IMGT Repertoire (IG and TR)

Chromosomal localization: human (Homo sapiens) TRB

The human (Homo sapiens) TRB locus is located on chromosome 7 [1-4], on the long arm, at band 7q34 [5].

The orientation of the human TRB locus on the chromosome is forward (FWD).
The orientation of the locus has been determined by the analysis of translocations, involving the TRB locus, in leukemia and lymphoma.

A vertical red line indicates the localization of the TRB locus at 7q34.
A blue arrow indicates the orientation 5' → of the locus, and the gene group order in the locus. Note that the TRBV gene localized at the 3' end of the TRB locus is in inverted orientation of transcription (shown by a small black arrow). The blue arrow is proportional to the size of the locus, indicated in kilobases (kb). The total number of genes in the locus is shown between parentheses.

Chromosomal localization human TRB

IMGT references:
  1. [1] Collins, M.K.L. et al., EMBO J., 3, 2347-2349 (1984).
  2. [2] Barker, P.E. et al., Science, 226, 348-349 (1984).
  3. [3] Caccia, N. et al., Cell, 37, 1091-1099 (1984).
  4. [4] Isobe, M. et al., Science, 228, 580-582 (1985).
  5. [5] Reynolds, T.C. et al.? Cell, 50, 107-117 (1987).
See also:
Last updated:
Chantal Ginestoux and Marie-Paule Lefranc