IMGT Repertoire (RPI)

____________________________________________________________________________________________________________________________________________________________________________________________________________________________

 Accession     Gene   Species
  number       name
____________________________________________________________________________________________________________________________________________________________________________________________________________________________
                                                          L-REGION                    A        AB     B           BC         C     CD      D          DE           E      EF   F                FG                 G
                                                                                    (1-15)          (16-26)    (27-38)    (39-45)       (77-84)                 (85-96)     (97-104)         (105-117)         (118-128)
                                                  —————————————————————————>    ——————————————>   ——————————>             ——————>       ———————>              ———————————>  ———————>                           ——————————>
                                                                                1        10  15   16  20 2326 27      38  3941 45       77 80 84              85  89    96  97   104 105 111          112  117 118     128
                                                                            321 |........|....|123|...|..|..| |........|  |.|...|1234567|..|...|12345677654321|...|......|12|......| |.....|123456654321|....| |.........|
AB021288	B2M   Homo sapiens  c		        MSRSVALAVLALLSLSGLEAIQR TPKIQVYSRHPAEN....GKSNFLNCYVS GFHP..SDIE  VDLLKNGERIE...KVEHSDLSFSKD......WSFYLLYYTEFTP.....TEKDEYAC RVNHVT..............LSQPK IVKWDRDM
AL845457	B2M   Mus musculus		        MARSVTLVFLVLVSLTGLYAIQK TPQIQVYSRHPPEN....GKPNILNCYVT QFHP..PHIE  IQMLKNGKKIP...KVEMSDMSFSKD......WSFYILAHTEFTP.....TETDTYAC RVKHAS..............MAEPK TVYWDRDM
Y00441  	B2M   Rattus norvegicus  c              MARSVTVIFLVLVSLAVVLAIQK TPQIQVYSRHPPEN....GKPNFLNCYVS QFHP..PQIE  IELLKNGKKIP...NIEHSDMSFSKD......WSFYILAHTEFTP.....TETDVYAC RVKHVT..............LKEPK TVTWDRDM
X69084  	B2M   Bos taurus  c                     MARFVALVLLGLLSLSGLDAIQR PPKIQVYSRHPPED....GKPNYLNCYVY GFHP..PQIE  IDLLKNGEKI....KSEQSDLSFSKD......WSFYLLSHAEFTP.....NSKDQYSC RVKHVT..............LEQPR IVKWDRDL
DN889857  	B2M   Oryctolagus cuniculus  c	       MSRSVLGLALLALVLFPCLECVQR APNVQVYSRHPAEN....GKPNFLNCYVS GFHP..PQID  IELLKNGVKIE...NVEQSDLSFNKD......WSFYLLVHTEFTP.....NDKDEYSC RVKHVT..............LKEPM TVKWDRDY
AF148875  	B2M   Cavia porcellus  c	  MARSVALVSLALLAVLALLSLPAVDAVLH APRVQVYSRHPAEN....GKQNFINCYVS GFHP..PQIE  VELLKNGKKID...NVEMSDLSFSKD......WTFYLLVHAAFTP.....NDSDEYSC RVSHIT..............LSEPK IVKWDPNK
M84767  	B2M   Gallus gallus  c		        MGKAAAVVLVTLVALLGLAQADL TPKVQVYSRFPASA....GTKNVLNCFAA GFHP..PKIS  ITLMKDGVPME...GAQYSDMSFNDD......WTFQRLVHADFTP.....SSGSTYAC KVEHET..............LKEPQ VYKWDPEF
P21612  	B2M   Meleagris gallopavo	                             DL TPKVQVYSRFPASA....GTKNVLNCFAA GFHP..PKIS  ITLMKDGVPME...GAQYSDMSFNDD......WSFQRLVYADFTP.....SSDAVYTC KVDHET..............LKEPQ VYKWDPEF
