IMGT Repertoire (RPI)

Protein display of C-LIKE-DOMAIN (proteins other than IG or TR): Homo sapien IGLL

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      IGLL
      genes
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                                  1       10        20        30        40        50        60        70
                                  ....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|
  M27749  ,IGLL1  EX1             MRPGTGQGGLEAPGEPGPNLRQRWPLLLLGLAVVTHGLLRPTAASQSRALGPGAPGGSSRSSLRSRWG
  X52203  ,IGLL2  EX1  (2)        MCHSGSCWDLLGPALPSAPTASERGTYAGVTPRLWAAPASDREQAQRHYWGTLLGYWPPPCPVPGSQPTHCSPVPLTPS
  AL022324,IGLL3  EX1             MGHGETDARVRGKGSLRPQGKRVTGKRGQSHVISSRDTRYSRRTLDMTMRRALLAMTWERW





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      IGLL
      genes (1)
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                                  1    5   10   15   20   25   30   35   40
                                  . ...|....|....|....|....|....|....|....|
  M27749  ,IGLL1  EX2            (R)FLLQRGSWTGPRCWPRGFQSKHNSVTHVFGSGTQLTVL
  X52203  ,IGLL2  EX2  (2)       (R)FLLQRGSWTGARCWPWGFQSKHNSVKHVFGSGTQLTVL
  AL022324,IGLL3  EX2            (G)FLLQRGSWTGPGCWPRGFQSKHNSVKHVFGSGTQLTVL




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      IGLL
      genes
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                                                A        AB     B          BC         C     CD      D          DE           E      EF   F            FG          G
                                              (1-15)          (16-26)    (27-38)    (39-45)       (77-84)                 (85-96)     (97-104)    (105-117)  (118-128)
                                         ———————————————>   ——————————>             ——————>       ———————>              ———————————>  ———————>               ——————————>
                                         1         10  15   16  20 2326 27      36  3941 45       77 80 84              85  89    96  97   104  105      117 118     128
                                87654321 | ........|....|123|...|..|..| |........|  |.|...|1234567|..|...|12345677654321|...|......|12|......| |...........| |.........|
  M27749  ,IGLL1  EX3            (S)QPKA T PSVTLFPPSSEELQ...ANKATLVCLMN DFYP..GILT  VTWKADGTPITQ..GVEMTTPSKQSN......NKYAASSYLSLTPEQW..RSRRSYSC QVMHE....GSTV EKTVAPAECS
  X52203  ,IGLL2  EX3  (2)       (G)QPKT T PSVILFLPSCEEPQ...ANKATLVCLMN N#YP..GILM  VTWKADGTLITQ..SVEKTTPSKQSN......NKYVASSYLSLTPEQW..RSRRSYSC QVMQE....GSTV EKSVAPAECS
  AL022324,IGLL3  EX3            (G)QPKA T PSVTLFLPSSEELQ...ANKATLVCLMN DFYL..GILT  VTWKADGTPITQ..GVEMTTPSKQSN......SKYMASSYLSLTPEQW..RSRRSYSC QVMHE....GSTA EKTVAPAECS

Legend:

This protein display shows examples of C-DOMAINs (IG and TR) and C-LIKE-DOMAINs (proteins other than IG or TR).
Dots indicate gaps according to the IMGT unique numbering for C-DOMAIN and C-LIKE-DOMAIN.
N-glycosylation sites (NXS/T, where X is different from P) are underlined.
Parentheses at the beginning of the sequence lines indicate amino acids which result from the splicing with the preceding exon. For domain 2 [D2] of FCGR3B Human, the information is from M90745. For [D2] of FCGR1, FCGR2A, FCGR2B and FCER1, the amino acid resulting from the splicing is by homology with FCGR3B.
Only the EXONs of the *01 allele are shown.
Letters in red correspond to amino acids which are polymorphic in the other alleles.

IMGT notes:
(1)	The F, G and G of the FGXG motif found in J-REGIONs are shown in brown.
(2)	IGLL2 is a Pseudogene, because of one nucleotide DELETION in EX3 (codon at positon 28 according to the IMGT numbering for C-DOMAIN and C-LIKE-DOMAIN) leading to a frameshift.

See also:

IMGT Repertoire:
- Protein display: C-DOMAIN (IG and TR) and C-LIKE-DOMAIN (proteins other than IG or TR)
IMGT Scientific chart:

The protein display numbering is according to the IMGT unique numbering for for C-DOMAIN and C-LIKE-DOMAIN.
Colors are according to IMGT color menu for genes.