IMGT Repertoire (IG and TR)

Fct: FUNCTIONALITY
- F: Functional
- P: Pseudogene
- ORF: Open Reading Frame
T: Transcribed
Pr: Translated into protein

"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

Click on:

IMGT gene name to get the corresponding IMGT/GENE-DB entry,
IMGT allele name to see the corresponding Alignments of alleles,
accession number to get the corresponding IMGT/LIGM-DB entry.

IMGT gene name	IMGT allele name	Fct	T	Pr	Positions in the locus	IMGT/LIGM-DB reference sequences						IMGT/LIGM-DB sequences from the literature
IMGT gene name	IMGT allele name	Fct	T	Pr	Positions in the locus	Strain	Clone names	Exons	Accession numbers	Positions in the sequence (exons)	Secondary accession numbers	Strain				Clone names	Accession numbers	Positions in the sequence (exons)
	IGHT	IGHT*01	F								CH1	AY872256	[1]			32069-32365
											CH2	AY872256	[1]			32572-32856
											CH3	AY872256	[1]			32981-33298
											CH4	AY872256	[1]			33620-33957
											M1	AY872256	[1]			34749-34903
											M2	AY872256	[1]			35243-35251
	IGHM1	IGHM1*01	F								CH1	AY872256	[1]			93022-93318
											CH2	AY872256	[1]			94474-94815
											CH3	AY872256	[1]			95119-95418
											CH4	AY872256	[1]			95827-96227
											M1	AY872256	[1]			98574-98710
											M2	AY872256	[1]			99573-99578
		IGHM1*02	(F)			+	+			lambda RT15	CH1	X65262	[2]	(1)	#c(s)	382-519			lambda RTHC1	X67713	[2]	(1)
											CH1	X65261	[2]	(2)	#c(s)	1-162			lambda RTHC1	X67713	[2]	(1)
											CH2	X65261	[2]		#c(s)	163-504			lambda RTtm	X65263	[2]	(3)	#c(m)
											CH3	X65261	[2]	(4)	#c(s)	505-804			lambda RTtm	X65263	[2]		#c(m)
											CH4	X65261	[2]	(4)	#c(s)	805-1206
										lambda RTtm	M1	X65263	[2]	(4)	#c(m)	356-493
										lambda RTtm	M2	X65263	[2]		#c(m)	494-499
		IGHM1*03	(F)			+	+			cRTVH50	CH1	S63348	[3]		#c(s)	403-699			cRTVH50/CH	Y08598	[4]		#c(s)
											CH2	S63348	[3]		#c(s)	700-1041			cRTVH50/CH	Y08598	[4]		#c(s)
											CH3	S63348	[3]	(4)	#c(s)	1042-1341			cRTVH50/CH	Y08598	[4]		#c(s)
											CH4	S63348	[3]	(4)	#c(s)	1342-1743			cRTVH50/CH	Y08598	[4]		#c(s)
		IGHM1*04	(F)			+	+			RBTIGTM2	CH1	U04615	[5]		#c(m)	403-699
											CH2	U04615	[5]		#c(m)	700-1041
											CH3	U04615	[5]	(4)	#c(m)	1042-1344
											M1	U04615	[5]	(4)	#c(m)	1345-1482
											M2	U04615	[5]		#c(m)	1483-1488
		IGHM1*05	(F)			+	+			RBTIGTM1	CH1	U04616	[5]		#c(m)	406-702
											CH2	U04616	[5]		#c(m)	703-1044
											CH3	U04616	[5]	(4)	#c(m)	1045-1347
											M1	U04616	[5]	(4)	#c(m)	1348-1485
											M2	U04616	[5]		#c(m)	1486-1491
	IGHM2	IGHM2*01	F							gRTIgM	CH1	X83372	[6]	(2)		1-271
											CH2	X83372	[6]			1429-1770
											CH3	X83372	[6]			2074-2373
											CH4	X83372	[6]	(5)		2785-3071
	IGHD	IGHD*01	F								CH1	AY872256	[1]			100661-100999
											CH2	AY872256	[1]			101125-101424
											CH3	AY872256	[1]			104153-104467
											CH4	AY872256	[1]			104627-104920
											CH2D	AY872256	[1]			105057-105356
											CH3D	AY872257	[1]			844-1158
											CH4D	AY872257	[1]			1318-1611
											CH2D2	AY872257	[1]	(6)		1748-2047
											CH7	AY872257	[1]			6737-7024
											M1	AY872257	[1]			7191-7342
											M2	AY872257	[1]			7739-7744

#c: rearranged cDNA.
(s) Trancript of a secreted chain.
(m) Trancript of a membrane chain.

IMGT notes:

(1) Functional but the C-REGION is partial in 3': CH1 is partial
(2) Functional but the C-REGION is partial in 5': CH1 is partial
(3) Functional but the C-REGION is partial in 5': CH2 is partial
(4) Functional but CH3 is spliced to CH4 in secretory mu cDNA, whereas it is spliced to the M1 exon in membrane mu cDNA (see [2]).
(5) Functional but the C-REGION is partial in 3': CH4 is partial
(6) Functional but the C-REGION contains repetitive regions

IMGT references:

[1] Hansen J.D. et al., Proc. Natl. Acad. Sci. U.S.A., 102, 6919-6924 (2005). PMID:15863615
[2] Lee M.A. et al., Mol. Immunol., 30, 641-648 (1993). PMID:8487781
[3] Andersson E. and Matsunaga T., Immunogenetics, 38, 243-250 (1993). PMID:8319974
[4] Andersson E. et al., Unpublished (1996).
[5] Hansen J. et al., Mol. Immunol., 31, 499-501 (1994). PMID:8183286
[6] Andersson E. et al., Immunogenetics, 41, 312-315 (1995). PMID:7721353
[7] Roman T. et al., Immunogenetics 43, 325-326 (1996). PMID:9110939

See also (IMGT Scientific chart):

Created:: 15/12/2009
Last updated:: 22/09/2023
Authors:: Sylvaine Artero, Nathalie Bosc, Géraldine Folch, Amandine Lacan

IMGT Repertoire (IG and TR)

Gene table: rainbow trout (Oncorhynchus mykiss) IGHC