IMGT Repertoire (IG and TR)

✤ : NCBI accession number that correspond to a previously internal IMGT accession number. See the correspondence table.

IMGT notes: ↑

1. Sequence assigned arbitrarily and temporarily to allele*01 in the absence of cDNA and complete genomic sequence
2. The mouse IGHD gene lacks the CH2 exon but shows a relic sequence just to the right of a (CT)30-(CA)30 repeat in the intron between CH1 and CH3.
3. Sequencing errors of the original K00689 accession number have been corrected in this X01857 accession number
4. Partial C-GENE: partial CH1 in 3'.
5. In the IGHA gene, the hinge (H) and the CH2 are joined in a single exon
6. The CH2 codon 50 amino acid difference with the MOPC511 protein sequence was noted by the authors (PMID:6801659). However, it is not excluded, from the allele alignment, that the ct nucleotide inversion in J00475 may result from a sequencing error.
7. Sequence assigned arbitrarily and temporarily to allele*01 in the absence of cDNA and complete genomic sequence.
8. Partial C-GENE: partial CH2 in 3'.
9. The DELETION of one nucleotide (between positions 5898/5899 in the EMBL flat file) in the CH1 seems to be a typing error.
10. Contig.
11. Partial C-GENE: partial CH1 in 5'.
12. Sequencing errors of the original K00689 accession number have been corrected in this X01857 accession number.
13. Partial C-GENE: partial M1 in 3'.
14. Sequence assigned arbitrarily and temporarily to allele*02 in the absence of cDNA and complete genomic sequence.
15. Partial C-GENE: partial CH4 in 3'.
16. V00793 is a secondary accession number of J00453, however it differs from J00453, the Mus musculus IGHG1*01 reference sequence by one nucleotide difference (CH1 g250.2>c, E84.2>Q) which is an assembly sequencing error.
17. Mus musculus musculus wild-derived mice from Austria.
18. Contig: from 1 to 1921 bp (PMID:115593) and from 113-1931 (PMID:6803173).
19. The NOD mouse is a model of human insulin-dependent diabetes. This mouse strain was bred from mice in Japan and thus does not share any particular close lineage with BALB/c or C57BL/6 mice ( PMID:9162106).
20. Partial C-GENE: partial CH4 in 5'.
21. Contig: from 1 to 2293 bp (PMID:6795090) and from 2290-2472 (PMID:6282840).
22. The mouse IGHD gene lacks the CH2 exon but shows a relic sequence just to the right of a (CT)30-(CA)30 repeat in the intron between CH1 and CH3 (PMID:6417547). The mouse IGHD gene has an additional unusual exon designated as CH-X between the CHS and M1 exons (PMID:6801528). This unusual exon (J00450.1: 745..812) has only been located in genomic DNA (AC073553: 153760..153827, RP23-270B12, strain C57BL/6J ; AJ851868: 1229276..1229343, strain 129/Sv), but not in cDNA. This exon was not identified in Rattus norvegicus (Norway rat) genomic sequence (31/10/06, F. Bellahcene and M.-P. Lefranc).
23. Duplicated IGHG2 genes were found in Japanese mice, Mus musculus molossinus (PMID:6283372) and Mus musculus subspecies of Chinese wild mice ( PMID:6336561) and in Mus musculus musculus strain MAI (PMID:2563358). Sequence analysis comparison shows that the gene previously defined as gamma2a in C57BL/6 (PMID:6297797) corresponds in fact to IGHG2C (PMID:6336561/PMID:2510996)

IMGT references: ↑

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