Mouse (Mus musculus) TRD locus
- The mouse (Mus musculus) TRA locus is on chromosome 14.
The orientation of the locus is forward (FWD).
- The mouse (Mus musculus) TRA/TRD locus spans 1838 kilobases (kb),
from 10 kb upstream of the most 5' gene in the locus, TRAV1 (F), to 10 kb
downstream of the most 3' gene in the locus, TRAC (F).
The Locus representation
encompasses 2100 kb without bornes.
- The mouse (Mus musculus) TRD locus consists of 6
TRAV genes belonging to 5 TRDV subgroups, 2 TRDJ segments, 2 TRAJ segments
and 1 TRDC gene.
- The TRAV/DV genes span 1695
kilobases (kb), the TRDD genes span 9 kilobases (kb),
the TRDJ genes span 17
kilobases (kb), the TRDC genes span 7
kilobases (kb)
Clusters
- The TRDV genes are localized in 2 V-CLUSTER:
- the 5' V-CLUSTER, classically in 5' of the TRDD, TRDJ and
TRDC, includes 4 TRDV genes belonging to 4 subgroups (3 genes
are functional, and 1 gene are pseudogene).
- the 3' V-CLUSTER, downstream of the TRDC in inverted
orientation, includes 1 TRDV gene (functional).
- The TRDD, TRDJ and TRDC genes are localized in one
D-J-C-CLUSTER between the 5' V-CLUSTER and the 3' V-CLUSTER:
- The CLUSTER includes 2 TRDD genes belonging to 2
subgroups functional, 2 TRDJ (2 genes are functional) and 1 TRDC functional .
More information:
Gene table: Mouse (Mus musculus) TRDV
Gene table: Mouse (Mus musculus) TRDD
Gene table: Mouse (Mus musculus) TRDJ
Gene table: Mouse (Mus musculus) TRDC
Potential germline repertoire: Mouse (Mus musculus) TRDV genes
Locus description: Mouse (Mus musculus) TRD
See also:
Genomic orientation (IMGT Index)
Taxonomy: Eutheria
