IMGT Repertoire (IG and TR)

✤ : NCBI accession number that correspond to a previously internal IMGT accession number. See the correspondence table.

IMGT notes: ↑

1. insertions in CDR1-IMGT: 5 AA are added
2. frameshift in L-PART2: deletion of 1 nt, several STOP-CODON in V-REGION, frameshift in V-REGION: insertion of 1 nt in FR3-IMGT
3. frameshift in L-PART2: deletion of 1 nt, frameshift in V-REGION: insertion of 1 nt in FR3-IMGT
4. no L-PART1, no L-PART2, frameshift in V-REGION: insertion of 1 nt in FR2-IMGT
5. frameshift in L-PART2: deletion of 1 nt, frameshift in V-REGION: deletion of 1 nt in FR1-IMGT
6. STOP-CODON in L-PART1, STOP-CODON in V-REGION: position 17, frameshift in V-REGION: deletion of 1 nt in FR3-IMGT, no V-NONAMER
7. no INIT-CODON: Leu instead of Met, STOP-CODON in L-PART1, STOP-CODON in L-PART2, frameshift in V-REGION: deletion of 1 nt in FR2-IMGT, no V-RS
8. no L-PART1, no L-PART2, frameshift in V-REGION: deletion of 13 nt in FR3-IMGT
9. STOP-CODON in L-PART1, frameshifts in V-REGION: several insertions and deletions, no V-HEPTAMER
10. frameshift in V-REGION: deletion of 5 nt in FR2-IMGT
11. STOP-CODON in L-PART1, frameshift in V-REGION: deletion of 1 nt in FR1-IMGT
12. frameshift in V-REGION: deletion of 1 nt in FR3-IMGT
13. frameshift in L-PART1: deletion of 1 nt causing defectuous DONOR-SPLICE, frameshift in V-REGION: deletion of 1 nt in FR1-IMGT
14. frameshift in L-PART1: deletion of 1 nt causing defectuous DONOR-SPLICE, STOP-CODON in V-REGION: position 75
15. noncanonical V-NONAMER: accccaact instead of acaaaaacc, however this X-GENE has been found rearranged
16. no L-PART1, frameshifts in V-REGION: several insertions and deletions
17. no L-PART1, no L-PART2, frameshift in V-REGION: deletion of 1 nt in FR2-IMGT
18. STOP-CODON in V-REGION: position 69
19. no 1st-CYS: Tyr instead of Cys, no CONSERVED-TRP: Cys instead of Trp, no 2nd-CYS: Ser instead of Cys
20. no L-PART1, no L-PART2, frameshifts in V-REGION: several insertions and deletions
21. noncanonical DONOR-SPLICE: ngc instead of ngt
22. noncanonical V-HEPTAMER: cacgctg instead of cacagtg, however this X-GENE has been found rearranged
23. no L-PART1, no L-PART2, STOP-CODON in V-REGION: position 7, frameshift in V-REGION: deletion of 1 nt in FR2-IMGT
24. STOP-CODON in V-REGION: position 95
25. frameshift in L-PART1: deletion of 1 nt causing defectuous DONOR-SPLICE, frameshift in V-REGION: deletion of 4 nt in FR3-IMGT
26. STOP-CODON in L-PART1, no L-PART2, no V-NONAMER
27. no L-PART1, no L-PART2, truncated pseudogene
28. several STOP-CODON in V-REGION
29. no L-PART1, STOP-CODON in L-PART2, frameshifts in V-REGION: several insertions and deletions
30. STOP-CODON in V-REGION: position 75
31. frameshift in L-PART1: deletion of 8 nt causing defectuous DONOR-SPLICE, STOP-CODON in V-REGION: position 75
32. no L-PART1, no L-PART2, frameshifts in V-REGION: several insertions and deletions, no V-NONAMER
33. no INIT-CODON: Thr instead of Met, frameshift in V-REGION: deletion of 1 nt in FR3-IMGT
34. no INIT-CODON: Thr instead of Met, STOP-CODON in L-PART1, frameshifts in V-REGION: several insertions and deletions
35. frameshift in L-PART1: deletion of 1 nt causing defectuous DONOR-SPLICE, frameshifts in V-REGION: several insertions and deletions
36. no INIT-CODON: Arg instead of Met, frameshift in V-REGION: deletion of 4 nt in FR3-IMGT
37. no L-PART2, no 1st-CYS: STOP-CODON instead of Cys, no CONSERVED-TRP: STOP-CODON instead of Trp, several STOP-CODON in V-REGION, frameshift in V-REGION: deletion of 4 nt in FR3-IMGT
38. STOP-CODON at position 116 (last 3' codon of germline V-REGION) may disappear during rearrangements
