IMGT Web resources: IMGT repertoire

3D representation: Mouse (Mus musculus) V-DOMAINs from E5.2 Fv (PDB: 1dvf_C and 1dvf_D)

IMGT/3Dstructure-DB card: 1dvf

View from above the CDRs (backbone model)

Legend:

CDR-IMGT regions are colored according to the IMGT color menu:
TRA V-J-REGION: CDR1-IMGT (blue), CDR2-IMGT (green), CDR3-IMGT (greenblue)
TRB V-D-J-REGION: CDR1-IMGT (red), CDR2-IMGT (orange), CDR3-IMGT (purple)
The N (cyan) and C (magenta) ends of each region are also colored.
The conserved C 23, W 41 and L 89, and the FR-IMGT amino acids limiting the CDR-IMGT regions (positions 26 and 39 for the CDR1-IMGT, 55 and 66 for the CDR2-IMGT, 104 and 118 for the CDR3-IMGT) are shown in white.
This image has been generated with the program RASMOL version 2.6 [1] from the PDB file 1dvf [2], containing the atomic coordinates of the complex between Idiotope D1.3-Antiidiotope E5.2. Both D1.3 (PDB: 1dvf_A, 1dvf_B)and E5.2 (PDB: 1dvf_C, 1dvf_D) are mouse (Mus musculus) antibodies (IgG1, kappa). Only the IGH V-DOMAIN of E5.2 (or "Fv", for "Fragment variable") are displayed here.

References:
[1] Sayle, R. and Milner-White, E.J., TIBS, 20, 374-376 (1995).
[2] Braden, B.C. et al., J. Mol. Biol., 22, 264: 137-151 (1996).

Created: 19/12/1997
Last updated: Friday, 22-Sep-2023 18:17:04 CEST
Author: Manuel Ruiz
Editor: Elodie Foulquier