Domestic cat (Felis catus) IGH locus on chromosome B3
- The domestic cat (Felis catus) IGH locus is on
chromosome B3. The orientation of the locus is reverse (REV).
- The domestic cat (Felis catus) IGH locus spans 2110 kilobases (kb),
from 10 kb upstream of the most 5' gene in the locus, IGHV3-89 (P), to 10 kb
downstream of the most 3' gene in the locus, IGHA (F).
The Locus representation
encompasses 2110 kb.
- The domestic cat (Felis catus) IGH locus consists
of 89 IGHV genes belonging to 4 IGHV subgroups, 6 IGHD genes belonging to 6 IGHD sets, 6 IGHJ genes belonging to 6 IGHJ sets, and
7 IGHC genes.
- The IGHV genes span 1930 kilobases (kb), the IGHD genes span 32 kilobases (kb), the IGHJ genes span 6 kilobases (kb) and
the IGHC genes span 142 kilobases (kb).
Clusters
- The IGHV genes are localized in 1 V-CLUSTER:
- The V-CLUSTER, in 5' of the IGHD, IGHJ and
IGHC, includes 89 TRBV genes belonging to 4 subgroups (36 functional, 15 ORF and 38 pseudogenes).
- The IGHD, IGHJ and IGHC genes are localized in 1
D-J-C-CLUSTER:
-
The D-J-C-CLUSTER in 3' of the IGHV includes 6 IGHD gene (4 functional and 2 ORF), 6 IGHJ genes (4 functional and 2 ORF) and 7 IGHC
gene (4 functional and 3 pseudogenes). The most C-proximal IGHJ gene, IGHJ6,
being localized at 3.454 kilobases in 5' of IGHM.
Bornes of the domestic cat (Felis catus) IGH locus on chromosome 2
- TMEM121 (3' borne) has been identified 27 kb downstream of IGHA, the most 3' gene in the locus.
- Created:
- 11/05/2026
- Last updated:
- 20/08/2026 18:08
- Author:
- Noé Mathieux
