IMGT Repertoire (IG and TR)

Fct: FUNCTIONALITY
- F: Functional
- P: Pseudogene
- ORF: Open Reading Frame
T: Transcribed
Pr: Translated into protein

"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

Click on:

IMGT gene name to get the corresponding IMGT/GENE-DB entry,
IMGT allele name to see the corresponding Alignments of alleles,
accession number to get the corresponding IMGT/LIGM-DB entry.

IMGT gene name	IMGT allele name		Fct	T	Pr	Positions in the locus	IMGT/LIGM-DB reference sequences							IMGT/LIGM-DB sequences from the literature
IMGT gene name	IMGT allele name		Fct	T	Pr	Positions in the locus	Strain	Clone names	Exons	Accession numbers	Positions in the sequence	Secondary accession numbers		Strain	Clone names	Accession numbers			Positions in the sequence
	IGHG1	(1)	IGHG1*01	(F)								CH1				AJ421266		c
												H				AJ421266		c
												CH2				AJ421266		c
												CH3 (including CHS)				AJ421266		c
												M1
												M2
	IGHG2	(2)	IGHG2*01	F							ch51666	CH1	(2)			AJ131945	(3)
												H				AJ131945
												CH2				AJ131945
												CH3 (including CHS)				AJ131945
												M1				AJ131945
												M2				AJ131945
	IGHG3	(2)	IGHG3*01	(F)								CH1	(2)
												H				Z48947		c (s)
												CH2				Z48947		c (s)
												CH3 (including CHS)				Z48947		c (s)

c: cDNA sequence.
(s) Transcript of a secreted chain.

IMGT notes:

(1) The IGHG1 gene encodes a classical gamma 1 chain, part of a conventional tetrameric IgG1.
(2) The IGHG2 gene and IGHG3 gene encode a gamma 2 chain and a gamma 3 chain, respectively, which are both characterized by the absence of the CH1 domain due to a splicing defect of the CH1 exon.
(3) IGHV genes expressed with the gamma2 and gamma3 chains comprise genes belonging to the IGHV1 second set (see Germline gene table).

IMGT references:

[1] Nguyen V.K. et al., Mol. Immunol., 36, 515-524 (1999). PMID:10475606
[2] Atarhouch T. et al., Unpublished.
[3] Nguyen V.K. et al., Immunogenetics, 54, 39-47 (2002). PMID:11976790

See also (IMGT Scientific chart):

Created:: 22/11/2001
Last updated:: 22/09/2023
Authors:: Christèle Martinez-Jean, Joumana Jabado-Michaloud

IMGT Repertoire (IG and TR)

Gene table: arabian camel (Camelus dromedarius) IGHC