IMGT Repertoire (IG and TR) 1. Locus and genes

There are 4 major loci for the T cell receptor (TR) genes and 1 TR chromosomal orphon set [1].

IMGT major loci and links with HGNC, NCBI Gene and OMIM

IMGT locus name	IMGT locus definition	Chromosomal localization	HGNC	NCBI Gene	OMIM
TRA locus	T cell receptor alpha locus	14q11.2	TRA	6955	186880
TRB locus	T cell receptor beta locus	7q34	TRB	6957	186930
TRG locus	T cell receptor gamma locus	7p14	TRG	6965	186970
TRD locus	T cell receptor delta locus	14q11.2	TRD	6964	186810

Genes of the human TR loci belong to fourteen groups

The human TRA locus at 14q11.2 comprises genes belonging to three groups: TRAV, TRAJ and TRAC [1].
The human TRB locus at 7q34 comprises genes belonging to four groups: TRBV, TRBD, TRBJ and TRBC [1].
The human TRG locus at 7p14 comprises genes belonging to three groups: TRGV, TRGJ and TRGC [1].
The human TRD locus at 14q11.2 comprises genes belonging to four groups: TRDV, TRDD, TRDJ and TRDC [1].

IMGT Reference:
[1] Lefranc, M.-P. and Lefranc, G., The T cell receptor FactsBook, Academic Press, 398 pages (2001) ISBN:0124413528.

See also (IMGT Index):