ORIENTATION
The 'ORIENTATION' axiom is one of the seven axioms of the Formal IMGT-ONTOLOGY or IMGT-Kaleidoscope [1-3].
The 'ORIENTATION' axiom postulates that molecules, cells, organs, organisms or populations and their processes and relations have to be orientated. The 'ORIENTATION' axiom has generated concepts of orientation, for example:
- the 'Genomic orientation' concept (for chromosome, locus and gene),
- the 'DNA strand orientation' concept.
References:
[1] Giudicelli, V. and Lefranc, M.-P., Bioinformatics, 15, 1047-1054 (1999).
PMID: 10745995,
LIGM:221
[2] Giudicelli, V. and Lefranc, M.-P.
"Le paradigme IMGT-ONTOLOGY"
In: Biologie Systémique Standards et modèles (Roux M. Ed.), Collection Ecrin, Omniscience,
Presses Universitaires de France, Paris, 2007, Chapitre 6, pp143-164. ISBN: 978-2-916097-12-1
[3] Duroux, P. et al., "IMGT-Kaleidoscope, the Formal IMGT-ONTOLOGY paradigm",
Biochimie, 90, 570-583 (2008). Epub 2007 Sep11.
PMID: 17949886