1 L36092 [9-11,13] (2) 649732-649814
Dbeta2.1 U66061 [9-11] (2) 197409-197491
IMGT notes:
  1. In EMBL, a new accession number K02545 was created, the original accession number X00936 becoming secondary accession number of K02545.
  2. The original L36092 sequence (684973 bp) has been split in EMBL into three sequences of 267156 bp (U66059), 215422 bp (U66060) and 232650 bp (U66061), L36092 has become secondary accession number of U66059, U66060 and U66061. In IMGT, the original sequence L36092 which is fully annotated has also been kept as primary accession number, in addition to U66059, U66060 and U66061.
IMGT references:
  1. Chu et al., Approaching an Error-Free Diploid Human Genome Assembly of East Asian Origin, (misc) bioRxivorg, 2025, DOI: 10.1101/2025.08.01.667781
  2. Chu et al., Direct Submission, Computational Biology, Beijing Institute of Genomics, Chinese Academy of Sciences / China National Center for Bioinformation. Submitted (16-AUG-2025). NGDC, Beijing, 100101, China.
  3. Clark S.P. et al., Identification of a diversity segment of human T-cell receptor beta-chain, and comparison with the analogous murine element, Nature, vol. 311, 1984, pp. 387-389. Patent ID: 85012683
  4. Clark S.P. et al., Identification of a diversity segment of human T-cell receptor beta-chain, and comparison with the analogous murine element, Nature, vol. 311, no. 5984, 1984, pp. 387-389. DOI: 10.1038/311387a0
  5. He et al., T2T YAO: A Telomere to telomere Assembled Diploid Reference Genome for Han Chinese, Genomics Proteomics & Bioinformatics 21(6): 1085–1100 (2023), DOI: 10.1016/j.gpb.2023.08.001
  6. Hillier L.W. et al., The DNA sequence of human chromosome 7, Nature, vol. 424, no. 6945, 2003, pp. 157-164. PUBMED: 12853948
  7. Lander,E.S. et al., Initial sequencing and analysis of the human genome, Nature, vol. 409, no. 6822, 2001, pp. 860-921. PUBMED: 11237011
  8. Liao W.W. et al., A draft human pangenome reference, Nature, vol. 617, no. 7960, 2023, pp. 312-324. PUBMED: 37165242
  9. Rowen L. et al., Sequence determination of the human T cell receptor beta locus: Strategy and error analysis, Unpublished.
  10. Rowen L. et al., Sequence variation among several haplotypes in the human T cell receptor beta locus, Unpublished.
  11. Rowen L. et al., The complete 685-kilobase DNA sequence of the human beta T cell receptor locus, Science, vol. 272, no. 5269, 1996, pp. 1755-1762. DOI: 10.1126/science.272.5269.1755
  12. Siu G. et al., The human T cell antigen receptor is encoded by variable, diversity, and joining gene segments that rearrange to generate a complete V gene, Cell, vol. 37, no. 2, 1984, pp. 393-401. DOI: 10.1016/0092-8674(84)90369-6
  13. Slightom J.L. et al., Nucleotide sequence analysis of 77.7 kb of the human V beta T-cell receptor gene locus: direct primer-walking using cosmid template DNAs, Genomics, vol. 20, no. 2, 1994, pp. 149-168. DOI: 10.1006/geno.1994.1149
  14. Toyonaga B. et al., Organization and sequences of the diversity, joining, and constant region genes of the human T-cell receptor beta chain, Proc. Natl. Acad. Sci. U.S.A, vol. 82, no. 24, 1985, pp. 8624-8628. PUBMED: 3866244
  15. Tunnacliffe A. and Rabbitts T.H, Sequence of the D beta 2-J beta 2 region of the human T-cell receptor beta-chain locus, Nucleic Acids Res, vol. 13, no. 18, 1985, pp. 6651-6661. DOI: 10.1093/nar/13.18.6651