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"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

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Click here for Number of genes as deduced by RFLP analysis.

IMGT gene name IMGT allele name Fct Chromosomal localization T Pr Positions in the locus IMGT/LIGM-DB reference sequences IMGT/LIGM-DB sequences from the literature
Strain Clone names Exons Accession numbers Positions in the sequence (C-REGION) Secondary accession numbers Strain Clone names Accession numbers Positions in the sequence (C-REGION)
IGLC1 (1)
IGLC2 IGLC2*01 F SPE Clambda2SPE MAP M16554 [1]
IGLC2*02 F B6.lambdaSEG Clambda2SEG MAP AF357973 [2]
IGLC3 (1)
IGLC4 IGLC4*01 P (2) SPE Clambda4S (Clambda4SPE) MAP M16628 [1]
IGLC4*02 P (2) B6.lambdaSEG Clambda4SEG1 MAP AF357972 [2]
IGLC5 IGLC5*01 F (3) B6.lambdaSEG Clambda4SEG2 MAP AF357974 [2]

MAP: Mapped reference sequences.

IMGT notes:
  1. (1) The cluster IGLV1-IGLJ3-IGLC3-IGLJ1-IGLC1 is deleted in B6.lambdaSEG and probably also in the lost strain SPE [2].
  2. (2) Several DELETIONS leading to frameshifts and STOP-CODONS.
  3. (3) IGLC5 is preceded by IGLJ5 which is an ORF.
IMGT references:
  1. [1] Mami F. and Kindt T.J., J. Immunol., 138, 3980-3985 (1987). PMID:2820875
  2. [2] Amrani Y.M. et al., Immunogenetics, 54, 106-119 (2002). PMID:12037603
Last updated:
Dominique Scaviner, Delphine Guiraudou