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IG major loci: Human

There are 3 major loci for the immunoglobulin (IG) genes and 12 IG chromosomal orphon sets [1].

IMGT major loci and links with HGNC, NCBI Gene and OMIM

IMGT locus name IMGT locus definition Chromosomal localization HGNC NCBI Gene OMIM
IGH locus Immunoglobulin heavy locus 14q32.33 IGH 3492 -
IGK locus Immunoglobulin kappa locus 2p11.2 IGK 50802 -
IGL locus Immunoglobulin lambda locus 22q11.2 IGL 3535 -

Portail to gene content in Gene tables

Genes of the human IG loci belong to ten groups:

Number of genes per locus

IMGT Posters

Questions and answers (IMGT Education)

IMGT reference:
[1] Lefranc, M.-P. and Lefranc, G., The Immunoglobulin FactsBook, Academic Press, 458 pages (2001) ISBN:012441351X.
See also:
Last updated:
Friday, 22-Sep-2023 18:21:23 CEST
Véronique Giudicelli and Marie-Paule Lefranc
Elodie Foulquier, Chantal Ginestoux