BQ389924  	B2M   Xenopus tropicalis  c	       MKIALSLLSLGLVLALTLAESNIS PPVVKVYTAEPVEF....GKKNELICYAY DYHP..PRME  ISLLKNGVEIP...DTKQKDPSFHHN......WKYYTMMSAHVHI.....DSDDKVEC LVAHN...............GSPPK RHKLDMFA
AF217962  	B2M   Xenopus laevis  c		       MKIALVLLSL...LALTLAESNIS PPVVKVYTAEPVDF....GKTNEVICYVY NYHP..PRLE  MRLEKNGVEIP...DCKQTDPSFQHN......WKYYTTKSTHVHI.....DKGDKVEC VVSHN...............GNPSK KYRLDIFA
BG407436  	B2M   Xenopus laevis EST1  c	       MKIVLVLLSLGLSLALTWAESNIS PPVVKVYTAEPVDF....GKTNEVICYVY NYHP..PRLE  MRLEKNGVEIP...DCKQTDPSFQHN......WKYYTMKSTHVHI.....DKGDKVEC VVSHN...............GNPSK KYRLDIFA
BG814676  	B2M   Xenopus laevis EST2  c	       MKIVLVLLSLGLSLALTWAESNIS PPVVKVYTAEPVDF....GKTNEVICFLY NYHP..PLLE  MRLENNGLETP...VCKQTDPSFQHN......WKYHTM
AF433657  	B2M   Paralichthys olivaceus  c          MGLLICSLLLGLLCCSM.AKDT PPKVEVYTREPEEF....GKPNSFICHVS GFYP..PQIN  ITLLKDGKEIP...NTQQTDLAFEAN......WYYYLTKHVSFTP.....KEDDEFIC RVTHM................GKSK DHFLMIGL
AJ507010  	B2M   Barbus intermedius  c              MRAIITFALFCVLYITVQAKTS SPKVQVYSHFPGEY....GKENTLICHVS GFHP..PDIT  IELLRNGEILP...NTQQTDLAFEKG......WQFHLTKSVSFTP.....ERGQDYAC KVRHM................SNTN AYSWEPNM
AB190815  	B2M   Ctenopharyngodon idella  c         MRALVSFALFCVLYISVQGKVS SPKIQVYSHYPGEY....GKENTLICYVS GFHP..PDIS  IELLKNGEVIA...DAQQTDLAFEKG......WQFHLTKSVSFKP.....EKSDEYSC SVRHM................SKTK KIVWESNM
L05536  	B2M   Cyprinius carpio  c                MRAIITFALFCVLYVTVQGKTS SPKVQVYSHFPGEY....GKENTLICHVS GFHP..PDIT  IELLKDGEILP...NTQQTDLAFEKG......WQFHLTKSVTFKP.....ERGQNYAC SVRHM................NNKN IYSWEPNM
L05383  	B2M   Danio rerio  c                     MRALITFALLCLLYITVQGKVS TPKVHVYSHFPGEY....GKPNTLICYVS SFHP..PDIS  IELLKNGQVMS...DTKQTDLAFEKG......WQFHLTKSVAFTP.....EKGDEYTC SVRHM................KETK KFSWEPNM
AF016042  	B2M   Ictalurus punctatus                MKFLLSFVVLAVFSASAFAKES PPKIQVYSRNPGEF....GKENTLICHVS DFHP..PDIT  IDLLKNGEVIP...NAEQTDLAFEKG......WKFHLTKSVSFTP.....TSNDKFTC RVRHL................KETK NISWEPDM
L63534  	B2M   Oncorhynchus mykiss  c             MKYILSIVVLGLIYSVVEAKES PPKVQVYSRNPGNF....GDKNTLICHVS GFHP..PDIS  IQLLKNGVEIP...DAKQTDLAFEQG......WQFHLTKSVGFTP.....ASGEEYTC RVRHL................KNLK TYTWEADM
L49056  	B2M   Oncorhynchus mykiss  c             MKYILSIVVLGLIYSAVEAKES PPKVQVYSRNPGNF....GDKNTLICHVS GFHP..PDIS  IQLLKNGVEIP...DAKQTDLAFEQG......WQFHLTKSVGFTP.....ASGEEYTC RVRHL................KNLK TYTWEADM
AF180488  	B2M   Salmo salar  c                     MKTVLSVIAFCVFLGFINAKES PPKVQVYSRNPGEH....GKDNTLICHVS GFHP..PDIS  IQLLKNGVEIP...DAKQTDLAFEQG......WQFHLTKSVGFTP.....DSGEEYTC RVRHL................KNLK TYTWESNM
AJ133653  	B2M   Acipenser baeri                MFLRSTFVAALVACLAYIHLGDATEA MPKVQIYSRNVGEL....GKPNTLICHVS GFHP..PNIK  LQLLKNDVEIE...GAQQSDLAFHQG......WHFHLTKSVAFTP.....KEGEHYSC KVEHST..............LREAT RFTWTPDM
AJ132752  	B2M   Gadus morhua  c                    MKITFCTVAVALLLCTVESKES VPKVQVYSSKPAEL....GEANTLICLVQ AFHP..PEIT  IELLKDGAVLP...NANQTDLSFDKT......WHFHLSKFADITP.....SKEESYAC QVTHI................GKRT VHAWEPNM
AF520476  	B2M   Raja eglanteria  c                     MRALILLSLGLLRVAVPS PPQVVVYTYKPVVH....GEKNTLLCHAK EFNP..PNVE  LQLFEDGNVFS...QANQTDLSFESN......WKFKLTKFIELIP.....REDVEYSC HVMYM................GKTS IYKLESF

