Domestic cat (Felis catus) TRD locus
- The domestic cat (Felis catus) TRD locus is on chromosome B3.
The orientation of the locus is forward (FWD).
- The domestic cat (Felis catus) TRA/TRD locus spans 829 kilobases (kb),
from 10 kb upstream of the most 5' gene in the locus, TRAV2 (ORF), to 10 kb downstream of the most 3' gene in the locus, TRAC (F).
The Locus representation encompasses 950 kb including the 5' borne OR10G3 and the 3' borne DAD1.
- The domestic cat (Felis catus) TRD locus consists of 10 TRDV genes
belonging to 5 TRDV subgroups, 2 TRDD genes, 5 TRDJ genes and a unique TRDC gene.
- TRDV genes span 162 kilobases (kb), the TRDD genes span 26 kilobases (kb), the
TRDJ genes span 12 kilobases (kb) and the TRDC gene spans 7 kilobases (kb).
Clusters
- The TRDV genes are localized in 2 V-CLUSTER:
- the 5' V-CLUSTER, classically in 5' of the TRDD, TRDJ and
TRDC, includes 9 TRDV genes belonging to 4 subgroups.
- the 3' V-CLUSTER, downstream of the TRDC in inverted
orientation, includes 1 TRDV gene.
- The TRDD, TRDJ and TRDC genes are localized in one
D-J-C-CLUSTER between the 5' V-CLUSTER and the 3' V-CLUSTER:
- The CLUSTER includes 2 TRDD, 5 TRDJ and 1 TRDC functional .
Bornes of the domestic cat (Felis catus) TRA/TRD locus
- OR10G3 (5' borne) has been identified 116 kb upstream of TRAV2, the most 5' gene in the locus.
- DAD1 (3' borne) has been identified 13 kb downstream of TRAC, the most 3' gene in the locus.
- Created:
- 05/06/2019
- Last updated:
- Friday, 22-Sep-2023 18:22:16 CEST
- Author:
- Viviane Nguefack Ngoune and Marie-Paule Lefranc
- Editor:
- Viviane Nguefack Ngoune and Marie-Paule Lefranc
