Ferret (Mustela putorius furo) TRD locus
- The ferret (Mustela putorius furo) TRD locus has not be localized on a chromosome so far.
The orientation of the locus is forward (FWD).
- The ferret (Mustela putorius furo) TRA/TRD locus spans 961 kilobases (kb),
from 10 kb upstream of the most 5' gene in the locus, TRAV3 (P), to 10 kb
downstream of the most 3' gene in the locus, TRAC (F).
The Locus representation
encompasses 1 000 kb including the 3' borne DAD1.
- The TRDV genes span 78
kilobases (kb), the TRDJ genes span 13
kilobases (kb), the TRDD genes span 20
kilobases (kb), the TRDC gene spans 5
kilobases (kb)
Clusters
- The TRDV genes are localized in 2 V-CLUSTER:
- the 5' V-CLUSTER, classically in 5' of the TRDD, TRDJ and
TRDC, includes 4 TRDV genes belonging to 4 subgroups (2 genes
are functional and 2 genes are pseudogene).
- the 3' V-CLUSTER, downstream of the TRDC in inverted
orientation, includes 1 TRDV gene (functional).
- The TRDD, TRDJ and TRDC genes are localized in one
D-J-C-CLUSTER between the 5' V-CLUSTER and the 3' V-CLUSTER:
- The CLUSTER includes 2 TRDD genes belonging to 2
subgroups functional, 5 TRDJ (2 genes are functional and 3 gene are pseudogene) and 1 TRDC functional .
Bornes of the ferret (Mustela putorius furo) TRA/TRD locus
- 5' borne is not defined.
- DAD1 (3' borne) has been identified 13 kb downstream of
TRAC, the most 3' gene in the locus.
More information:
Gene table: ferret (Mustela putorius furo) TRDV
Gene table: ferret (Mustela putorius furo) TRDD
Gene table: ferret (Mustela putorius furo) TRDJ
Gene table: ferret (Mustela putorius furo) TRDC
Potential germline repertoire: ferret (Mustela putorius furo) TRDV, TRDD and TRDJ genes
Locus description: ferret (Mustela putorius furo) TRA
See also:
Genomic orientation (IMGT Index)
Taxonomy: Eutheria
