IMGT Repertoire (IG and TR)

Non canonical V-NONAMER: AAAAAAAAA instead of ACAAAAATA.
no L-PART2, frameshift in V-REGION: deletion of 1 nt in FR1-IMGT
no L-PART1, no ACCEPTOR-SPLICE, frameshift in V-REGION: deletion of 1 nt in FR1-IMGT
no L-PART1, no L-PART2, deletions in V-REGION: AA 1 to 24 are missing, frameshift in V-REGION: insertion of 1 nt in FR2-IMGT
no L-PART2, deletions in V-REGION: AA 1 to 24 are missing
Pseudogene because of mutations in the L-PART1
Because of non canonical V-HEPTAMER: CACAGAC instead of CACAGTG and DELETION in the V-SPACER (only 4 nucleotides instead 12 nucleotides).
Pseudogene because of a lot of mutations, insertions and deletions leading to frameshifts
no DONOR-SPLICE, no L-PART2, frameshifts in V-REGION: deletion of 1 nt and 1 nt and 1 nt in FR1-IMGT, several STOP-CODON in V-REGION, no V-RS
Pseudogene because of INSERTIONs and DELETIONs in the V-REGION leading to frameshifts. No L-PART2.
Pseudogene because of a lot of DELETIONs and INSERTIONs in the V-REGION leading to frameshifts. No L-PART2.
Pseudogene because of INSERTIONs in the CDR1-IMGT and in the FR3-IMGT leading to frameshifts
Pseudogene because of a lot of INSERTIONS and DELETIONS leading to frameshifts
Pseudogene because of an INSERTION in the FR3-IMGT leading to a frameshift
Pseudogene because of mutations in the V-REGION and DELETION of five bp in the FR1_IMGT leading to frameshift.
Pseudogen because of INSERTION of 1 bp in FR3_IMGT leading to a frameshift.
Pseudogen because of STOP-CODONs in FR2-IMGT and INSERTION of 1 bp in FR3-IMGT.
Pseudogen due to a 570-bp insertion between FR3_IMGT and CDR3_IMGT leading to a frameshift in the CDR3_IMGT.
deletion of 9 nucleotides in FR2-IMGT, corresponding to the codons 49, 50 and 51 according to the IMGT unique numbering for V-DOMAIN, stop codon at codon 67 in FR3-IMGT, stop codon at codon 67 in FR3-IMGT, insertion of 1 nt in FR3-IMGT, No DONOR-SPLICE at the end of L-PART-1
no L-PART1, frameshifts in V-REGION: several deletions
frameshift in L-PART1
because of no conserved CONSERVED-TRP.
no CONSERVED-TRP: Arg instead of Trp
Pseudogene because of a DELETION of 3 pb in the L-PART1
INIT-CODON is replaced by Tyr
Non canonical V-NONAMER: ACCCTCTAA instead of ACAAAAACC.
Pseudogene because of mutation in the FR2-IMGT leading to a STOP-CODON and DELETION in the FR3-IMGT leading to a frameshift
STOP-CODON in V-REGION: position 39
noncanonical ACCEPTOR-SPLICE: nacnn instead of nagnn
Pseudogene because of an INSERTION of 1 pb in the L-PART1, and STOP-CODONs in FR2-IMGT
Pseudogene due to a STOP-CODON in the IMGT-FR2
Pseudogene because of no INIT-CODON and STOP-CODON in the FR2-IMGT
Pseudogene due to INSERTIONs and DELETIONs in the V-REGION leading to frameshifts
no L-PART1, deletions in V-REGION: AA 85 to AA 111 are missing, no V-RS
no L-PART1, truncated pseudogene, no V-RS
ORF due to a non canonical V-HEPTAMER: CACAGAG instead of CACAGTG
Pseudogene due to a STOP-CODON in FR2-IMGT, INSERTIONs in FR3-IMGT and DELETION in CDR3-IMGT leading to frameshifts.
Deletion of 7 amino acids in FR1-IMGT
Because of non canonical V-HEPTAMER: CACAGAG instead of CACAGTG.
Even if the V-HEPTAMER sequence is not canonical, the gene is functional because of it has been found in a productive transcript.
Pseudogene due to an INSERTION in the IMGT-FR3 leading to a frameshift.
frameshift in V-REGION
Pseudogene because of a STOP-CODON instead of the 1st-CYS in the FR1-IMGT
Pseudogene because of a STOP-CODON in the FR3-IMGT
CONSERVED_TRP is replaced by Leu
Non canonical V-HEPTAMER: CACAATG instead of CACAGTG.
CONSERVED_TRP is replaced by a Gly
Pseudogene because of a DELETION in the CDR1-IMGT leading a frameshift.
Pseudogene because of a DELETION in the FR1-IMGT and in the FR2-IMGT leading frameshifts.
Pseudogene because of an INSERTION and a DELETION in the FR1-IMGT.
STOP-CODON in V-REGION: position 43, frameshift in V-REGION: deletion of 1 nt in FR3-IMGT
Pseudogene due to a STOP-CODON in the FR2-IMGT
Pseudogene due to a DELETION in the FR3-IMGT leading a frameshift. No INIT-CODON.
noncanonical V-HEPTAMER: caagtg instead of cacagtg
Pseudogene due to an INSERTION in the CDR2-IMGT, a DELETION in the L-PART1 and FR3-IMGT and mutations
frameshift in L-PART1, deletions in V-REGION: AA 90 to 111 are missing, no V-RS
Pseudogene due to an INSERTION in the FR1-IMGT leading to a frameshift
Pseudogene because of an INSERTION in the FR1-IMGT leading to a frameshift
several STOP-CODON in V-REGION, frameshift in V-REGION: deletion of 1 nt in FR3-IMGT
STOP-CODON in L-PART1, no CONSERVED-TRP: STOP-CODON instead of Trp, STOP-CODON in V-REGION: position 44
STOP-CODON in L-PART1, frameshifts in V-REGION: several insertions and deletions, no V-RS
Pseudogene of frameshifts, vestigial gene
Pseudogene because of frameshifts, vestigial gene