39. no INIT-CODON: Thr instead of Met, frameshifts in V-REGION: insertion of 22 nt and deletion of 1 nt in FR2-IMGT
40. STOP-CODON at position 116 (last 3' codon of germline V-REGION) may disappear during rearrangements, noncanonical V-NONAMER: gataaaacc instead of acaaaaacc, however this X-GENE has been found rearranged
41. STOP-CODON at position 116 (last 3' codon of germline V-REGION) may disappear during rearrangements, noncanonical V-NONAMER:gcctaaacc instead of acaaaaacc, however this X-GENE has been found rearranged
42. noncanonical DONOR-SPLICE: nga instead of ngt, STOP-CODON at position 116 (last 3' codon of germline V-REGION) may disappear during rearrangements, noncanonical V-NONAMER: gttaaaacc instead of acaaaaacc
43. no CONSERVED-TRP: STOP-CODON instead of Trp, several STOP-CODON in V-REGION, no 2nd-CYS: STOP-CODON instead of Cys, no V-RS
44. frameshift in L-PART1: deletion of 2 nt causing defectuous DONOR-SPLICE, STOP-CODON in V-REGION: position 95
45. frameshift in V-REGION: insertion of 1 nt in CDR2-IMGT
46. no INIT-CODON: Trp instead of Met, no DONOR-SPLICE, STOP-CODON in V-REGION: position 6, frameshift in V-REGION: deletion of 5 nt in CDR1-IMGT
47. no INIT-CODON: Val instead of Met, no DONOR-SPLICE, STOP-CODON in V-REGION: position 75
48. frameshift in L-PART1: insertion of 1 nt causing defectuous DONOR-SPLICE, several STOP-CODON in V-REGION, frameshifts in V-REGION: deletion of 8 nt and deletion of 1 nt in FR3-IMGT
49. STOP-CODON in L-PART1, truncated pseudogene, no V-NONAMER
50. no INIT-CODON: Ile instead of Met, STOP-CODON in V-REGION: position 1, frameshift in V-REGION: deletion of 2 nt in FR1-IMGT
51. noncanonical V-HEPTAMER: tacaatg instead of cacagtg
52. no L-PART1, no L-PART2, no 2nd-CYS: STOP-CODON instead of Cys, no V-RS
53. STOP-CODON in L-PART1, frameshifts in V-REGION: several insertions and deletions
54. STOP-CODON in L-PART1, no DONOR-SPLICE, frameshifts in V-REGION: several insertions and deletions
55. STOP-CODON in V-REGION: position 97
56. frameshift in V-REGION: deletion of 2 nt in FR1-IMGT
57. no L-PART1, frameshift in V-REGION: deletion of 7 nt in CDR1-IMGT
58. frameshifts in V-REGION: several insertions and deletions
59. frameshift in L-PART1: deletion of 2 nt causing defectuous DONOR-SPLICE, STOP-CODON in V-REGION: position 47
60. frameshift in L-PART1: deletion of 5 nt causing defectuous DONOR-SPLICE, frameshift in V-REGION: deletion of 1 nt in FR1-IMGT
61. STOP-CODON in V-REGION: position 51
62. frameshift in V-REGION: insertion of 2 nt in FR3-IMGT
63. no L-PART1, no L-PART2, no 2nd-CYS: STOP-CODON instead of Cys
64. no L-PART1, frameshift in L-PART2: deletion of 1 nt, frameshift in V-REGION: deletion of 1 nt in FR3-IMGT, no V-RS
65. frameshift in L-PART1: insertion of 2 nt causing defectuous DONOR-SPLICE, frameshift in L-PART2, STOP-CODON in V-REGION: position 55, frameshift in V-REGION: insertion of 1 nt in FR3-IMGT
66. frameshift in L-PART1: deletion of 1 nt and deletion of 1 nt causing defectuous DONOR-SPLICE, degenerated pseudogene, no V-RS
67. noncanonical V-NONAMER: accagaatc instead of acaaaaacc
68. STOP-CODON in V-REGION: position 38
69. STOP-CODON in L-PART1, frameshift in L-PART2: deletion of 1 nt, no CONSERVED-TRP: STOP-CODON instead of Trp
70. no L-PART1, several STOP-CODON in V-REGION, no CONSERVED-TRP: STOP-CODON instead of Trp
71. frameshift in V-REGION: deletion of 7 nt in FR3-IMGT

IMGT references: ↑

1. Manso T. et al., IMGT(R) databases, related tools and web resources through three main axes of research and development, Nucleic Acids Res, vol. 50, no. D1, 2022, pp. 1262-1272.