IMGT Repertoire (IG and TR)

Gene table: human (Homo sapiens) IGKC

"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

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IMGT gene name IMGT allele name Fct Chromosomal localization T Pr Allotypes Isoallotypes Positions in the locus IMGT/LIGM-DB reference sequences IMGT/LIGM-DB sequences from the literature
Clone names Exons Accession numbers Positions in the sequence Secondary accession numbers Clone names Accession numbers Positions in the sequence
IGKC IGKC*01 F 2p11.2 Km3 Inv3 J00241 [1] X67858 [3]
U72063 [4]
X96754 [7]
IGKC*02 F 2p11.2 Km3 geV-4 M11736 [2]
IGKC*03 F 2p11.2 Km3 geV-3 M11737 [2]
IGKC*04 F 2p11.2 Km1,2 AF017732 [6]
IGKC*05 (F) 2p11.2 Km3 AF113887 [5] (1) c

c: cDNA sequence.

IMGT notes:
  1. (1) The IGKC*05 allele was found expressed in the Bence Jones protein BIF and the amyloid protein BIF [8].
IMGT references:
  1. [1] Hieter P.A. et al., Cell, 22, 197-207 (1980). PMID:6775818
  2. [2] Stavnezer-Nordgren J. et al., Science, 230, 458-461 (1985). PMID:3931219
  3. [3] Whitehurst C. et al., Nucleic Acids Res., 20, 4929-4930 (1992). PMID:1408808
  4. [4] Hu W.X. et al., Sheng Wu Hua Hsueh Yu Sheng Wu Wu Li Hsueh Pao, 27, 215-221 (1995).
  5. [5] Wally J. et al., Biochim. Biophys. Acta, 1454, 49-56 (1999). PMID:10354514
  6. [6] Brandt P. et al., Unpublished.
  7. [7] Hilger C. et al., Unpublished.
  8. [8] Solomon A. et al., Proc. Natl. Acad. Sci. USA, 95, 9547-9551 (1998). PMID:9689117
Last updated:
Christèle Martinez-Jean