Collier de Perles: Mouse (Mus musculus) IGH V-D-J REGION from E5.2 Fv (PDB: 1dvf_D)

IMGT/3Dstructure-DB card: 1dvf

Side view (backbone model)
View from above the CDRs (backbone model)

Collier de Perles: Mouse IGK V-J REGION

Mouse rearranged IGH V-D-J2 REGION (with IMGT modification)
[8.8.15]

The PBD file 1dvf contains the atomic coordinates of the complex between Idiotope D1.3-Antiidiotope E5.2. Both D1.3 and E5.2 are mouse (Mus musculus) antibodies (IgG1, kappa). Only the IGH V-DOMAIN of E5.2 "Fv" (for "Fragment variable") (PDB: 1dvf_D) is displayed here.

IMGT modification:
IMGT unique numbering for the graphical representation of the IGH V-D-J REGION of the mouse antibody E5.2 Fv revealed a conflict between the amino acid sequence and the atomic coordinate data, in the PDB file 1dvf: Leu-Ser-Leu (SEQRES lines) and Leu-Leu-Leu (ATOM lines). The original sequence [1] is Leu-Ser-Ser-Leu (positions 91 to 94 in the IMGT unique numbering; the Serine added at position 93 is shown between parentheses).
[1] Goldbaum F.A. et al., J. Mol. Biol., 241, 739 (1994)

Legend:


Created: 19/12/1997
Last updated: Wednesday, 20-Jan-2021 08:25:00 CET
Authors: Manuel Ruiz, Elodie Foulquier and Marie-Paule Lefranc
Editors: Elodie Foulquier and Marie-Paule Lefranc