c : cDNA sequence

Legend:

Acipenser baerii (Siberian sturgeon)

Barbus intermedius (Barbus)

Bos taurus (Cow)

Cavia porcellus (Guinea pig)

Ctenopharyngodon idella (Grass carp)

Cyprinius carpio (Common carp)

Danio rerio (Zebrafish)

Gadus morhua (Atlantic cod)

Gallus gallus (Chicken)

Homo sapiens (Human)

Ictalurus punctatus (Channel catfish)

Meleagris gallopavo (Turkey)

Mus musculus (House mouse)

Paralichthys olivaceus (Bastard halibut)

Oncorhynchus mykiss (Rainbow trout)

Oryctolagus cuniculus (Rabbit)

Raja eglanteria (Clearnose skate)

Rattus norvegicus (Norway rat)

Salmo salar (Atlantic salmon)

Xenopus tropicalis (Western clawed frog)

Xenopus laevis (African clawed frog)

This protein display shows examples of C-DOMAINs (IG and TR) and C-LIKE-DOMAINs (proteins other than IG or TR).

Dots indicate gaps according to the IMGT unique numbering for C-DOMAIN and C-LIKE-DOMAIN.
Only the *01 allele of each functional, ORF and in-frame pseudogenes C-LIKE-DOMAIN is shown.
N-glycosylation sites (NXS/T, where X is different from P) are underlined.
Parentheses at the beginning of the sequence lines indicate amino acids which result from the splicing with the preceding exon. For domain 2 [D2] of FCGR3B Human, the information is from M90745. For [D2] of FCGR1, FCGR2A, FCGR2B and FCER1, the amino acid resulting from the splicing is by homology with FCGR3B.

(1)	Positions 1.3 and 1.2 are encoded by the 3' end of EX1. Position 1.1 results from the splicing between EX1 and EX2 (codon_start3).
(2)	Sequences of the C-LIKE-DOMAIN (positions 1.3 to 125) are in IMGT/DomainDisplay.

IMGT Repertoire (RPI)

Protein display Beta-2-microglobulin C-LIKE-DOMAIN (proteins other than IG or TR)