in frame STOP-CODONs in V-REGION at positions AA 41, 44, 69 and 92, in frame STOP-CODON in L-PART1
frameshift in FR3-IMGT, no V-RS
Pseudogene due to INSERTIONs in the FR1-IMGT and in the FR2-IMGT leading to frameshifts, and STOP-CODON in L-PART1.
frameshift in V-REGION, in frame STOP-CODON in L-PART1
frameshift in L-PART2, frameshifts in V-REGION: several insertions and deletions, no V-RS
frameshifts in V-REGION: several insertions and deletions, no V-RS
frameshift in L-PART2, no INIT-CODON: STOP-CODON instead of Met, STOP-CODON in L-PART1, frameshifts in V-REGION: several insertions and deletions, truncated pseudogene, no V-RS
Pseudogene because of STOP-CODONs in the FR1-IMGT and FR2-IMGT
STOP-CODON in L-PART1, no CONSERVED-TRP: STOP-CODON instead of Trp, several STOP-CODON in V-REGION
frameshift in L-PART1, frameshifts in V-REGION: several insertions and deletions, no V-RS
Pseudogene because of STOP-CODONs in the L-PART1, the FR1-IMGT and the FR2-IMGT
Probably functional, the accession number refers to a DNA genomic sequence but is not known as being germline or rearranged.
Pseudogene because of STOP-CODONs in the L-PART1 and the FR2-IMGT, and a DELETION in the FR3-IMGT
Pseudogene due to DELETIONs in the V-REGION leading to frameshifts
Pseudogene because of DELETIONs leading to frameshifts in V-REGION
Despite its non-canonical V-HEPTAMER, IGKV14-126*01 is functional in C57BL/6J (and also in BALB/c, NOD) as found rearranged in cDNA with defined specificity.
Pseudogene because of an INSERTION of one nucleotide a at codon 6 (nt 18), leading to a frameshift
Pseudogene because of DELETIONs in the FR1-IMGT and in the FR3-IMGT leading to frameshifts
Pseudogene because of DELETION of the ACCEPTOR-SPLICE, DELETION of 12 bp in the FR1-IMGT, DELETION of 1 bp and INSERTION of 1 bp in the CDR3-IMGT.
Pseudogene because of a DELETION in the FR3-IMGT.
several STOP-CODON in V-REGION
Pseudogene due to STOP-CODONs in the FR1-IMGT and the FR3-IMGT No L-PART1.
Pseudogene because of a lot of DELETIONs and INSERTIONs in the V-REGION leading to frameshifts
Pseudogene because of several INSERTIONs in the L-PART1 and several STOP-CODONs in the FR1-IMGT and in the FR2-IMGT
Non canonical DONOR_SPLICE: NGC instead of NGT.
Pseudogen because of DELETION of 1 bp in the FR1-IMGT and DELETION of 3 bp in the CDR2-IMGT leading to frameshifts.
this sequence come from "Mus musculus" confirmed by alignment with IMGT/V-QUEST on 22 June 2007, correction of taxon assignment asked to GenBank and corrected on 24-Jun-2007
frameshift in V-REGION: deletion of 1 nt in FR2-IMGT
This sequence, which differs from the germline mapped reference sequence by 5 nucleotides, can be considered as temporarily an allele.
This sequence, which differs from the germline mapped reference sequence by 2 nucleotides, can be considered as temporarily an allele.
Southeastern Asian house mouse (Mus musculus castaneus) species.
Sequencing error, deletion of 22 bp between the FR1-IMGT and the CDR1-IMGT at position 780/781
In frame STOP-CODON (positions 332-334) at codon 17 in FR1-IMGT.
Partial V-REGION: only AA66 to 71 are present (partial FR3-IMGT).
This sequence, which differs from the germline mapped reference sequence by 1 nucleotide, can be considered as temporarily an allele.
These sequences, which differ from the nearest mapped germline gene (AJ235968) by respectively 11, 9 and 15 nucleotides, can be considered as new unmapped genes.
This sequence, which differs from the germline mapped reference sequence by 8 nucleotides, can be considered as temporarily an allele.
Japanese wild mouse (Mus musculus molossinus) species.
Partial V-REGION: AA102 to 104 are missing (partial FR3-IMGT).
These sequences, which differ from the germline mapped reference sequence by respectively 3 and 7 nucleotides, can be considered as temporarily alleles.
This sequence, which differs from the nearest mapped germline gene (AJ132683) by 21 nucleotides, can be considered as a new unmapped gene.
The IGKV4-52*01 (AJ239198) and the IGKV4-54*01 (AJ231223) V-REGION nucleotide sequences are 100% identical. These two genes differ by one nucleotide in their L-PART2 (at position 12 according to the IMGT numbering).IGKV 4-52 is not found in BAC clone AC153615.It is not yet known if IGHV4-52 represente an allele of IGKV4-54 or polymorphic gene by insertion/deletion.

IMGT references: ↑

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IMGT Repertoire (IG and TR)

Dynamic gene tables per IMGT group and per species (IMGT/GeneTables)

Gene table legend:

IMGT notes: ↑

IMGT references: ↑

IMGT Repertoire (IG and TR)

Dynamic gene tables per IMGT group and per species (IMGT/GeneTables)

Version 1.4

Version 1.3

Version 1.2

Version 1.1

Version 1.0

Gene table legend:

IMGT notes: ↑

IMGT references: ↑