Here you are: IMGT Web resources > IMGTrepertoire (RPI) > 1. Locus and genes

Homo sapiens VPREB and IGLL genes on chromosome 2 (22q11.21-22q11.23)

Homo sapiens VPREB and IGLL genes and chromosomal localizations

Gene name Chromosomal location NC positions (1) Orientation Gene definition and aliases Funct HGNC UniProt Gene ID OMIM IMGT/3Dstructure-DB
IGLL1 22q11.23 NC_000022.11 (23573125..23580548, complement) REV immunoglobulin lambda-like 1, 14.1, CD179b F IGLL1 P15814 3543 146770 2h32, 2h3n
IGLL2 22q11.23 -2 immunoglobulin lambda-like 2 pseudogene,16.2, FLAMBDA1, ILL2P P IGLL2P 3544
IGLL3 22q11.23 NC_000022.11 (25318257..25320227) FWD immunoglobulin lambda-like 3, 16.1 F IGLL3P (3) 91353
IGLL4 22q11.21 NC_000022.11 (20632590..20632826) FWD immunoglobulin lambda-like 4 pseudogene P IGLL4P 100287528
IGLL5 22q11.22 NC_000022.11 (22887780..22895834) FWD immunoglobulin lambda-like 5 F IGLL5 B9A064 100423062
VPREB1 22q11.2 NC_000022.11 (22244780..22245515) FWD pre-B lymphocyte 1, VpreB, CD179a F VPREB1 P12018 7441 605141 2h32, 2h3n, 3bj9
VPREB3 22q11.23 NC_000022.11 (23752743..23754443, complement) REV pre-B lymphocyte 3 F VPREB3 Q9UKI3 29802 605017
Other genes
IGLJ1 22q11.2 NC_000022.11 (22893781..22893818) FWD immunoglobulin lambda joining 1 F IGLJ1 28833
IGLC1 22q11.2 NC_000022.11 (22895375..22895694) FWD immunoglobulin lambda constant 1 (Mcg marker) F IGLC1 P0CG04 3537 147220
IGLC7 22q11.2 NC_000022.11 (22922594..22922913) FWD immunoglobulin lambda constant 7 F IGLC7 A0M8Q6 28834
GUSBP11 22q11.23 NC_000022.11 (23638487..23717423, complement) REV glucuronidase, beta pseudogene 11 P GUSBP11 Q6P575 91316

IMGT Note: (1) GRCh38.p7 (2) not present in GRCh38.p7 (3) IGLL3 is functional according to IMGT.

⇑ Top

Representation of the Homo sapiens VPREB and IGLL genes on chromosomes

Arrows show genes with a reverse (REV) orientation on the chromosome (IMGT Index > Genomic orientation)

The Homo sapiens IGL locus (22q11.2) which spans 1,050 kb is represented by a horizontal arrow. Its orientation on the chromosome is forward (FWD).
Only the IGLJ1 and IGLC1 genes which encompass the IGLL5 gene are shown. For a representation of the IGL locus , see Human (Homo sapiens) IGL locus on chromosome 22(22q11.2)
Arrows show the genes whose orientation is reverse (REV) on the chromosome.

⇑ Top

Legend:

More information:

Human (Homo sapiens) IGL locus on chromosome 22 (22q11.2)


Created:
30/11/2015
Last updated:
Friday, 22-Sep-2023 18:32:04 CEST
Authors:
Mélissa Cambon, Souphatta Sasorith and Marie-Paule Lefranc
Contact:
Marie-Paule Lefranc